356 related articles for article (PubMed ID: 7780976)
1. Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo.
Moritz T; Mackay W; Glassner BJ; Williams DA; Samson L
Cancer Res; 1995 Jun; 55(12):2608-14. PubMed ID: 7780976
[TBL] [Abstract][Full Text] [Related]
2. Reversal of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced severe immunodeficiency by transduction of murine long-lived hemopoietic progenitor cells using O6-methylguanine DNA methyltransferase complementary DNA.
Maze R; Kapur R; Kelley MR; Hansen WK; Oh SY; Williams DA
J Immunol; 1997 Jan; 158(2):1006-13. PubMed ID: 8993023
[TBL] [Abstract][Full Text] [Related]
3. Human alkyltransferase-transduced murine myeloid progenitors are enriched in vivo by BCNU treatment of transplanted mice.
Allay JA; Davis BM; Gerson SL
Exp Hematol; 1997 Sep; 25(10):1069-76. PubMed ID: 9293904
[TBL] [Abstract][Full Text] [Related]
4. Retrovirus-mediated expression of the base excision repair proteins, formamidopyrimidine DNA glycosylase or human oxoguanine DNA glycosylase, protects hematopoietic cells from N,N',N"-triethylenethiophosphoramide (thioTEPA)-induced toxicity in vitro and in vivo.
Kobune M; Xu Y; Baum C; Kelley MR; Williams DA
Cancer Res; 2001 Jul; 61(13):5116-25. PubMed ID: 11431349
[TBL] [Abstract][Full Text] [Related]
5. Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.
Reese JS; Roth JC; Gerson SL
Stem Cells; 2008 Mar; 26(3):675-81. PubMed ID: 18192231
[TBL] [Abstract][Full Text] [Related]
6. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
Ragg S; Xu-Welliver M; Bailey J; D'Souza M; Cooper R; Chandra S; Seshadri R; Pegg AE; Williams DA
Cancer Res; 2000 Sep; 60(18):5187-95. PubMed ID: 11016647
[TBL] [Abstract][Full Text] [Related]
7. Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.
Kramer BA; Lemckert FA; Alexander IE; Gunning PW; McCowage GB
J Gene Med; 2006 Sep; 8(9):1071-85. PubMed ID: 16927363
[TBL] [Abstract][Full Text] [Related]
8. Retroviral-mediated gene transduction of human alkyltransferase complementary DNA confers nitrosourea resistance to human hematopoietic progenitors.
Allay JA; Koç ON; Davis BM; Gerson SL
Clin Cancer Res; 1996 Aug; 2(8):1353-9. PubMed ID: 9816307
[TBL] [Abstract][Full Text] [Related]
9. Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells.
Jansen M; Sorg UR; Ragg S; Flasshove M; Seeber S; Williams DA; Moritz T
Cancer Gene Ther; 2002 Sep; 9(9):737-46. PubMed ID: 12189523
[TBL] [Abstract][Full Text] [Related]
10. Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent.
Maze R; Carney JP; Kelley MR; Glassner BJ; Williams DA; Samson L
Proc Natl Acad Sci U S A; 1996 Jan; 93(1):206-10. PubMed ID: 8552605
[TBL] [Abstract][Full Text] [Related]
11. Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase.
Dumenco LL; Warman B; Hatzoglou M; Lim IK; Abboud SL; Gerson SL
Cancer Res; 1989 Nov; 49(21):6044-51. PubMed ID: 2676154
[TBL] [Abstract][Full Text] [Related]
12. Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Davis BM; Reese JS; Koç ON; Lee K; Schupp JE; Gerson SL
Cancer Res; 1997 Nov; 57(22):5093-9. PubMed ID: 9371508
[TBL] [Abstract][Full Text] [Related]
13. Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells.
Allay JA; Dumenco LL; Koc ON; Liu L; Gerson SL
Blood; 1995 Jun; 85(11):3342-51. PubMed ID: 7756667
[TBL] [Abstract][Full Text] [Related]
14. Retroviral coexpression of two different types of drug resistance genes to protect normal cells from combination chemotherapy.
Suzuki M; Sugimoto Y; Tsukahara S; Okochi E; Gottesman MM; Tsuruo T
Clin Cancer Res; 1997 Jun; 3(6):947-54. PubMed ID: 9815770
[TBL] [Abstract][Full Text] [Related]
15. Retrovirus-mediated transfer of the human O6-methylguanine-DNA methyltransferase gene into a murine hematopoietic stem cell line and resistance to the toxic effects of certain alkylating agents.
Wang G; Weiss C; Sheng P; Bresnick E
Biochem Pharmacol; 1996 May; 51(9):1221-8. PubMed ID: 8645346
[TBL] [Abstract][Full Text] [Related]
16. A bicistronic SIN-lentiviral vector containing G156A MGMT allows selection and metabolic correction of hematopoietic protoporphyric cell lines.
Richard E; Géronimi F; Lalanne M; Ged C; Redonnet-Vernhet I; Lamrissi-Garcia I; Gerson SL; de Verneuil H; Moreau-Gaudry F
J Gene Med; 2003 Sep; 5(9):737-47. PubMed ID: 12950064
[TBL] [Abstract][Full Text] [Related]
17. [In vitro study on transduction of human O(6)-methylguanine-DNA-methyltransferase cDNA into human umbilical cord blood CD34(+) cells].
Wang J; Xia X; Chen Z; Lu D; Xue J; Ruan C
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2000 Dec; 17(6):395-8. PubMed ID: 11110975
[TBL] [Abstract][Full Text] [Related]
18. Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection.
Roth TJ; Xu Y; Luo M; Kelley MR
Cancer Gene Ther; 2003 Aug; 10(8):603-10. PubMed ID: 12872142
[TBL] [Abstract][Full Text] [Related]
19. Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
Jansen M; Bardenheuer W; Sorg UR; Seeber S; Flasshove M; Moritz T
Eur J Haematol; 2001 Jul; 67(1):2-13. PubMed ID: 11553261
[TBL] [Abstract][Full Text] [Related]
20. Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.
Wu ZN; Chan CL; Eastman A; Bresnick E
Cancer Res; 1992 Jan; 52(1):32-5. PubMed ID: 1727384
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
