95 related articles for article (PubMed ID: 7733991)
21. Effect on substrate binding of an alteration at the conserved aspartic acid-162 in herpes simplex virus type 1 thymidine kinase.
Black ME; Rechtin TM; Drake RR
J Gen Virol; 1996 Jul; 77 ( Pt 7)():1521-7. PubMed ID: 8757995
[TBL] [Abstract][Full Text] [Related]
22. Characterization of multiple nuclear localization signals in herpes simplex virus type 1 thymidine kinase.
Degrève B; Esnouf R; De Clercq E; Balzarini J
Biochem Biophys Res Commun; 1999 Oct; 264(2):338-42. PubMed ID: 10529365
[TBL] [Abstract][Full Text] [Related]
23. Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing.
Black ME; Kokoris MS; Sabo P
Cancer Res; 2001 Apr; 61(7):3022-6. PubMed ID: 11306482
[TBL] [Abstract][Full Text] [Related]
24. Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.
Manikowski A; Verri A; Lossani A; Gebhardt BM; Gambino J; Focher F; Spadari S; Wright GE
J Med Chem; 2005 Jun; 48(11):3919-29. PubMed ID: 15916444
[TBL] [Abstract][Full Text] [Related]
25. Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
Degrève B; Esnouf R; De Clercq E; Balzarini J
Mol Pharmacol; 2001 Feb; 59(2):285-93. PubMed ID: 11160865
[TBL] [Abstract][Full Text] [Related]
26. A designed equine herpes thymidine kinase (EHV4 TK) variant improves ganciclovir-induced cell-killing.
McSorley T; Ort S; Monnerjahn C; Konrad M
Biochem Pharmacol; 2014 Feb; 87(3):435-44. PubMed ID: 24316433
[TBL] [Abstract][Full Text] [Related]
27. Analysis of the relationship between cellular thymidine kinase activity and virulence of thymidine kinase-negative herpes simplex virus types 1 and 2.
Suzutani T; Koyano S; Takada M; Yoshida I; Azuma M
Microbiol Immunol; 1995; 39(10):787-94. PubMed ID: 8577269
[TBL] [Abstract][Full Text] [Related]
28. Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
Gardberg A; Shuvalova L; Monnerjahn C; Konrad M; Lavie A
Structure; 2003 Oct; 11(10):1265-77. PubMed ID: 14527394
[TBL] [Abstract][Full Text] [Related]
29. Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells.
Shewach DS; Zerbe LK; Hughes TL; Roessler BJ; Breakefield XO; Davidson BL
Cancer Gene Ther; 1994 Jun; 1(2):107-12. PubMed ID: 7621241
[TBL] [Abstract][Full Text] [Related]
30. Resistance of herpes simplex virus type 1 to acyclovir: thymidine kinase gene mutagenesis study.
Frobert E; Ooka T; Cortay JC; Lina B; Thouvenot D; Morfin F
Antiviral Res; 2007 Feb; 73(2):147-50. PubMed ID: 16970995
[TBL] [Abstract][Full Text] [Related]
31. Structure-specificity features of HSV-1 thymidine kinases.
Evans JS; Lock KP; Levine BA; Champness JN; Sanderson MR; Summers WC; Buchan A
Biochem Soc Trans; 1997 Nov; 25(4):S621. PubMed ID: 9450049
[No Abstract] [Full Text] [Related]
32. Effects of mutations on herpes simplex virus 1 thymidine kinase functionality: an in vitro assay based on detection of monophosphate forms of acyclovir and thymidine using HPLC/DAD.
Malartre N; Boulieu R; Falah N; Cortay JC; Lina B; Morfin F; Frobert E
Antiviral Res; 2012 Sep; 95(3):224-8. PubMed ID: 22796575
[TBL] [Abstract][Full Text] [Related]
33. Stepwise characterization of non-synonymous mutations in the HSV-1 thymidine kinase gene by different functional assays.
Kaspar M; Bohn-Wippert K; Bellstedt P; Häfner S; Görlach M; Sauerbrei A
J Virol Methods; 2017 Sep; 247():51-57. PubMed ID: 28576448
[TBL] [Abstract][Full Text] [Related]
34. Significance of amino acid substitutions in the thymidine kinase gene of herpes simplex virus type 1 for resistance.
Sauerbrei A; Liermann K; Bohn K; Henke A; Zell R; Gronowitz S; Wutzler P
Antiviral Res; 2012 Nov; 96(2):105-7. PubMed ID: 22906425
[TBL] [Abstract][Full Text] [Related]
35. A net +1 frameshift permits synthesis of thymidine kinase from a drug-resistant herpes simplex virus mutant.
Hwang CB; Horsburgh B; Pelosi E; Roberts S; Digard P; Coen DM
Proc Natl Acad Sci U S A; 1994 Jun; 91(12):5461-5. PubMed ID: 8202508
[TBL] [Abstract][Full Text] [Related]
36. Proteolytic mapping of the thymidine/thymidylate binding site of herpes simplex virus type 1 thymidine kinase: a general photoaffinity labeling method for identifying active-site peptides.
Rechtin TM; Black ME; Drake RR
Anal Biochem; 1996 May; 237(1):135-40. PubMed ID: 8660548
[TBL] [Abstract][Full Text] [Related]
37. Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir.
Gustafson EA; Schinazi RF; Fingeroth JD
J Virol; 2000 Jan; 74(2):684-92. PubMed ID: 10623730
[TBL] [Abstract][Full Text] [Related]
38. Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes.
Schubert A; Gentner E; Bohn K; Schwarz M; Mertens T; Sauerbrei A
Antiviral Res; 2014 Jul; 107():16-22. PubMed ID: 24747042
[TBL] [Abstract][Full Text] [Related]
39. Artificial mutants generated by the insertion of random oligonucleotides into the putative nucleoside binding site of the HSV-1 thymidine kinase gene.
Dube DK; Parker JD; French DC; Cahill DS; Dube S; Horwitz MS; Munir KM; Loeb LA
Biochemistry; 1991 Dec; 30(51):11760-7. PubMed ID: 1661147
[TBL] [Abstract][Full Text] [Related]
40. Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Champness JN; Bennett MS; Wien F; Visse R; Summers WC; Herdewijn P; de Clerq E; Ostrowski T; Jarvest RL; Sanderson MR
Proteins; 1998 Aug; 32(3):350-61. PubMed ID: 9715911
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
