315 related articles for article (PubMed ID: 7746280)
21. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
Siegel D; Gibson NW; Preusch PC; Ross D
Cancer Res; 1990 Nov; 50(22):7293-300. PubMed ID: 2121335
[TBL] [Abstract][Full Text] [Related]
22. Interaction of flavones and their bromoacetyl derivatives with NAD(P)H:quinone acceptor oxidoreductase.
Chen S; Deng PS; Swiderek K; Li M; Chan SI
Mol Pharmacol; 1995 Feb; 47(2):419-24. PubMed ID: 7870053
[TBL] [Abstract][Full Text] [Related]
23. Indolequinone antitumour agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase.
Newsome JJ; Swann E; Hassani M; Bray KC; Slawin AM; Beall HD; Moody CJ
Org Biomol Chem; 2007 May; 5(10):1629-40. PubMed ID: 17571194
[TBL] [Abstract][Full Text] [Related]
24. DT-diaphorase protects cells from the hypoxic cytotoxicity of indoloquinone EO9.
Plumb JA; Gerritsen M; Workman P
Br J Cancer; 1994 Dec; 70(6):1136-43. PubMed ID: 7526885
[TBL] [Abstract][Full Text] [Related]
25. Role of Nad(P)h: quinone oxidoreductase in the regulation of intracellular redox state.
Mohora M
Rom J Intern Med; 2000-2001; 38-39():33-50. PubMed ID: 15529570
[TBL] [Abstract][Full Text] [Related]
26. Construction of a human cytochrome P450 1A1: rat NADPH-cytochrome P450 reductase fusion protein cDNA and expression in Escherichia coli, purification, and catalytic properties of the enzyme in bacterial cells and after purification.
Chun YJ; Shimada T; Guengerich FP
Arch Biochem Biophys; 1996 Jun; 330(1):48-58. PubMed ID: 8651703
[TBL] [Abstract][Full Text] [Related]
27. Inhibition of rat liver NAD(P)H:quinone acceptor oxidoreductase (DT-diaphorase) by flavonoids isolated from the Chinese herb scutellariae radix (Huang Qin).
Liu XF; Liu ML; Iyanagi T; Legesse K; Lee TD; Chen SA
Mol Pharmacol; 1990 Jun; 37(6):911-5. PubMed ID: 1694261
[TBL] [Abstract][Full Text] [Related]
28. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Qiu XB; Cadenas E
Arch Biochem Biophys; 1997 Oct; 346(2):241-51. PubMed ID: 9343371
[TBL] [Abstract][Full Text] [Related]
29. Involvement of DT-diaphorase (EC 1.6.99.2) in the DNA cross-linking and sequence selectivity of the bioreductive anti-tumour agent EO9.
Bailey SM; Wyatt MD; Friedlos F; Hartley JA; Knox RJ; Lewis AD; Workman P
Br J Cancer; 1997; 76(12):1596-603. PubMed ID: 9413948
[TBL] [Abstract][Full Text] [Related]
30. Caffeine, aminoimidazolecarboxamide and dicoumarol, inhibitors of NAD(P)H dehydrogenase (quinone) (DT diaphorase), prevent both the cytotoxicity and DNA interstrand crosslinking produced by 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) in Walker cells.
Roberts JJ; Marchbank T; Kotsaki-Kovatsi VP; Boland MP; Friedlos F; Knox RJ
Biochem Pharmacol; 1989 Nov; 38(22):4137-43. PubMed ID: 2480794
[TBL] [Abstract][Full Text] [Related]
31. [DT-diaphorase].
Mikami K; Shirakusa T; Tsuruo T
Gan To Kagaku Ryoho; 1997 Sep; 24(11):1606-10. PubMed ID: 9309161
[TBL] [Abstract][Full Text] [Related]
32. The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins.
Walton MI; Sugget N; Workman P
Int J Radiat Oncol Biol Phys; 1992; 22(4):643-7. PubMed ID: 1544831
[TBL] [Abstract][Full Text] [Related]
33. Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones.
Gustafson DL; Beall HD; Bolton EM; Ross D; Waldren CA
Mol Pharmacol; 1996 Oct; 50(4):728-35. PubMed ID: 8863816
[TBL] [Abstract][Full Text] [Related]
34. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
Begleiter A; Leith MK; Curphey TJ; Doherty GP
Oncol Res; 1997; 9(6-7):371-82. PubMed ID: 9406243
[TBL] [Abstract][Full Text] [Related]
35. Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling.
Chen S; Wu K; Zhang D; Sherman M; Knox R; Yang CS
Mol Pharmacol; 1999 Aug; 56(2):272-8. PubMed ID: 10419545
[TBL] [Abstract][Full Text] [Related]
36. Kinetics of NAD(P)H:quinone oxidoreductase I (NQO1) inhibition by mitomycin C in vitro and in vivo.
Gustafson DL; Siegel D; Rastatter JC; Merz AL; Parpal JC; Kepa JK; Ross D; Long ME
J Pharmacol Exp Ther; 2003 Jun; 305(3):1079-86. PubMed ID: 12649308
[TBL] [Abstract][Full Text] [Related]
37. A two-domain structure for the two subunits of NAD(P)H:quinone acceptor oxidoreductase.
Chen S; Deng PS; Bailey JM; Swiderek KM
Protein Sci; 1994 Jan; 3(1):51-7. PubMed ID: 7511454
[TBL] [Abstract][Full Text] [Related]
38. Reaction of rat liver DT-diaphorase (NAD(P)H:quinone acceptor reductase) with 5'-[p-(fluorosulfonyl)benzoyl]-adenosine.
Liu XF; Yuan H; Haniu M; Iyanagi T; Shively JE; Chen SA
Mol Pharmacol; 1989 Jun; 35(6):818-22. PubMed ID: 2499768
[TBL] [Abstract][Full Text] [Related]
39. Aziridinyldinitrobenzamides: synthesis and structure-activity relationships for activation by E. coli nitroreductase.
Helsby NA; Atwell GJ; Yang S; Palmer BD; Anderson RF; Pullen SM; Ferry DM; Hogg A; Wilson WR; Denny WA
J Med Chem; 2004 Jun; 47(12):3295-307. PubMed ID: 15163209
[TBL] [Abstract][Full Text] [Related]
40. Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase.
Workman P
Oncol Res; 1994; 6(10-11):461-75. PubMed ID: 7620214
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]