614 related articles for article (PubMed ID: 7756983)
1. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Vijayalakshmi J; Padmanabhan KP; Mann KG; Tulinsky A
Protein Sci; 1994 Dec; 3(12):2254-71. PubMed ID: 7756983
[TBL] [Abstract][Full Text] [Related]
2. Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.
Skrzypczak-Jankun E; Carperos VE; Ravichandran KG; Tulinsky A; Westbrook M; Maraganore JM
J Mol Biol; 1991 Oct; 221(4):1379-93. PubMed ID: 1942057
[TBL] [Abstract][Full Text] [Related]
3. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Bode W; Turk D; Karshikov A
Protein Sci; 1992 Apr; 1(4):426-71. PubMed ID: 1304349
[TBL] [Abstract][Full Text] [Related]
4. Proteolytic formation of either of the two prothrombin activation intermediates results in formation of a hirugen-binding site.
Liu LW; Ye J; Johnson AE; Esmon CT
J Biol Chem; 1991 Dec; 266(35):23633-6. PubMed ID: 1748641
[TBL] [Abstract][Full Text] [Related]
5. Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
Mochalkin I; Tulinsky A
Acta Crystallogr D Biol Crystallogr; 1999 Apr; 55(Pt 4):785-93. PubMed ID: 10089309
[TBL] [Abstract][Full Text] [Related]
6. Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Arni RK; Padmanabhan K; Padmanabhan KP; Wu TP; Tulinsky A
Biochemistry; 1993 May; 32(18):4727-37. PubMed ID: 8387813
[TBL] [Abstract][Full Text] [Related]
7. Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.
Qiu X; Padmanabhan KP; Carperos VE; Tulinsky A; Kline T; Maraganore JM; Fenton JW
Biochemistry; 1992 Dec; 31(47):11689-97. PubMed ID: 1445905
[TBL] [Abstract][Full Text] [Related]
8. The structure of a designed peptidomimetic inhibitor complex of alpha-thrombin.
Wu TP; Yee V; Tulinsky A; Chrusciel RA; Nakanishi H; Shen R; Priebe C; Kahn M
Protein Eng; 1993 Jul; 6(5):471-8. PubMed ID: 8415574
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution.
Chen Z; Li Y; Mulichak AM; Lewis SD; Shafer JA
Arch Biochem Biophys; 1995 Sep; 322(1):198-203. PubMed ID: 7574675
[TBL] [Abstract][Full Text] [Related]
10. Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin.
Ganesh V; Lee AY; Clardy J; Tulinsky A
Protein Sci; 1996 May; 5(5):825-35. PubMed ID: 8732754
[TBL] [Abstract][Full Text] [Related]
11. The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity.
Ye J; Liu LW; Esmon CT; Johnson AE
J Biol Chem; 1992 Jun; 267(16):11023-8. PubMed ID: 1317850
[TBL] [Abstract][Full Text] [Related]
12. New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK.
Martin PD; Malkowski MG; Box J; Esmon CT; Edwards BF
Structure; 1997 Dec; 5(12):1681-93. PubMed ID: 9438869
[TBL] [Abstract][Full Text] [Related]
13. Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
Nardini M; Pesce A; Rizzi M; Casale E; Ferraccioli R; Balliano G; Milla P; Ascenzi P; Bolognesi M
J Mol Biol; 1996 May; 258(5):851-9. PubMed ID: 8637015
[TBL] [Abstract][Full Text] [Related]
14. Allosteric changes in solvent accessibility observed in thrombin upon active site occupation.
Croy CH; Koeppe JR; Bergqvist S; Komives EA
Biochemistry; 2004 May; 43(18):5246-55. PubMed ID: 15122890
[TBL] [Abstract][Full Text] [Related]
15. The COOH-terminal domain of hirudin. An exosite-directed competitive inhibitor of the action of alpha-thrombin on fibrinogen.
Naski MC; Fenton JW; Maraganore JM; Olson ST; Shafer JA
J Biol Chem; 1990 Aug; 265(23):13484-9. PubMed ID: 2380171
[TBL] [Abstract][Full Text] [Related]
16. Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090.
Malley MF; Tabernero L; Chang CY; Ohringer SL; Roberts DG; Das J; Sack JS
Protein Sci; 1996 Feb; 5(2):221-8. PubMed ID: 8745399
[TBL] [Abstract][Full Text] [Related]
17. Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
Qiu X; Yin M; Padmanabhan KP; Krstenansky JL; Tulinsky A
J Biol Chem; 1993 Sep; 268(27):20318-26. PubMed ID: 8376390
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
Féthière J; Tsuda Y; Coulombe R; Konishi Y; Cygler M
Protein Sci; 1996 Jun; 5(6):1174-83. PubMed ID: 8762149
[TBL] [Abstract][Full Text] [Related]
19. Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1.
Krishnan R; Mochalkin I; Arni R; Tulinsky A
Acta Crystallogr D Biol Crystallogr; 2000 Mar; 56(Pt 3):294-303. PubMed ID: 10713516
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6.
Zdanov A; Wu S; DiMaio J; Konishi Y; Li Y; Wu X; Edwards BF; Martin PD; Cygler M
Proteins; 1993 Nov; 17(3):252-65. PubMed ID: 8272424
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
