795 related articles for article (PubMed ID: 7774014)
1. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase.
Franke TF; Yang SI; Chan TO; Datta K; Kazlauskas A; Morrison DK; Kaplan DR; Tsichlis PN
Cell; 1995 Jun; 81(5):727-36. PubMed ID: 7774014
[TBL] [Abstract][Full Text] [Related]
2. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation.
King WG; Mattaliano MD; Chan TO; Tsichlis PN; Brugge JS
Mol Cell Biol; 1997 Aug; 17(8):4406-18. PubMed ID: 9234699
[TBL] [Abstract][Full Text] [Related]
3. Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling.
Yu JC; Gutkind JS; Mahadevan D; Li W; Meyers KA; Pierce JH; Heidaran MA
J Cell Biol; 1994 Oct; 127(2):479-87. PubMed ID: 7929590
[TBL] [Abstract][Full Text] [Related]
4. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction.
Burgering BM; Coffer PJ
Nature; 1995 Aug; 376(6541):599-602. PubMed ID: 7637810
[TBL] [Abstract][Full Text] [Related]
5. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.
Kennedy SG; Wagner AJ; Conzen SD; Jordán J; Bellacosa A; Tsichlis PN; Hay N
Genes Dev; 1997 Mar; 11(6):701-13. PubMed ID: 9087425
[TBL] [Abstract][Full Text] [Related]
6. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate.
Franke TF; Kaplan DR; Cantley LC; Toker A
Science; 1997 Jan; 275(5300):665-8. PubMed ID: 9005852
[TBL] [Abstract][Full Text] [Related]
7. Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase.
Didichenko SA; Tilton B; Hemmings BA; Ballmer-Hofer K; Thelen M
Curr Biol; 1996 Oct; 6(10):1271-8. PubMed ID: 8939574
[TBL] [Abstract][Full Text] [Related]
8. The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells.
Chaudhary LR; Hruska KA
J Cell Biochem; 2001 Mar; 81(2):304-11. PubMed ID: 11241670
[TBL] [Abstract][Full Text] [Related]
9. Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.
van Weering DH; de Rooij J; Marte B; Downward J; Bos JL; Burgering BM
Mol Cell Biol; 1998 Apr; 18(4):1802-11. PubMed ID: 9528752
[TBL] [Abstract][Full Text] [Related]
10. Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt.
Cartel NJ; Wang J; Post M
Biochem J; 2002 Apr; 363(Pt 1):19-28. PubMed ID: 11903042
[TBL] [Abstract][Full Text] [Related]
11. Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells.
Sasaoka T; Kikuchi K; Wada T; Sato A; Hori H; Murakami S; Fukui K; Ishihara H; Aota R; Kimura I; Kobayashi M
Endocrinology; 2003 Sep; 144(9):4204-14. PubMed ID: 12933696
[TBL] [Abstract][Full Text] [Related]
12. The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.
Shimamura H; Terada Y; Okado T; Tanaka H; Inoshita S; Sasaki S
J Am Soc Nephrol; 2003 Jun; 14(6):1427-34. PubMed ID: 12761242
[TBL] [Abstract][Full Text] [Related]
13. Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.
Klotz LO; Schieke SM; Sies H; Holbrook NJ
Biochem J; 2000 Nov; 352 Pt 1(Pt 1):219-25. PubMed ID: 11062076
[TBL] [Abstract][Full Text] [Related]
14. Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase.
Konishi H; Matsuzaki H; Tanaka M; Ono Y; Tokunaga C; Kuroda S; Kikkawa U
Proc Natl Acad Sci U S A; 1996 Jul; 93(15):7639-43. PubMed ID: 8755528
[TBL] [Abstract][Full Text] [Related]
15. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.
Crowder RJ; Freeman RS
J Neurosci; 1998 Apr; 18(8):2933-43. PubMed ID: 9526010
[TBL] [Abstract][Full Text] [Related]
16. Platelet-derived growth factor activates porcine thecal cell phosphatidylinositol-3-kinase-Akt/PKB and ras-extracellular signal-regulated kinase-1/2 kinase signaling pathways via the platelet-derived growth factor-beta receptor.
Taylor CC
Endocrinology; 2000 Apr; 141(4):1545-53. PubMed ID: 10746662
[TBL] [Abstract][Full Text] [Related]
17. AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells.
Liu AX; Testa JR; Hamilton TC; Jove R; Nicosia SV; Cheng JQ
Cancer Res; 1998 Jul; 58(14):2973-7. PubMed ID: 9679957
[TBL] [Abstract][Full Text] [Related]
18. Phosphatidylinositol 3-kinase activity is required for the activation process of focal adhesion kinase by platelet-derived growth factor.
Saito Y; Mori S; Yokote K; Kanzaki T; Saito Y; Morisaki N
Biochem Biophys Res Commun; 1996 Jul; 224(1):23-6. PubMed ID: 8694818
[TBL] [Abstract][Full Text] [Related]
19. Evidence for phosphatidylinositol 3-kinase-Akt-p7S6K pathway activation and transduction of mitogenic signals by platelet-derived growth factor in meningioma cells.
Johnson MD; Okedli E; Woodard A; Toms SA; Allen GS
J Neurosurg; 2002 Sep; 97(3):668-75. PubMed ID: 12296652
[TBL] [Abstract][Full Text] [Related]
20. Cell adhesion regulates platelet-derived growth factor-induced MAP kinase and PI-3 kinase activation in stellate cells.
Carloni V; Defranco RM; Caligiuri A; Gentilini A; Sciammetta SC; Baldi E; Lottini B; Gentilini P; Pinzani M
Hepatology; 2002 Sep; 36(3):582-91. PubMed ID: 12198650
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]