BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 7781602)

  • 1. Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.
    Chan AC; Dalton M; Johnson R; Kong GH; Wang T; Thoma R; Kurosaki T
    EMBO J; 1995 Jun; 14(11):2499-508. PubMed ID: 7781602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases.
    Wong J; Straus D; Chan AC
    Mol Cell Biol; 1998 May; 18(5):2855-66. PubMed ID: 9566904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.
    Walk SF; March ME; Ravichandran KS
    Eur J Immunol; 1998 Aug; 28(8):2265-75. PubMed ID: 9710204
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck.
    Pelosi M; Di Bartolo V; Mounier V; Mège D; Pascussi JM; Dufour E; Blondel A; Acuto O
    J Biol Chem; 1999 May; 274(20):14229-37. PubMed ID: 10318843
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding.
    Visco C; Magistrelli G; Bosotti R; Perego R; Rusconi L; Toma S; Zamai M; Acuto O; Isacchi A
    Biochemistry; 2000 Mar; 39(10):2784-91. PubMed ID: 10704231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain.
    Chan AC; Iwashima M; Turck CW; Weiss A
    Cell; 1992 Nov; 71(4):649-62. PubMed ID: 1423621
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling.
    Di Bartolo V; Mège D; Germain V; Pelosi M; Dufour E; Michel F; Magistrelli G; Isacchi A; Acuto O
    J Biol Chem; 1999 Mar; 274(10):6285-94. PubMed ID: 10037717
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Age-related impairments in TCR/CD3 activation of ZAP-70 are associated with reduced tyrosine phosphorylations of zeta-chains and p59fyn/p56lck in human T cells.
    Whisler RL; Chen M; Liu B; Newhouse YG
    Mech Ageing Dev; 1999 Nov; 111(1):49-66. PubMed ID: 10576607
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of Zap-70 by Src family tyrosine protein kinases in an antigen-specific T-cell line.
    Weil R; Cloutier JF; Fournel M; Veillette A
    J Biol Chem; 1995 Feb; 270(6):2791-9. PubMed ID: 7852351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.
    Williams BL; Irvin BJ; Sutor SL; Chini CC; Yacyshyn E; Bubeck Wardenburg J; Dalton M; Chan AC; Abraham RT
    EMBO J; 1999 Apr; 18(7):1832-44. PubMed ID: 10202147
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase.
    Latour S; Fournel M; Veillette A
    Mol Cell Biol; 1997 Aug; 17(8):4434-41. PubMed ID: 9234701
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases.
    Iwashima M; Irving BA; van Oers NS; Chan AC; Weiss A
    Science; 1994 Feb; 263(5150):1136-9. PubMed ID: 7509083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.
    Denny MF; Patai B; Straus DB
    Mol Cell Biol; 2000 Feb; 20(4):1426-35. PubMed ID: 10648627
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction.
    Wu J; Zhao Q; Kurosaki T; Weiss A
    J Exp Med; 1997 May; 185(10):1877-82. PubMed ID: 9151714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins.
    Neumeister EN; Zhu Y; Richard S; Terhorst C; Chan AC; Shaw AS
    Mol Cell Biol; 1995 Jun; 15(6):3171-8. PubMed ID: 7760813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells.
    van Leeuwen JE; Paik PK; Samelson LE
    Mol Cell Biol; 1999 Oct; 19(10):6652-64. PubMed ID: 10490604
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.
    Isakov N; Wange RL; Burgess WH; Watts JD; Aebersold R; Samelson LE
    J Exp Med; 1995 Jan; 181(1):375-80. PubMed ID: 7528772
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases.
    Brdicka T; Kadlecek TA; Roose JP; Pastuszak AW; Weiss A
    Mol Cell Biol; 2005 Jun; 25(12):4924-33. PubMed ID: 15923611
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.
    Kong G; Dalton M; Bubeck Wardenburg J; Straus D; Kurosaki T; Chan AC
    Mol Cell Biol; 1996 Sep; 16(9):5026-35. PubMed ID: 8756661
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Critical role of Ser-520 phosphorylation for membrane recruitment and activation of the ZAP-70 tyrosine kinase in T cells.
    Yang Y; Villain P; Mustelin T; Couture C
    Mol Cell Biol; 2003 Nov; 23(21):7667-77. PubMed ID: 14560012
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.