297 related articles for article (PubMed ID: 7783131)
1. Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles.
Perregaard J; Moltzen EK; Meier E; Sánchez C
J Med Chem; 1995 May; 38(11):1998-2008. PubMed ID: 7783131
[TBL] [Abstract][Full Text] [Related]
2. Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines.
Moltzen EK; Perregaard J; Meier E
J Med Chem; 1995 May; 38(11):2009-17. PubMed ID: 7783132
[TBL] [Abstract][Full Text] [Related]
3. Selective, centrally acting serotonin 5-HT2 antagonists. 2. Substituted 3-(4-fluorophenyl)-1H-indoles.
Andersen K; Perregaard J; Arnt J; Nielsen JB; Begtrup M
J Med Chem; 1992 Dec; 35(26):4823-31. PubMed ID: 1336054
[TBL] [Abstract][Full Text] [Related]
4. Selective, centrally acting serotonin 5-HT2 antagonists. 1. 2- and 6-substituted 1-phenyl-3-(4-piperidinyl)-1H-indoles.
Perregaard J; Andersen K; Hyttel J; Sánchez C
J Med Chem; 1992 Dec; 35(26):4813-22. PubMed ID: 1336053
[TBL] [Abstract][Full Text] [Related]
5. Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1.
Maier CA; Wünsch B
J Med Chem; 2002 Jan; 45(2):438-48. PubMed ID: 11784148
[TBL] [Abstract][Full Text] [Related]
6. Lu 28-179 labels a sigma(2)-site in rat and human brain.
Søby KK; Mikkelsen JD; Meier E; Thomsen C
Neuropharmacology; 2002 Jul; 43(1):95-100. PubMed ID: 12213263
[TBL] [Abstract][Full Text] [Related]
7. Substituted benzylaminoalkylindoles with preference for the sigma2 binding site.
Mamolo MG; Zampieri D; Zanette C; Florio C; Collina S; Urbano M; Azzolina O; Vio L
Eur J Med Chem; 2008 Oct; 43(10):2073-81. PubMed ID: 18069094
[TBL] [Abstract][Full Text] [Related]
8. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
Berardi F; Santoro S; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1998 Oct; 41(21):3940-7. PubMed ID: 9767631
[TBL] [Abstract][Full Text] [Related]
9. Serotonin 5-HT2 receptor, dopamine D2 receptor, and alpha 1 adrenoceptor antagonists. Conformationally flexible analogues of the atypical antipsychotic sertindole.
Andersen K; Liljefors T; Hyttel J; Perregaard J
J Med Chem; 1996 Sep; 39(19):3723-38. PubMed ID: 8809161
[TBL] [Abstract][Full Text] [Related]
10. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
11. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
Berardi F; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Oct; 39(21):4255-60. PubMed ID: 8863803
[TBL] [Abstract][Full Text] [Related]
12. The selective sigma2-ligand Lu 28-179 has potent anxiolytic-like effects in rodents.
Sánchez C; Arnt J; Costall B; Kelly ME; Meier E; Naylor RJ; Perregaard J
J Pharmacol Exp Ther; 1997 Dec; 283(3):1323-32. PubMed ID: 9400007
[TBL] [Abstract][Full Text] [Related]
13. NPC 16377, a potent and selective sigma-ligand. I. Receptor binding, neurochemical and neuroendocrine profile.
Karbon EW; Abreu ME; Erickson RH; Kaiser C; Natalie KJ; Clissold DB; Borosky S; Bailey M; Martin LA; Pontecorvo MJ
J Pharmacol Exp Ther; 1993 May; 265(2):866-75. PubMed ID: 8388461
[TBL] [Abstract][Full Text] [Related]
14. 3-(4-Piperidinyl)- and 3-(8-aza-bicyclo[3.2.1]oct-3-yl)-2-phenyl-1H-indoles as bioavailable h5-HT2A antagonists.
Crawforth J; Goodacre S; Maxey R; Bourrain S; Patel S; Marwood R; O'Connor D; Herbert R; Hutson P; Rowley M
Bioorg Med Chem Lett; 2000 Dec; 10(24):2701-3. PubMed ID: 11133072
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and pharmacological evaluation of indole-based sigma receptor ligands.
Mésangeau C; Amata E; Alsharif W; Seminerio MJ; Robson MJ; Matsumoto RR; Poupaert JH; McCurdy CR
Eur J Med Chem; 2011 Oct; 46(10):5154-61. PubMed ID: 21899931
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, configuration, and activity of isomeric 2-phenyl-2-(N-piperidinyl)bicyclo[3.1.0]hexanes at phencyclidine and sigma binding sites.
de Costa BR; Mattson MV; George C; Linders JT
J Med Chem; 1992 Dec; 35(25):4704-12. PubMed ID: 1469699
[TBL] [Abstract][Full Text] [Related]
17. [3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus.
Bonhaus DW; Loury DN; Jakeman LB; To Z; DeSouza A; Eglen RM; Wong EH
J Pharmacol Exp Ther; 1993 Nov; 267(2):961-70. PubMed ID: 8246171
[TBL] [Abstract][Full Text] [Related]
18. Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity.
Liu CZ; Mottinelli M; Nicholson HE; McVeigh BM; Wong NK; McCurdy CR; Bowen WD
Eur J Pharmacol; 2021 Sep; 906():174263. PubMed ID: 34144027
[TBL] [Abstract][Full Text] [Related]
19. A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites.
Berardi F; Ferorelli S; Colabufo NA; Leopoldo M; Perrone R; Tortorella V
Bioorg Med Chem; 2001 May; 9(5):1325-35. PubMed ID: 11377189
[TBL] [Abstract][Full Text] [Related]
20. Novel (4-phenylpiperidinyl)- and (4-phenylpiperazinyl)alkyl-spaced esters of 1-phenylcyclopentanecarboxylic acids as potent sigma-selective compounds.
Hudkins RL; Mailman RB; DeHaven-Hudkins DL
J Med Chem; 1994 Jun; 37(13):1964-70. PubMed ID: 8027978
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]