264 related articles for article (PubMed ID: 7728907)
1. The metabolism and DNA binding of the cooked-food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in precision-cut rat liver slices.
Connors MS; Malfatti MA; Felton JS
Chem Biol Interact; 1995 May; 96(2):185-202. PubMed ID: 7728907
[TBL] [Abstract][Full Text] [Related]
2. The role of sulfation and/or acetylation in the metabolism of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Salmonella typhimurium and isolated rat hepatocytes.
Malfatti MA; Buonarati MH; Turteltaub KW; Shen NH; Felton JS
Chem Res Toxicol; 1994; 7(2):139-47. PubMed ID: 8199301
[TBL] [Abstract][Full Text] [Related]
3. The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Malfatti MA; Connors MS; Mauthe RJ; Felton JS
Cancer Res; 1996 Jun; 56(11):2550-5. PubMed ID: 8653696
[TBL] [Abstract][Full Text] [Related]
4. 4-(2-amino-1-methylimidazo[4,5-b]pyrid-6-yl)phenyl sulfate--a major metabolite of the food mutagen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) in the rat.
Alexander J; Wallin H; Holme JA; Becher G
Carcinogenesis; 1989 Aug; 10(8):1543-7. PubMed ID: 2752529
[TBL] [Abstract][Full Text] [Related]
5. Cytotoxicity, DNA adduct formation and DNA repair induced by 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline and 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cultured human mammary epithelial cells.
Fan L; Schut HA; Snyderwine EG
Carcinogenesis; 1995 Apr; 16(4):775-9. PubMed ID: 7728954
[TBL] [Abstract][Full Text] [Related]
6. Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice.
Buonarati MH; Roper M; Morris CJ; Happe JA; Knize MG; Felton JS
Carcinogenesis; 1992 Apr; 13(4):621-7. PubMed ID: 1576715
[TBL] [Abstract][Full Text] [Related]
7. Pancreatic DNA adducts formed in vitro and in vivo by the food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA alphaC).
Pfau W; Brockstedt U; Shirai T; Ito N; Marquardt H
Mutat Res; 1997 Aug; 378(1-2):13-22. PubMed ID: 9288881
[TBL] [Abstract][Full Text] [Related]
8. Effect of glutathione depletion and inhibition of glucuronidation and sulfation on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism, PhIP-DNA adduct formation and unscheduled DNA synthesis in primary rat hepatocytes.
Kaderlik KR; Mulder GJ; Shaddock JG; Casciano DA; Teitel CH; Kadlubar FF
Carcinogenesis; 1994 Aug; 15(8):1711-6. PubMed ID: 8055653
[TBL] [Abstract][Full Text] [Related]
9. Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.
Kaderlik KR; Minchin RF; Mulder GJ; Ilett KF; Daugaard-Jenson M; Teitel CH; Kadlubar FF
Carcinogenesis; 1994 Aug; 15(8):1703-9. PubMed ID: 8055652
[TBL] [Abstract][Full Text] [Related]
10. The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo.
Malfatti MA; Ubick EA; Felton JS
Carcinogenesis; 2005 Nov; 26(11):2019-28. PubMed ID: 15944213
[TBL] [Abstract][Full Text] [Related]
11. DNA-binding and disposition of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in the rat.
Dragsted LO; Frandsen H; Reistad R; Alexander J; Larsen JC
Carcinogenesis; 1995 Nov; 16(11):2785-93. PubMed ID: 7586200
[TBL] [Abstract][Full Text] [Related]
12. Metabolism of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in isolated liver cells from guinea pig, hamster, mouse, and rat.
Alexander J; Fossum BH; Holme JA
Environ Health Perspect; 1994 Oct; 102 Suppl 6(Suppl 6):109-14. PubMed ID: 7889830
[TBL] [Abstract][Full Text] [Related]
13. Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
Turesky RJ; Guengerich FP; Guillouzo A; Langouët S
Mutat Res; 2002 Sep; 506-507():187-95. PubMed ID: 12351158
[TBL] [Abstract][Full Text] [Related]
14. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats.
Turesky RJ; Richoz J; Constable A; Curtis KD; Dingley KH; Turteltaub KW
Chem Biol Interact; 2003 Jun; 145(3):251-65. PubMed ID: 12732453
[TBL] [Abstract][Full Text] [Related]
15. Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate.
Bellamri M; Xiao S; Murugan P; Weight CJ; Turesky RJ
Toxicol Sci; 2018 Jun; 163(2):543-556. PubMed ID: 29596660
[TBL] [Abstract][Full Text] [Related]
16. A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
Gu D; McNaughton L; Lemaster D; Lake BG; Gooderham NJ; Kadlubar FF; Turesky RJ
Chem Res Toxicol; 2010 Apr; 23(4):788-801. PubMed ID: 20192249
[TBL] [Abstract][Full Text] [Related]
17. Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5-b]pyridine in Human Plasma and Hepatocytes.
Wang Y; Peng L; Bellamri M; Langouët S; Turesky RJ
Chem Res Toxicol; 2015 May; 28(5):1045-59. PubMed ID: 25815793
[TBL] [Abstract][Full Text] [Related]
18. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Frandsen H; Alexander J
Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
[TBL] [Abstract][Full Text] [Related]
19. Metabolism of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by lactating Fischer 344 rats and their nursing pups.
Davis CD; Ghoshal A; Schut HA; Snyderwine EG
J Natl Cancer Inst; 1994 Jul; 86(14):1065-70. PubMed ID: 8021955
[TBL] [Abstract][Full Text] [Related]
20. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans.
Malfatti MA; Dingley KH; Nowell-Kadlubar S; Ubick EA; Mulakken N; Nelson D; Lang NP; Felton JS; Turteltaub KW
Cancer Res; 2006 Nov; 66(21):10541-7. PubMed ID: 17079477
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
