These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 7785058)

  • 1. Validation of an in vitro teratology system using chiral substances: stereoselective teratogenicity of 4-yn-valproic acid in cultured mouse embryos.
    Andrews JE; Ebron-McCoy M; Bojic U; Nau H; Kavlock RJ
    Toxicol Appl Pharmacol; 1995 Jun; 132(2):310-6. PubMed ID: 7785058
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analogue 2-N-propyl-4-pentynoic acid (4-yn-VPA): cross-species evaluation in whole embryo culture.
    Andrews JE; Ebron-McCoy MT; Bojic U; Nau H; Kavlock RJ
    Teratology; 1997 May; 55(5):314-8. PubMed ID: 9261925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The enantiomers of the valproic acid analogue 2-n-propyl-4-pentynoic acid (4-yn-VPA): asymmetric synthesis and highly stereoselective teratogenicity in mice.
    Hauck RS; Nau H
    Pharm Res; 1992 Jul; 9(7):850-5. PubMed ID: 1437995
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prediction of embryotoxic effects of valproic acid-derivatives with molecular in vitro methods.
    Lampen A; Göttlicher M; Nau H
    ALTEX; 2001; 18(2):123-6. PubMed ID: 11378687
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Valproic acid-induced neural tube defects in mouse and human: aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms.
    Nau H; Hauck RS; Ehlers K
    Pharmacol Toxicol; 1991 Nov; 69(5):310-21. PubMed ID: 1803343
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acid.
    Hauck RS; Nau H
    Toxicol Lett; 1989 Oct; 49(1):41-8. PubMed ID: 2510370
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The enantioselective teratogenicity of 2-n-propyl-4-pentynoic acid (4-yn-VPA) is due to stereoselective intrinsic activity and not differences in pharmacokinetics.
    Hauck RS; Elmazar MM; Plum C; Nau H
    Toxicol Lett; 1992 Apr; 60(2):145-53. PubMed ID: 1570629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prediction of teratogenic potency of valproate analogues using cerebellar aggregation cultures.
    Maar TE; Ellerbeck U; Bock E; Nau H; Schousboe A; Berezin V
    Toxicology; 1997 Jan; 116(1-3):159-68. PubMed ID: 9020517
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of varying potency.
    Bacon CL; Berezin V; Bode G; Bock E; Bojic U; Doherty P; Ehlers K; Ellerbeck U; Julien P; Kawa A; Maar TE; Nau H; Pirovano R; Regan CM; Schousboe A; Spezia F; Walsh FS; Williams EJ
    Toxicol In Vitro; 1998 Apr; 12(2):101-9. PubMed ID: 20654391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple effects of pentyl-4-yn-VPA enantiomers: from toxicity to short-term memory enhancement.
    Gotfryd K; Owczarek S; Hoffmann K; Klementiev B; Nau H; Berezin V; Bock E; Walmod PS
    Neuropharmacology; 2007 Mar; 52(3):764-78. PubMed ID: 17095022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential enantioselective effects of pentyl-4-yn-valproate on spatial learning in the rat, and neurite outgrowth and cyclin D3 expression in vitro.
    O'Loinsigh ED; Gherardini LM; Gallagher HC; Foley AG; Murphy KJ; Regan CM
    J Neurochem; 2004 Jan; 88(2):370-9. PubMed ID: 14690525
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells.
    Jergil M; Forsberg M; Salter H; Stockling K; Gustafson AL; Dencker L; Stigson M
    Toxicol Sci; 2011 Jun; 121(2):328-42. PubMed ID: 21427059
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Teratogenic effects of valproic acid and diphenylhydantoin on mouse embryos in culture.
    Bruckner A; Lee YJ; O'Shea KS; Henneberry RC
    Teratology; 1983 Feb; 27(1):29-42. PubMed ID: 6405496
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of valproic acid, some of its metabolites and analogues on prenatal development of rats in vitro and comparison with effects in vivo.
    Klug S; Lewandowski C; Zappel F; Merker HJ; Nau H; Neubert D
    Arch Toxicol; 1990; 64(7):545-53. PubMed ID: 2073128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Postimplantation whole embryo culture assay for hamsters: an alternative to rat and mouse.
    Wlodarczyk B; Biernacki B; Minta M; Zmudzki J
    ScientificWorldJournal; 2001 Jun; 1():227-34. PubMed ID: 12806092
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modified Xenopus laevis approach (R-FETAX) as an alternative test for the evaluation of foetal valproate spectrum disorder.
    Battistoni M; Bacchetta R; Di Renzo F; Metruccio F; Moretto A; Menegola E
    Reprod Toxicol; 2022 Jan; 107():140-149. PubMed ID: 34923091
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
    Okada A; Noyori H; Yagen B; Shimshoni JA; Bialer M; Fujiwara M
    Birth Defects Res B Dev Reprod Toxicol; 2009 Oct; 86(5):394-401. PubMed ID: 19830722
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid.
    Spiegelstein O; Yagen B; Levy RH; Finnell RH; Bennett GD; Roeder M; Schurig V; Bialer M
    Pharm Res; 1999 Oct; 16(10):1582-8. PubMed ID: 10554101
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New molecular bioassays for the estimation of the teratogenic potency of valproic acid derivatives in vitro: activation of the peroxisomal proliferator-activated receptor (PPARdelta).
    Lampen A; Siehler S; Ellerbeck U; Göttlicher M; Nau H
    Toxicol Appl Pharmacol; 1999 Nov; 160(3):238-49. PubMed ID: 10544058
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of teratogenicity of trans-2-ene-valproic acid compared to valproic acid in rats.
    Vorhees CV; Acuff-Smith KD; Weisenburger WP; Minck DR; Berry JS; Setchell KD; Nau H
    Teratology; 1991 Jun; 43(6):583-90. PubMed ID: 1882349
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.