141 related articles for article (PubMed ID: 7731013)
1. New (2-methoxyphenyl)piperazine derivatives as 5-HT1A receptor ligands with reduced alpha 1-adrenergic activity. Synthesis and structure-affinity relationships.
Orjales A; Alonso-Cires L; Labeaga L; Corcóstegui R
J Med Chem; 1995 Apr; 38(8):1273-7. PubMed ID: 7731013
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
López-Rodríguez ML; Morcillo MJ; Rovat TK; Fernández E; Vicente B; Sanz AM; Hernández M; Orensanz L
J Med Chem; 1999 Jan; 42(1):36-49. PubMed ID: 9888831
[TBL] [Abstract][Full Text] [Related]
3. Analogues of the 5-HT1A serotonin antagonist 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine with reduced alpha 1-adrenergic affinity.
Raghupathi RK; Rydelek-Fitzgerald L; Teitler M; Glennon RA
J Med Chem; 1991 Aug; 34(8):2633-8. PubMed ID: 1652026
[TBL] [Abstract][Full Text] [Related]
4. trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Lacivita E; Tortorella V; Leonardi A; Poggesi E; Testa R
J Med Chem; 2001 Dec; 44(25):4431-42. PubMed ID: 11728188
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, alpha-adrenoceptors affinity and alpha 1-adrenoceptor antagonistic properties of some 1,4-substituted piperazine derivatives.
Marona H; Kubacka M; Filipek B; Siwek A; Dybała M; Szneler E; Pociecha T; Gunia A; Waszkielewicz AM
Pharmazie; 2011 Oct; 66(10):733-9. PubMed ID: 22026152
[TBL] [Abstract][Full Text] [Related]
6. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
[TBL] [Abstract][Full Text] [Related]
7. 1-Substituted-4-[3-(1,2,3,4-tetrahydro-5- or 7-methoxynaphthalen-1-yl)propyl]piperazines: influence of the N-1 piperazine substituent on 5-HT1A receptor affinity and selectivity versus D2 and alpha1 receptors. Part 6.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
Bioorg Med Chem; 2000 May; 8(5):873-81. PubMed ID: 10881999
[TBL] [Abstract][Full Text] [Related]
8. [[(Arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands.
Modica M; Santagati M; Russo F; Parotti L; De Gioia L; Selvaggini C; Salmona M; Mennini T
J Med Chem; 1997 Feb; 40(4):574-85. PubMed ID: 9046348
[TBL] [Abstract][Full Text] [Related]
9. 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
J Med Chem; 1999 Feb; 42(3):490-6. PubMed ID: 9986719
[TBL] [Abstract][Full Text] [Related]
10. 9-substituted 1,2,3,4-tetrahydro-beta-carbolin-1-ones, new 5-HT1A and 5-HT2A receptor ligands.
Mokrosz MJ; Boksa J; Charakchieva-Minol S; Wesołowska A; Borycz J
Pol J Pharmacol; 1999; 51(4):351-6. PubMed ID: 10540967
[TBL] [Abstract][Full Text] [Related]
11. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
12. New pyridobenzodiazepine derivatives: modifications of the basic side chain differentially modulate binding to dopamine (D(4.2), D(2L)) and serotonin (5-HT(2A)) receptors.
Liégeois JF; Eyrolles L; Ellenbroek BA; Lejeune C; Carato P; Bruhwyler J; Géczy J; Damas J; Delarge J
J Med Chem; 2002 Nov; 45(23):5136-49. PubMed ID: 12408724
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.
López-Rodríguez ML; Rosado ML; Benhamú B; Morcillo MJ; Sanz AM; Orensanz L; Beneitez ME; Fuentes JA; Manzanares J
J Med Chem; 1996 Oct; 39(22):4439-50. PubMed ID: 8893838
[TBL] [Abstract][Full Text] [Related]
14. Isoindol-1-one analogues of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridyl)-p-iodobenzamido]ethyl]pipera zine (p-MPPI) as 5-HT1A receptor ligands.
Zhuang ZP; Kung MP; Mu M; Kung HF
J Med Chem; 1998 Jan; 41(2):157-66. PubMed ID: 9457239
[TBL] [Abstract][Full Text] [Related]
15. High potent and selective arylpiperazine derivatives as ligands for the 5-HT1A receptor.
Modica M; Santagati M; Santagati A; Russo F; Cagnotto A; Goegan M; Mennini T
Bioorg Med Chem Lett; 2000 May; 10(10):1089-92. PubMed ID: 10843224
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands.
Caliendo G; Fiorino F; Grieco P; Perissutti E; Santagada V; Severino B; Bruni G; Romeo MR
Bioorg Med Chem; 2000 Mar; 8(3):533-8. PubMed ID: 10732969
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and structure-activity relationships of a new model of arylpiperazines. Study of the 5-HT(1a)/alpha(1)-adrenergic receptor affinity by classical hansch analysis, artificial neural networks, and computational simulation of ligand recognition.
López-Rodríguez ML; Morcillo MJ; Fernández E; Rosado ML; Pardo L; Schaper K
J Med Chem; 2001 Jan; 44(2):198-207. PubMed ID: 11170629
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationships of a new model of arylpiperazines. 3.1 2-[omega-(4-arylpiperazin-1-yl)alkyl]perhydropyrrolo- [1,2-c]imidazoles and -perhydroimidazo[1,5-a]pyridines: study of the influence of the terminal amide fragment on 5-HT1A affinity/selectivity.
López-Rodríguez ML; Morcillo MJ; Fernández E; Porras E; Murcia M; Sanz AM; Orensanz L
J Med Chem; 1997 Aug; 40(16):2653-6. PubMed ID: 9258372
[TBL] [Abstract][Full Text] [Related]
19. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
Fiorino F; Perissutti E; Severino B; Santagada V; Cirillo D; Terracciano S; Massarelli P; Bruni G; Collavoli E; Renner C; Caliendo G
J Med Chem; 2005 Aug; 48(17):5495-503. PubMed ID: 16107148
[TBL] [Abstract][Full Text] [Related]
20. Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands.
Glennon RA; Naiman NA; Lyon RA; Titeler M
J Med Chem; 1988 Oct; 31(10):1968-71. PubMed ID: 3172131
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
