These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei. Carter NS; Berger BJ; Fairlamb AH J Biol Chem; 1995 Nov; 270(47):28153-7. PubMed ID: 7499305 [TBL] [Abstract][Full Text] [Related]
3. Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter. de Koning HP; Jarvis SM Acta Trop; 2001 Dec; 80(3):245-50. PubMed ID: 11700182 [TBL] [Abstract][Full Text] [Related]
4. Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei. Matovu E; Stewart ML; Geiser F; Brun R; Mäser P; Wallace LJ; Burchmore RJ; Enyaru JC; Barrett MP; Kaminsky R; Seebeck T; de Koning HP Eukaryot Cell; 2003 Oct; 2(5):1003-8. PubMed ID: 14555482 [TBL] [Abstract][Full Text] [Related]
5. Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites. Scott AG; Tait A; Turner CM Exp Parasitol; 1997 Jul; 86(3):181-90. PubMed ID: 9225768 [TBL] [Abstract][Full Text] [Related]
6. Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals. De Koning HP Mol Pharmacol; 2001 Mar; 59(3):586-92. PubMed ID: 11179454 [TBL] [Abstract][Full Text] [Related]
7. Pentamidine transport and sensitivity in brucei-group trypanosomes. Damper D; Patton CL J Protozool; 1976 May; 23(2):349-56. PubMed ID: 6797 [TBL] [Abstract][Full Text] [Related]
8. Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism. Fairlamb AH; Carter NS; Cunningham M; Smith K Mol Biochem Parasitol; 1992 Jul; 53(1-2):213-22. PubMed ID: 1501641 [TBL] [Abstract][Full Text] [Related]
9. Effects of intermediates of methionine metabolism and nucleoside analogs on S-adenosylmethionine transport by Trypanosoma brucei brucei and a drug-resistant Trypanosoma brucei rhodesiense. Goldberg B; Rattendi D; Lloyd D; Sufrin JR; Bacchi CJ Biochem Pharmacol; 1998 Jul; 56(1):95-103. PubMed ID: 9698093 [TBL] [Abstract][Full Text] [Related]
10. A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity. Barrett MP; Zhang ZQ; Denise H; Giroud C; Baltz T Mol Biochem Parasitol; 1995 Jul; 73(1-2):223-9. PubMed ID: 8577330 [TBL] [Abstract][Full Text] [Related]
11. Polyamine and pentamidine metabolism in African trypanosomes. Berger BJ; Carter NS; Fairlamb AH Acta Trop; 1993 Sep; 54(3-4):215-24. PubMed ID: 7902659 [TBL] [Abstract][Full Text] [Related]
12. Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense. Frommel TO; Balber AE Mol Biochem Parasitol; 1987 Nov; 26(1-2):183-91. PubMed ID: 3431564 [TBL] [Abstract][Full Text] [Related]
13. Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Alghamdi AH; Munday JC; Campagnaro GD; Gurvic D; Svensson F; Okpara CE; Kumar A; Quintana J; Martin Abril ME; Milić P; Watson L; Paape D; Settimo L; Dimitriou A; Wielinska J; Smart G; Anderson LF; Woodley CM; Kelly SPY; Ibrahim HM; Hulpia F; Al-Salabi MI; Eze AA; Sprenger T; Teka IA; Gudin S; Weyand S; Field M; Dardonville C; Tidwell RR; Carrington M; O'Neill P; Boykin DW; Zachariae U; De Koning HP Elife; 2020 Aug; 9():. PubMed ID: 32762841 [TBL] [Abstract][Full Text] [Related]
14. Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance. Lanteri CA; Stewart ML; Brock JM; Alibu VP; Meshnick SR; Tidwell RR; Barrett MP Mol Pharmacol; 2006 Nov; 70(5):1585-92. PubMed ID: 16912218 [TBL] [Abstract][Full Text] [Related]
15. Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. Munday JC; Eze AA; Baker N; Glover L; Clucas C; Aguinaga Andrés D; Natto MJ; Teka IA; McDonald J; Lee RS; Graf FE; Ludin P; Burchmore RJ; Turner CM; Tait A; MacLeod A; Mäser P; Barrett MP; Horn D; De Koning HP J Antimicrob Chemother; 2014 Mar; 69(3):651-63. PubMed ID: 24235095 [TBL] [Abstract][Full Text] [Related]
16. A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats. Anene BM; Ezeokonkwo RC; Mmesirionye TI; Tettey JN; Brock JM; Barrett MP; De Koning HP Parasitology; 2006 Jan; 132(Pt 1):127-33. PubMed ID: 16393361 [TBL] [Abstract][Full Text] [Related]
17. Induction of resistance to melarsenoxide cysteamine (Mel Cy) in Trypanosoma brucei brucei. Pospichal H; Brun R; Kaminsky R; Jenni L Acta Trop; 1994 Dec; 58(3-4):187-97. PubMed ID: 7709858 [TBL] [Abstract][Full Text] [Related]
18. Molecular pharmacology of adenosine transport in Trypanosoma brucei: P1/P2 revisited. Geiser F; Lüscher A; de Koning HP; Seebeck T; Mäser P Mol Pharmacol; 2005 Sep; 68(3):589-95. PubMed ID: 15933219 [TBL] [Abstract][Full Text] [Related]
19. Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol. Graf FE; Ludin P; Wenzler T; Kaiser M; Brun R; Pyana PP; Büscher P; de Koning HP; Horn D; Mäser P PLoS Negl Trop Dis; 2013; 7(10):e2475. PubMed ID: 24130910 [TBL] [Abstract][Full Text] [Related]
20. The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes. Teka IA; Kazibwe AJ; El-Sabbagh N; Al-Salabi MI; Ward CP; Eze AA; Munday JC; Mäser P; Matovu E; Barrett MP; de Koning HP Mol Pharmacol; 2011 Jul; 80(1):110-6. PubMed ID: 21436312 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]