BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 7741767)

  • 21. D282, a non-nucleoside inhibitor of influenza virus infection that interferes with de novo pyrimidine biosynthesis.
    Smee DF; Hurst BL; Day CW
    Antivir Chem Chemother; 2012 Aug; 22(6):263-72. PubMed ID: 22516927
    [TBL] [Abstract][Full Text] [Related]  

  • 22. In vitro and in Vivo inhibition of immunoglobulin secretion by the immunosuppressive compound HR325 is reversed by exogenous uridine.
    Thomson TA; Spinella-Jaegle S; Francesconi E; Meakin C; Millet S; Flao KL; Hidden H; Ruuth E
    Scand J Immunol; 2002 Jul; 56(1):35-42. PubMed ID: 12100469
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Effects of atovaquone and other inhibitors on Pneumocystis carinii dihydroorotate dehydrogenase.
    Ittarat I; Asawamahasakda W; Bartlett MS; Smith JW; Meshnick SR
    Antimicrob Agents Chemother; 1995 Feb; 39(2):325-8. PubMed ID: 7726490
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans.
    Zameitat E; Gojković Z; Knecht W; Piskur J; Löffler M
    FEBS J; 2006 Jul; 273(14):3183-91. PubMed ID: 16774642
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Drosophila melanogaster dihydroorotate dehydrogenase: the N-terminus is important for biological function in vivo but not for catalytic properties in vitro.
    Löffler M; Knecht W; Rawls J; Ullrich A; Dietz C
    Insect Biochem Mol Biol; 2002 Sep; 32(9):1159-69. PubMed ID: 12213251
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The relation between inhibition of cell growth and of dihydroorotic acid dehydrogenase by brequinar sodium.
    de Kant E; Pinedo HM; Laurensse E; Peters GJ
    Cancer Lett; 1989 Jul; 46(2):123-7. PubMed ID: 2546667
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis.
    Cherwinski HM; Cohn RG; Cheung P; Webster DJ; Xu YZ; Caulfield JP; Young JM; Nakano G; Ransom JT
    J Pharmacol Exp Ther; 1995 Nov; 275(2):1043-9. PubMed ID: 7473131
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Re-evaluation of Brequinar sodium, a dihydroorotate dehydrogenase inhibitor.
    Peters GJ
    Nucleosides Nucleotides Nucleic Acids; 2018; 37(12):666-678. PubMed ID: 30663496
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Histidine to alanine mutants of human dihydroorotate dehydrogenase. Identification of a brequinar-resistant mutant enzyme.
    Davis JP; Copeland RA
    Biochem Pharmacol; 1997 Aug; 54(4):459-65. PubMed ID: 9313772
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Recombinant expression of N-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase. A versatile tool to rate inhibitor effects?
    Ullrich A; Knecht W; Fries M; Löffler M
    Eur J Biochem; 2001 Mar; 268(6):1861-8. PubMed ID: 11248707
    [TBL] [Abstract][Full Text] [Related]  

  • 31. dCTP levels are maintained in Plasmodium falciparum subjected to pyrimidine deficiency or excess.
    Seymour KK; Yeo AE; Rieckmann KH; Christopherson RI
    Ann Trop Med Parasitol; 1997 Sep; 91(6):603-9. PubMed ID: 9425362
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cellular pharmacology of DUP-785, a new anticancer agent.
    Anderson LW; Strong JM; Cysyk RL
    Cancer Commun; 1989; 1(6):381-7. PubMed ID: 2562006
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Retention of in vivo antipyrimidine effects of Brequinar sodium (DUP-785; NSC 368390) in murine liver, bone marrow and colon cancer.
    Peters GJ; Nadal JC; Laurensse EJ; de Kant E; Pinedo HM
    Biochem Pharmacol; 1990 Jan; 39(1):135-44. PubMed ID: 2153375
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structure-activity relationship of a pyrimidine receptor in the rat isolated superior cervical ganglion.
    Connolly GP; Harrison PJ
    Br J Pharmacol; 1995 Nov; 116(6):2764-70. PubMed ID: 8591002
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Dihydroorotate dehydrogenase is a high affinity binding protein for A77 1726 and mediator of a range of biological effects of the immunomodulatory compound.
    Williamson RA; Yea CM; Robson PA; Curnock AP; Gadher S; Hambleton AB; Woodward K; Bruneau JM; Hambleton P; Moss D; Thomson TA; Spinella-Jaegle S; Morand P; Courtin O; Sautés C; Westwood R; Hercend T; Kuo EA; Ruuth E
    J Biol Chem; 1995 Sep; 270(38):22467-72. PubMed ID: 7673235
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dihydroorotate dehydrogenase. Profile of a novel target for antiproliferative and immunosuppressive drugs.
    Löffler M; Grein K; Knecht W; Klein A; Bergjohann U
    Adv Exp Med Biol; 1998; 431():507-13. PubMed ID: 9598119
    [No Abstract]   [Full Text] [Related]  

  • 37. Biosynthesis and scavenging of pyrimidines by pathogenic mycobacteria.
    Wheeler PR
    J Gen Microbiol; 1990 Jan; 136(1):189-201. PubMed ID: 2191077
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Evidence for transformation-related increase in CTP synthetase activity in situ in human lymphoblastic leukemia.
    van den Berg AA; van Lenthe H; Busch S; de Korte D; Roos D; van Kuilenburg AB; van Gennip AH
    Eur J Biochem; 1993 Aug; 216(1):161-7. PubMed ID: 8365402
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Anti-arthritic effects of KF20444, a new immunosuppressive compound inhibiting dihydroorotate dehydrogenase, on rat collagen-induced arthritis.
    Kobayashi K; Nakashima A; Nagata H; Nakajima H; Yamaguchi K; Sato S; Miki I
    Inflamm Res; 2001 Jan; 50(1):24-31. PubMed ID: 11235018
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitro.
    Hammond DJ; Burchell JR; Pudney M
    Mol Biochem Parasitol; 1985 Jan; 14(1):97-109. PubMed ID: 3885032
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.