These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 7749913)

  • 1. Comparison of the solution structures of microcystin-LR and motuporin.
    Bagu JR; Sönnichsen FD; Williams D; Andersen RJ; Sykes BD; Holmes CF
    Nat Struct Biol; 1995 Feb; 2(2):114-6. PubMed ID: 7749913
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A.
    Bagu JR; Sykes BD; Craig MM; Holmes CF
    J Biol Chem; 1997 Feb; 272(8):5087-97. PubMed ID: 9030574
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins.
    Maynes JT; Luu HA; Cherney MM; Andersen RJ; Williams D; Holmes CF; James MN
    J Mol Biol; 2006 Feb; 356(1):111-20. PubMed ID: 16343532
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular mechanisms underlying he interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases.
    Craig M; Luu HA; McCready TL; Williams D; Andersen RJ; Holmes CF
    Biochem Cell Biol; 1996; 74(4):569-78. PubMed ID: 8960363
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins.
    Dawson JF; Holmes CF
    Front Biosci; 1999 Oct; 4():D646-58. PubMed ID: 10502549
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microcystin analogues comprised only of Adda and a single additional amino acid retain moderate activity as PP1/PP2A inhibitors.
    Gulledge BM; Aggen JB; Eng H; Sweimeh K; Chamberlin AR
    Bioorg Med Chem Lett; 2003 Sep; 13(17):2907-11. PubMed ID: 14611855
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins.
    Holmes CF; Maynes JT; Perreault KR; Dawson JF; James MN
    Curr Med Chem; 2002 Nov; 9(22):1981-9. PubMed ID: 12369866
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The solution NMR structure of a blue-green algae hepatotoxin, microcystin-RR--a comparison with the structure of microcystin-LR.
    Trogen GB; Edlund U; Larsson G; Sethson I
    Eur J Biochem; 1998 Dec; 258(2):301-12. PubMed ID: 9874194
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights derived from the structures of the Ser/Thr phosphatases calcineurin and protein phosphatase 1.
    Lohse DL; Denu JM; Dixon JE
    Structure; 1995 Oct; 3(10):987-90. PubMed ID: 8590008
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases.
    Honkanen RE; Zwiller J; Moore RE; Daily SL; Khatra BS; Dukelow M; Boynton AL
    J Biol Chem; 1990 Nov; 265(32):19401-4. PubMed ID: 2174036
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants.
    MacKintosh C; Beattie KA; Klumpp S; Cohen P; Codd GA
    FEBS Lett; 1990 May; 264(2):187-92. PubMed ID: 2162782
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity.
    Aggen JB; Humphrey JM; Gauss CM; Huang HB; Nairn AC; Chamberlin AR
    Bioorg Med Chem; 1999 Mar; 7(3):543-64. PubMed ID: 10220039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and characterization of hydrophobic microcystins in Canadian freshwater cyanobacteria.
    Craig M; McCready TL; Luu HA; Smillie MA; Dubord P; Holmes CF
    Toxicon; 1993 Dec; 31(12):1541-9. PubMed ID: 8146867
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conformational studies of microcystin-LR using NMR spectroscopy and molecular dynamics calculations.
    Trogen GB; Annila A; Eriksson J; Kontteli M; Meriluoto J; Sethson I; Zdunek J; Edlund U
    Biochemistry; 1996 Mar; 35(10):3197-205. PubMed ID: 8605154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin.
    Hastie CJ; Borthwick EB; Morrison LF; Codd GA; Cohen PT
    Biochim Biophys Acta; 2005 Nov; 1726(2):187-93. PubMed ID: 16046071
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A.
    Gulledge BM; Aggen JB; Chamberlin AR
    Bioorg Med Chem Lett; 2003 Sep; 13(17):2903-6. PubMed ID: 14611854
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding.
    Maynes JT; Perreault KR; Cherney MM; Luu HA; James MN; Holmes CF
    J Biol Chem; 2004 Oct; 279(41):43198-206. PubMed ID: 15280359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins.
    An J; Carmichael WW
    Toxicon; 1994 Dec; 32(12):1495-507. PubMed ID: 7725318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases.
    Eriksson JE; Toivola D; Meriluoto JA; Karaki H; Han YG; Hartshorne D
    Biochem Biophys Res Commun; 1990 Dec; 173(3):1347-53. PubMed ID: 2176489
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based thermodynamic analysis of the dissociation of protein phosphatase-1 catalytic subunit and microcystin-LR docked complexes.
    Lavigne P; Bagu JR; Boyko R; Willard L; Holmes CF; Sykes BD
    Protein Sci; 2000 Feb; 9(2):252-64. PubMed ID: 10716177
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.