These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 7763308)

  • 21. Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics.
    Hermans JJ; Thijssen HH
    Br J Pharmacol; 1993 Sep; 110(1):482-90. PubMed ID: 8220911
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
    Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase.
    Crespi CL; Miller VP
    Pharmacogenetics; 1997 Jun; 7(3):203-10. PubMed ID: 9241660
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Stereoselective N-demethylation of chlorpheniramine by rat-liver microsomes and the involvement of cytochrome P450 isozymes.
    Nomura A; Sakurai E; Hikichi N
    J Pharm Pharmacol; 1997 Mar; 49(3):257-62. PubMed ID: 9231341
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Monkey liver cytochrome P450 2C19 is involved in R- and S-warfarin 7-hydroxylation.
    Hosoi Y; Uno Y; Murayama N; Fujino H; Shukuya M; Iwasaki K; Shimizu M; Utoh M; Yamazaki H
    Biochem Pharmacol; 2012 Dec; 84(12):1691-5. PubMed ID: 23041648
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil.
    Tracy TS; Korzekwa KR; Gonzalez FJ; Wainer IW
    Br J Clin Pharmacol; 1999 May; 47(5):545-52. PubMed ID: 10336579
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Metabolite intermediate complexation of microsomal cytochrome P450 2C11 in male rat liver by nortriptyline.
    Murray M
    Mol Pharmacol; 1992 Nov; 42(5):931-8. PubMed ID: 1435757
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions.
    Rettie AE; Korzekwa KR; Kunze KL; Lawrence RF; Eddy AC; Aoyama T; Gelboin HV; Gonzalez FJ; Trager WF
    Chem Res Toxicol; 1992; 5(1):54-9. PubMed ID: 1581537
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
    Nakajima M; Inoue T; Shimada N; Tokudome S; Yamamoto T; Kuroiwa Y
    Drug Metab Dispos; 1998 Mar; 26(3):261-6. PubMed ID: 9492390
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model.
    Hutzler JM; Hauer MJ; Tracy TS
    Drug Metab Dispos; 2001 Jul; 29(7):1029-34. PubMed ID: 11408370
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes.
    Komatsu T; Yamazaki H; Shimada N; Nakajima M; Yokoi T
    Drug Metab Dispos; 2000 Dec; 28(12):1457-63. PubMed ID: 11095583
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Human liver cytochrome P450 enzymes involved in the 7-hydroxylation of R- and S-warfarin enantiomers.
    Yamazaki H; Shimada T
    Biochem Pharmacol; 1997 Dec; 54(11):1195-203. PubMed ID: 9416970
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily.
    Veronese ME; Doecke CJ; Mackenzie PI; McManus ME; Miners JO; Rees DL; Gasser R; Meyer UA; Birkett DJ
    Biochem J; 1993 Jan; 289 ( Pt 2)(Pt 2):533-8. PubMed ID: 8424795
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.
    Miyazawa M; Shindo M; Shimada T
    Drug Metab Dispos; 2002 May; 30(5):602-7. PubMed ID: 11950794
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Comparisons between in-vitro and in-vivo metabolism of (S)-warfarin: catalytic activities of cDNA-expressed CYP2C9, its Leu359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes.
    Takahashi H; Kashima T; Nomoto S; Iwade K; Tainaka H; Shimizu T; Nomizo Y; Muramoto N; Kimura S; Echizen H
    Pharmacogenetics; 1998 Oct; 8(5):365-73. PubMed ID: 9825828
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole.
    Uehara S; Uno Y; Inoue T; Kawano M; Shimizu M; Toda A; Utoh M; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2015 Oct; 43(10):1408-16. PubMed ID: 26228688
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways.
    Bort R; Macé K; Boobis A; Gómez-Lechón MJ; Pfeifer A; Castell J
    Biochem Pharmacol; 1999 Sep; 58(5):787-96. PubMed ID: 10449188
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
    Shen S; Marchick MR; Davis MR; Doss GA; Pohl LR
    Chem Res Toxicol; 1999 Feb; 12(2):214-22. PubMed ID: 10027801
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Pharm Sci; 1998 Jul; 87(7):845-53. PubMed ID: 9649353
    [TBL] [Abstract][Full Text] [Related]  

  • 40. 16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5.
    Huang Z; Guengerich FP; Kaminsky LS
    Carcinogenesis; 1998 May; 19(5):867-72. PubMed ID: 9635876
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.