BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 7806540)

  • 1. A mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation.
    Ouwens DM; van der Zon GC; Pronk GJ; Bos JL; Möller W; Cheatham B; Kahn CR; Maassen JA
    J Biol Chem; 1994 Dec; 269(52):33116-22. PubMed ID: 7806540
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation.
    Sasaoka T; Draznin B; Leitner JW; Langlois WJ; Olefsky JM
    J Biol Chem; 1994 Apr; 269(14):10734-8. PubMed ID: 8144662
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin receptor substrate-1 (IRS1) and Shc compete for a limited pool of Grb2 in mediating insulin downstream signaling.
    Yamauchi K; Pessin JE
    J Biol Chem; 1994 Dec; 269(49):31107-14. PubMed ID: 7983051
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras.
    Pronk GJ; de Vries-Smits AM; Buday L; Downward J; Maassen JA; Medema RH; Bos JL
    Mol Cell Biol; 1994 Mar; 14(3):1575-81. PubMed ID: 8114695
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes.
    Sharma PM; Son HS; Ugi S; Ricketts W; Olefsky JM
    Mol Endocrinol; 2005 Feb; 19(2):421-30. PubMed ID: 15486046
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.
    Skolnik EY; Lee CH; Batzer A; Vicentini LM; Zhou M; Daly R; Myers MJ; Backer JM; Ullrich A; White MF
    EMBO J; 1993 May; 12(5):1929-36. PubMed ID: 8491186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin.
    Pruett W; Yuan Y; Rose E; Batzer AG; Harada N; Skolnik EY
    Mol Cell Biol; 1995 Mar; 15(3):1778-85. PubMed ID: 7862167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway.
    Tauchi T; Boswell HS; Leibowitz D; Broxmeyer HE
    J Exp Med; 1994 Jan; 179(1):167-75. PubMed ID: 7505797
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recombinant human alpha 2-HS glycoprotein inhibits insulin-stimulated mitogenic pathway without affecting metabolic signalling in Chinese hamster ovary cells overexpressing the human insulin receptor.
    Srinivas PR; Deutsch DD; Mathews ST; Goustin AS; Leon MA; Grunberger G
    Cell Signal; 1996 Dec; 8(8):567-73. PubMed ID: 9115849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple hemopoietins, with the exception of interleukin-4, induce modification of Shc and mSos1, but not their translocation.
    Welham MJ; Duronio V; Leslie KB; Bowtell D; Schrader JW
    J Biol Chem; 1994 Aug; 269(33):21165-76. PubMed ID: 8063737
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways.
    Sasaoka T; Ishiki M; Sawa T; Ishihara H; Takata Y; Imamura T; Usui I; Olefsky JM; Kobayashi M
    Endocrinology; 1996 Oct; 137(10):4427-34. PubMed ID: 8828504
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The signaling pathway coupling epidermal growth factor receptors to activation of p21ras.
    Sasaoka T; Langlois WJ; Leitner JW; Draznin B; Olefsky JM
    J Biol Chem; 1994 Dec; 269(51):32621-5. PubMed ID: 7798267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins.
    Smit L; de Vries-Smits AM; Bos JL; Borst J
    J Biol Chem; 1994 Aug; 269(32):20209-12. PubMed ID: 8051109
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation.
    Waters SB; Chen D; Kao AW; Okada S; Holt KH; Pessin JE
    J Biol Chem; 1996 Jul; 271(30):18224-30. PubMed ID: 8663461
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relation between the insulin receptor number in cells, autophosphorylation and insulin-stimulated Ras.GTP formation.
    Osterop AP; Medema RH; Bos JL; vd Zon GC; Moller DE; Flier JS; Möller W; Maassen JA
    J Biol Chem; 1992 Jul; 267(21):14647-53. PubMed ID: 1634512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arachidonic acid mediates angiotensin II effects on p21ras in renal proximal tubular cells via the tyrosine kinase-Shc-Grb2-Sos pathway.
    Jiao H; Cui XL; Torti M; Chang CH; Alexander LD; Lapetina EG; Douglas JG
    Proc Natl Acad Sci U S A; 1998 Jun; 95(13):7417-21. PubMed ID: 9636164
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High affinity IgG receptor activation of Src family kinases is required for modulation of the Shc-Grb2-Sos complex and the downstream activation of the nicotinamide adenine dinucleotide phosphate (reduced) oxidase.
    Park RK; Erdreich-Epstein A; Liu M; Izadi KD; Durden DL
    J Immunol; 1999 Dec; 163(11):6023-34. PubMed ID: 10570290
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.
    VanderKuur J; Allevato G; Billestrup N; Norstedt G; Carter-Su C
    J Biol Chem; 1995 Mar; 270(13):7587-93. PubMed ID: 7535773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling.
    Kim B; Cheng HL; Margolis B; Feldman EL
    J Biol Chem; 1998 Dec; 273(51):34543-50. PubMed ID: 9852124
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
    Noguchi T; Matozaki T; Horita K; Fujioka Y; Kasuga M
    Mol Cell Biol; 1994 Oct; 14(10):6674-82. PubMed ID: 7935386
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.