141 related articles for article (PubMed ID: 7746281)
1. GTP depletion induced by IMP dehydrogenase inhibitors blocks RNA-primed DNA synthesis.
Catapano CV; Dayton JS; Mitchell BS; Fernandes DJ
Mol Pharmacol; 1995 May; 47(5):948-55. PubMed ID: 7746281
[TBL] [Abstract][Full Text] [Related]
2. Biochemical differences among four inosinate dehydrogenase inhibitors, mycophenolic acid, ribavirin, tiazofurin, and selenazofurin, studied in mouse lymphoma cell culture.
Lee HJ; Pawlak K; Nguyen BT; Robins RK; Sadée W
Cancer Res; 1985 Nov; 45(11 Pt 1):5512-20. PubMed ID: 2865005
[TBL] [Abstract][Full Text] [Related]
3. Consequences of inhibition of guanine nucleotide synthesis by mycophenolic acid and virazole.
Lowe JK; Brox L; Henderson JF
Cancer Res; 1977 Mar; 37(3):736-43. PubMed ID: 837373
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of primer RNA formation in CCRF-CEM leukemia cells by fludarabine triphosphate.
Catapano CV; Chandler KB; Fernandes DJ
Cancer Res; 1991 Apr; 51(7):1829-35. PubMed ID: 1706219
[TBL] [Abstract][Full Text] [Related]
5. Effects of the inhibitors of IMP dehydrogenase, tiazofurin and mycophenolic acid, on glycoprotein metabolism.
Sokoloski JA; Sartorelli AC
Mol Pharmacol; 1985 Dec; 28(6):567-73. PubMed ID: 2867464
[TBL] [Abstract][Full Text] [Related]
6. Biological effects of inhibition of guanine nucleotide synthesis by mycophenolic acid in cultured neuroblastoma cells.
Cass CE; Lowe JK; Manchak JM; Henderson JF
Cancer Res; 1977 Sep; 37(9):3314-20. PubMed ID: 195725
[TBL] [Abstract][Full Text] [Related]
7. Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase.
Sokoloski JA; Blair OC; Sartorelli AC
Cancer Res; 1986 May; 46(5):2314-9. PubMed ID: 2870796
[TBL] [Abstract][Full Text] [Related]
8. Differentiation and reduction of intracellular GTP levels in HL-60 and U937 cells upon treatment with IMP dehydrogenase inhibitors.
Inai K; Tsutani H; Yamauchi T; Nakamura T; Ueda T
Adv Exp Med Biol; 1998; 431():549-53. PubMed ID: 9598126
[No Abstract] [Full Text] [Related]
9. IMP dehydrogenase inhibitors as immunomodulators.
Mitchell BS; Dayton JS; Turka LA; Thompson CB
Ann N Y Acad Sci; 1993 Jun; 685():217-24. PubMed ID: 8103312
[TBL] [Abstract][Full Text] [Related]
10. Selective inhibitors of GTP synthesis impede exocytotic insulin release from intact rat islets.
Metz SA; Rabaglia ME; Pintar TJ
J Biol Chem; 1992 Jun; 267(18):12517-27. PubMed ID: 1352288
[TBL] [Abstract][Full Text] [Related]
11. Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis.
Li G; Segu VB; Rabaglia ME; Luo RH; Kowluru A; Metz SA
Endocrinology; 1998 Sep; 139(9):3752-62. PubMed ID: 9724027
[TBL] [Abstract][Full Text] [Related]
12. Comparison of the effects of mizoribine with those of azathioprine, 6-mercaptopurine, and mycophenolic acid on T lymphocyte proliferation and purine ribonucleotide metabolism.
Dayton JS; Turka LA; Thompson CB; Mitchell BS
Mol Pharmacol; 1992 Apr; 41(4):671-6. PubMed ID: 1569921
[TBL] [Abstract][Full Text] [Related]
13. Cellular IMPDH enzyme activity is a potential target for the inhibition of Chikungunya virus replication and virus induced apoptosis in cultured mammalian cells.
Khan M; Dhanwani R; Patro IK; Rao PV; Parida MM
Antiviral Res; 2011 Jan; 89(1):1-8. PubMed ID: 21070810
[TBL] [Abstract][Full Text] [Related]
14. Assay method for monitoring the inhibitory effects of antimetabolites on the activity of inosinate dehydrogenase in intact human CEM lymphocytes.
Balzarini J; De Clercq E
Biochem J; 1992 Nov; 287 ( Pt 3)(Pt 3):785-90. PubMed ID: 1359876
[TBL] [Abstract][Full Text] [Related]
15. Selective guanosine phosphate deficiency in hepatoma cells induced by inhibitors of IMP dehydrogenase.
Kaiser WA; Herrmann B; Keppler DO
Hoppe Seylers Z Physiol Chem; 1980 Oct; 361(10):1503-10. PubMed ID: 6108911
[TBL] [Abstract][Full Text] [Related]
16. Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.
Balzarini J; Karlsson A; Wang L; Bohman C; Horská K; Votruba I; Fridland A; Van Aerschot A; Herdewijn P; De Clercq E
J Biol Chem; 1993 Nov; 268(33):24591-8. PubMed ID: 7901217
[TBL] [Abstract][Full Text] [Related]
17. The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase.
Leyssen P; Balzarini J; De Clercq E; Neyts J
J Virol; 2005 Feb; 79(3):1943-7. PubMed ID: 15650220
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia cells in culture by sesquiterpene lactones.
Hall IH; Williams WL; Grippo AA; Lee KH; Holbrook DJ; Chaney SG
Anticancer Res; 1988; 8(1):33-42. PubMed ID: 2895992
[TBL] [Abstract][Full Text] [Related]
19. IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels. Indications of the regulation of GTP cyclohydrolase I activity by restriction of GTP availability in the cells.
Hatakeyama K; Harada T; Kagamiyama H
J Biol Chem; 1992 Oct; 267(29):20734-9. PubMed ID: 1356983
[TBL] [Abstract][Full Text] [Related]
20. Guanine ribonucleotide depletion in mammalian cells. A target of purine antimetabolites.
Nguyen BT; Cohen MB; Sadée W
Cancer Chemother Pharmacol; 1983; 11(2):117-9. PubMed ID: 6578881
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]