BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 7753822)

  • 21. Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct.
    Keskiaho K; Kukkola L; Page AP; Winter AD; Vuoristo J; Sormunen R; Nissi R; Riihimaa P; Myllyharju J
    J Biol Chem; 2008 Apr; 283(16):10679-89. PubMed ID: 18276589
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Cloning of the alpha subunit of prolyl 4-hydroxylase from Drosophila and expression and characterization of the corresponding enzyme tetramer with some unique properties.
    Annunen P; Koivunen P; Kivirikko KI
    J Biol Chem; 1999 Mar; 274(10):6790-6. PubMed ID: 10037780
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Prolyl 4-hydroxylase: molecular cloning and the primary structure of the alpha subunit from chicken embryo.
    Bassuk JA; Kao WW; Herzer P; Kedersha NL; Seyer J; DeMartino JA; Daugherty BL; Mark GE; Berg RA
    Proc Natl Acad Sci U S A; 1989 Oct; 86(19):7382-6. PubMed ID: 2552442
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Characterization of the human and mouse genes for the alpha subunit of type II prolyl 4-hydroxylase. Identification of a previously unknown alternatively spliced exon and its expression in various tissues.
    Nokelainen M; Nissi R; Kukkola L; Helaakoski T; Myllyharju J
    Eur J Biochem; 2001 Oct; 268(20):5300-9. PubMed ID: 11606192
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Three binding sites in protein-disulfide isomerase cooperate in collagen prolyl 4-hydroxylase tetramer assembly.
    Koivunen P; Salo KE; Myllyharju J; Ruddock LW
    J Biol Chem; 2005 Feb; 280(7):5227-35. PubMed ID: 15590633
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Molecular cloning of a multifunctional chicken protein acting as the prolyl 4-hydroxylase beta-subunit, protein disulphide-isomerase and a cellular thyroid-hormone-binding protein. Comparison of cDNA-deduced amino acid sequences with those in other species.
    Parkkonen T; Kivirikko KI; Pihlajaniemi T
    Biochem J; 1988 Dec; 256(3):1005-11. PubMed ID: 2851999
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Characterization of a second Arabidopsis thaliana prolyl 4-hydroxylase with distinct substrate specificity.
    Tiainen P; Myllyharju J; Koivunen P
    J Biol Chem; 2005 Jan; 280(2):1142-8. PubMed ID: 15528200
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Regional assignment of the human gene coding for a multifunctional polypeptide (P4HB) acting as the beta-subunit of prolyl 4-hydroxylase and the enzyme protein disulfide isomerase to 17q25.
    Pajunen L; Jones TA; Goddard A; Sheer D; Solomon E; Pihlajaniemi T; Kivirikko KI
    Cytogenet Cell Genet; 1991; 56(3-4):165-8. PubMed ID: 1647289
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans.
    Winter AD; Page AP
    Mol Cell Biol; 2000 Jun; 20(11):4084-93. PubMed ID: 10805750
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The peptide-substrate-binding domain of human collagen prolyl 4-hydroxylases. Backbone assignments, secondary structure, and binding of proline-rich peptides.
    Hieta R; Kukkola L; Permi P; Pirilä P; Kivirikko KI; Kilpeläinen I; Myllyharju J
    J Biol Chem; 2003 Sep; 278(37):34966-74. PubMed ID: 12824157
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Assembly of human prolyl 4-hydroxylase and type III collagen in the yeast pichia pastoris: formation of a stable enzyme tetramer requires coexpression with collagen and assembly of a stable collagen requires coexpression with prolyl 4-hydroxylase.
    Vuorela A; Myllyharju J; Nissi R; Pihlajaniemi T; Kivirikko KI
    EMBO J; 1997 Nov; 16(22):6702-12. PubMed ID: 9362485
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cloning of a novel prolyl 4-hydroxylase subunit expressed in the fibrous cap of human atherosclerotic plaque.
    Van Den Diepstraten C; Papay K; Bolender Z; Brown A; Pickering JG
    Circulation; 2003 Aug; 108(5):508-11. PubMed ID: 12874193
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Cell-free synthesis and assembly of prolyl 4-hydroxylase: the role of the beta-subunit (PDI) in preventing misfolding and aggregation of the alpha-subunit.
    John DC; Grant ME; Bulleid NJ
    EMBO J; 1993 Apr; 12(4):1587-95. PubMed ID: 8385607
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structure and expression of the human gene for the alpha subunit of prolyl 4-hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissues.
    Helaakoski T; Veijola J; Vuori K; Rehn M; Chow LT; Taillon-Miller P; Kivirikko KI; Pihlajaniemi T
    J Biol Chem; 1994 Nov; 269(45):27847-54. PubMed ID: 7961714
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Differences in collagen prolyl 4-hydroxylase assembly between two Caenorhabditis nematode species despite high amino acid sequence identity of the enzyme subunits.
    Winter AD; Keskiaho K; Kukkola L; McCormack G; Felix MA; Myllyharju J; Page AP
    Matrix Biol; 2007 Jun; 26(5):382-95. PubMed ID: 17321733
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Protein disulfide-isomerase retains procollagen prolyl 4-hydroxylase structure in its native conformation.
    Koivu J; Myllylä R
    Biochemistry; 1986 Oct; 25(20):5982-6. PubMed ID: 3024699
    [TBL] [Abstract][Full Text] [Related]  

  • 37. High-level production of human collagen prolyl 4-hydroxylase in Escherichia coli.
    Neubauer A; Neubauer P; Myllyharju J
    Matrix Biol; 2005 Feb; 24(1):59-68. PubMed ID: 15749002
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in Km values for peptide substrates with increasing chain length: mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half.
    Kukkola L; Koivunen P; Pakkanen O; Page AP; Myllyharju J
    J Biol Chem; 2004 Apr; 279(18):18656-61. PubMed ID: 14985345
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The structural motifs for substrate binding and dimerization of the α subunit of collagen prolyl 4-hydroxylase.
    Anantharajan J; Koski MK; Kursula P; Hieta R; Bergmann U; Myllyharju J; Wierenga RK
    Structure; 2013 Dec; 21(12):2107-18. PubMed ID: 24207127
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Site-directed mutagenesis of the alpha subunit of human prolyl 4-hydroxylase. Identification of three histidine residues critical for catalytic activity.
    Lamberg A; Pihlajaniemi T; Kivirikko KI
    J Biol Chem; 1995 Apr; 270(17):9926-31. PubMed ID: 7730375
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.