BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 7803386)

  • 1. Structural consequences of redesigning a protein-zinc binding site.
    Ippolito JA; Christianson DW
    Biochemistry; 1994 Dec; 33(51):15241-9. PubMed ID: 7803386
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity.
    Lesburg CA; Huang C; Christianson DW; Fierke CA
    Biochemistry; 1997 Dec; 36(50):15780-91. PubMed ID: 9398308
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II.
    Huang CC; Lesburg CA; Kiefer LL; Fierke CA; Christianson DW
    Biochemistry; 1996 Mar; 35(11):3439-46. PubMed ID: 8639494
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
    Cox JD; Hunt JA; Compher KM; Fierke CA; Christianson DW
    Biochemistry; 2000 Nov; 39(45):13687-94. PubMed ID: 11076507
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-assisted redesign of a protein-zinc-binding site with femtomolar affinity.
    Ippolito JA; Baird TT; McGee SA; Christianson DW; Fierke CA
    Proc Natl Acad Sci U S A; 1995 May; 92(11):5017-21. PubMed ID: 7761440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of His94-->Asp carbonic anhydrase II in a new crystalline form reveals a partially occupied zinc binding site.
    Ippolito JA; Nair SK; Alexander RS; Kiefer LL; Fierke CA; Christianson DW
    Protein Eng; 1995 Oct; 8(10):975-80. PubMed ID: 8771178
    [TBL] [Abstract][Full Text] [Related]  

  • 7. X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis.
    Scolnick LR; Christianson DW
    Biochemistry; 1996 Dec; 35(51):16429-34. PubMed ID: 8987974
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metal binding specificity in carbonic anhydrase is influenced by conserved hydrophobic core residues.
    Hunt JA; Ahmed M; Fierke CA
    Biochemistry; 1999 Jul; 38(28):9054-62. PubMed ID: 10413479
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disruption of the active site solvent network in carbonic anhydrase II decreases the efficiency of proton transfer.
    Jackman JE; Merz KM; Fierke CA
    Biochemistry; 1996 Dec; 35(51):16421-8. PubMed ID: 8987973
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Zinc site redesign in T4 gene 32 protein: structure and stability of cobalt(II) complexes formed by wild-type and metal ligand substitution mutants.
    Guo J; Giedroc DP
    Biochemistry; 1997 Jan; 36(4):730-42. PubMed ID: 9020770
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of an engineered His3Cys zinc binding site in human carbonic anhydrase II.
    Ippolito JA; Christianson DW
    Biochemistry; 1993 Sep; 32(38):9901-5. PubMed ID: 8399159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Engineering the zinc binding site of human carbonic anhydrase II: structure of the His-94-->Cys apoenzyme in a new crystalline form.
    Alexander RS; Kiefer LL; Fierke CA; Christianson DW
    Biochemistry; 1993 Feb; 32(6):1510-8. PubMed ID: 8431430
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metal poison inhibition of carbonic anhydrase.
    Lindahl M; Svensson LA; Liljas A
    Proteins; 1993 Feb; 15(2):177-82. PubMed ID: 8441752
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
    Xue Y; Liljas A; Jonsson BH; Lindskog S
    Proteins; 1993 Sep; 17(1):93-106. PubMed ID: 7901850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Engineering a cysteine ligand into the zinc binding site of human carbonic anhydrase II.
    Kiefer LL; Krebs JF; Paterno SA; Fierke CA
    Biochemistry; 1993 Sep; 32(38):9896-900. PubMed ID: 8399158
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional characterization of human carbonic anhydrase II variants with altered zinc binding sites.
    Kiefer LL; Fierke CA
    Biochemistry; 1994 Dec; 33(51):15233-40. PubMed ID: 7803385
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cys(x)His(y)-Zn2+ interactions: thiol vs. thiolate coordination.
    Simonson T; Calimet N
    Proteins; 2002 Oct; 49(1):37-48. PubMed ID: 12211014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystallographic analysis of Thr-200-->His human carbonic anhydrase II and its complex with the substrate, HCO3-.
    Xue Y; Vidgren J; Svensson LA; Liljas A; Jonsson BH; Lindskog S
    Proteins; 1993 Jan; 15(1):80-7. PubMed ID: 8451242
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Refined 2.0 A X-ray crystal structure of the snake venom zinc-endopeptidase adamalysin II. Primary and tertiary structure determination, refinement, molecular structure and comparison with astacin, collagenase and thermolysin.
    Gomis-RĂ¼th FX; Kress LF; Kellermann J; Mayr I; Lee X; Huber R; Bode W
    J Mol Biol; 1994 Jun; 239(4):513-44. PubMed ID: 8006965
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Femtomolar Zn(II) affinity in a peptide-based ligand designed to model thiolate-rich metalloprotein active sites.
    Petros AK; Reddi AR; Kennedy ML; Hyslop AG; Gibney BR
    Inorg Chem; 2006 Dec; 45(25):9941-58. PubMed ID: 17140191
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.