BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 7763333)

  • 1. beta-Amyloid, protein processing and Alzheimer's disease.
    Haas C; Hung AY; Citron M; Teplow DB; Selkoe DJ
    Arzneimittelforschung; 1995 Mar; 45(3A):398-402. PubMed ID: 7763333
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Recent advances in Alzheimer's disease research--amyloid precursor protein trafficking, processing, and mutations in Alzheimer's disease linked genes].
    Fukatsu R; Tsuzuki K; Hayashi Y; Takamaru Y; Sasaki N; Yoshida T; Hatakeyama Y; Fuji N; Takahata N
    Hokkaido Igaku Zasshi; 1997 Jan; 72(1):3-11. PubMed ID: 9086357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.
    Citron M; Eckman CB; Diehl TS; Corcoran C; Ostaszewski BL; Xia W; Levesque G; St George Hyslop P; Younkin SG; Selkoe DJ
    Neurobiol Dis; 1998 Aug; 5(2):107-16. PubMed ID: 9746908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic background regulates beta-amyloid precursor protein processing and beta-amyloid deposition in the mouse.
    Lehman EJ; Kulnane LS; Gao Y; Petriello MC; Pimpis KM; Younkin L; Dolios G; Wang R; Younkin SG; Lamb BT
    Hum Mol Genet; 2003 Nov; 12(22):2949-56. PubMed ID: 14506131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.
    Haass C; Koo EH; Mellon A; Hung AY; Selkoe DJ
    Nature; 1992 Jun; 357(6378):500-3. PubMed ID: 1608449
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J; Ray WJ; Espeseth A; Simon A; Shi XP; Wolffe C; Getty K; Marine S; Stec E; Ferrer M; Strulovici B; Bartz S; Gates A; Xu M; Huang Q; Ma L; Shughrue P; Burchard J; Colussi D; Pietrak B; Kahana J; Beher D; Rosahl T; Shearman M; Hazuda D; Sachs AB; Koblan KS; Seabrook GR; Stone DJ
    Proc Natl Acad Sci U S A; 2006 Nov; 103(47):17967-72. PubMed ID: 17098871
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T; Kiliaan AJ; Kadish I
    Neurobiol Dis; 2006 Sep; 23(3):653-62. PubMed ID: 16829076
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta40.
    van Dijk R; Fischer DF; Sluijs JA; Sonnemans MA; Hobo B; Mercken L; Mann DM; Hol EM; van Leeuwen FW
    J Neurochem; 2004 Aug; 90(3):712-23. PubMed ID: 15255950
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
    J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Advances in molecular biology and clinical study of amyloid precursor protein for Alzheimer's disease].
    Xu BG; Wu X
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2004 Apr; 26(2):201-9. PubMed ID: 15171563
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Missense mutations associated with familial Alzheimer's disease in Sweden lead to the production of the amyloid peptide without internalization of its precursor.
    Essalmani R; Macq AF; Mercken L; Octave JN
    Biochem Biophys Res Commun; 1996 Jan; 218(1):89-96. PubMed ID: 8573182
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Beta-amyloid controls altered Reelin expression and processing in Alzheimer's disease.
    Botella-López A; Cuchillo-Ibáñez I; Cotrufo T; Mok SS; Li QX; Barquero MS; Dierssen M; Soriano E; Sáez-Valero J
    Neurobiol Dis; 2010 Mar; 37(3):682-91. PubMed ID: 20025970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The beta amyloid protein precursor: mRNAs, membrane-associated forms, and soluble derivatives.
    Palmert MR; Podlisny MB; Golde TE; Cohen ML; Kovacs DM; Tanzi RE; Gusella JF; Whitehouse PJ; Witker DS; Oltersdorf T
    Prog Clin Biol Res; 1989; 317():971-84. PubMed ID: 2513588
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
    Le Brocque D; Henry A; Cappai R; Li QX; Tanner JE; Galatis D; Gray C; Holmes S; Underwood JR; Beyreuther K; Masters CL; Evin G
    Biochemistry; 1998 Oct; 37(42):14958-65. PubMed ID: 9778373
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.
    Wang PL; Niidome T; Akaike A; Kihara T; Sugimoto H
    J Neurosci Res; 2009 Jul; 87(9):2105-14. PubMed ID: 19267423
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Brain site-specific gene expression analysis in Alzheimer's disease patients.
    Yokota T; Mishra M; Akatsu H; Tani Y; Miyauchi T; Yamamoto T; Kosaka K; Nagai Y; Sawada T; Heese K
    Eur J Clin Invest; 2006 Nov; 36(11):820-30. PubMed ID: 17032350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Molecular biology of beta A4 protein and Alzheimer disease].
    Charnay Y; Vallet PG; Giannakopoulos P; Hof PR; Bouras C
    Rev Neurol (Paris); 1994; 150(6-7):405-12. PubMed ID: 7747007
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intracellular copper deficiency increases amyloid-beta secretion by diverse mechanisms.
    Cater MA; McInnes KT; Li QX; Volitakis I; La Fontaine S; Mercer JF; Bush AI
    Biochem J; 2008 May; 412(1):141-52. PubMed ID: 18248325
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.