BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 7791786)

  • 1. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
    Lu Q; Knoepfler PS; Scheele J; Wright DD; Kamps MP
    Mol Cell Biol; 1995 Jul; 15(7):3786-95. PubMed ID: 7791786
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1.
    Calvo KR; Knoepfler P; McGrath S; Kamps MP
    Oncogene; 1999 Dec; 18(56):8033-43. PubMed ID: 10637514
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1.
    Knoepfler PS; Calvo KR; Chen H; Antonarakis SE; Kamps MP
    Proc Natl Acad Sci U S A; 1997 Dec; 94(26):14553-8. PubMed ID: 9405651
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements.
    Knoepfler PS; Kamps MP
    Oncogene; 1997 May; 14(21):2521-31. PubMed ID: 9191052
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo.
    Lu Q; Kamps MP
    Oncogene; 1997 Jan; 14(1):75-83. PubMed ID: 9010234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Identification of proteins associated with transcription factors HOXA9 and E2A-PBX1 by tandem affinity purification].
    Shestakova EA; Boutin M; Bourassa S; Bonneil E; Bijl JJ
    Mol Biol (Mosk); 2017; 51(3):490-501. PubMed ID: 28707666
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.
    Chang CP; de Vivo I; Cleary ML
    Mol Cell Biol; 1997 Jan; 17(1):81-8. PubMed ID: 8972188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.
    Knoepfler PS; Kamps MP
    Mol Cell Biol; 1995 Oct; 15(10):5811-9. PubMed ID: 7565734
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.
    Chang CP; Shen WF; Rozenfeld S; Lawrence HJ; Largman C; Cleary ML
    Genes Dev; 1995 Mar; 9(6):663-74. PubMed ID: 7729685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex.
    Lu Q; Kamps MP
    Mol Cell Biol; 1996 Apr; 16(4):1632-40. PubMed ID: 8657138
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.
    Lu Q; Wright DD; Kamps MP
    Mol Cell Biol; 1994 Jun; 14(6):3938-48. PubMed ID: 7910944
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
    Monica K; LeBrun DP; Dedera DA; Brown R; Cleary ML
    Mol Cell Biol; 1994 Dec; 14(12):8304-14. PubMed ID: 7969166
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins.
    Chang CP; Jacobs Y; Nakamura T; Jenkins NA; Copeland NG; Cleary ML
    Mol Cell Biol; 1997 Oct; 17(10):5679-87. PubMed ID: 9315626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation.
    Kamps MP; Wright DD; Lu Q
    Oncogene; 1996 Jan; 12(1):19-30. PubMed ID: 8552391
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif.
    Phelan ML; Rambaldi I; Featherstone MS
    Mol Cell Biol; 1995 Aug; 15(8):3989-97. PubMed ID: 7623795
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1.
    Scheele JS; Kolanczyk M; Gantert M; Zemojtel T; Dorn A; Sykes DB; Möbest DC; Kamps MP; Räpple D
    Leuk Lymphoma; 2009 May; 50(5):816-28. PubMed ID: 19399691
    [TBL] [Abstract][Full Text] [Related]  

  • 17. E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice.
    Sykes DB; Kamps MP
    Mol Cell Biol; 2004 Feb; 24(3):1256-69. PubMed ID: 14729970
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1.
    Knoepfler PS; Bergstrom DA; Uetsuki T; Dac-Korytko I; Sun YH; Wright WE; Tapscott SJ; Kamps MP
    Nucleic Acids Res; 1999 Sep; 27(18):3752-61. PubMed ID: 10471746
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif.
    Knoepfler PS; Lu Q; Kamps MP
    Nucleic Acids Res; 1996 Jun; 24(12):2288-94. PubMed ID: 8710498
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2.
    van Dijk MA; Peltenburg LT; Murre C
    Mech Dev; 1995 Jul; 52(1):99-108. PubMed ID: 7577680
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.