These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
198 related articles for article (PubMed ID: 7819221)
1. Mutational analysis of the catalytic residues lysine 230 and tyrosine 160 in the NADP(+)-dependent isocitrate dehydrogenase from Escherichia coli. Lee ME; Dyer DH; Klein OD; Bolduc JM; Stoddard BL; Koshland DE Biochemistry; 1995 Jan; 34(1):378-84. PubMed ID: 7819221 [TBL] [Abstract][Full Text] [Related]
2. Active site water molecules revealed in the 2.1 A resolution structure of a site-directed mutant of isocitrate dehydrogenase. Cherbavaz DB; Lee ME; Stroud RM; Koshland DE J Mol Biol; 2000 Jan; 295(3):377-85. PubMed ID: 10623532 [TBL] [Abstract][Full Text] [Related]
3. Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP. Doyle SA; Beernink PT; Koshland DE Biochemistry; 2001 Apr; 40(14):4234-41. PubMed ID: 11284679 [TBL] [Abstract][Full Text] [Related]
4. Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase. Lee P; Colman RF Arch Biochem Biophys; 2002 May; 401(1):81-90. PubMed ID: 12054490 [TBL] [Abstract][Full Text] [Related]
5. Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase. Chen R; Grobler JA; Hurley JH; Dean AM Protein Sci; 1996 Feb; 5(2):287-95. PubMed ID: 8745407 [TBL] [Abstract][Full Text] [Related]
6. Evaluation by mutagenesis of the roles of His309, His315, and His319 in the coenzyme site of pig heart NADP-dependent isocitrate dehydrogenase. Huang YC; Colman RF Biochemistry; 2002 Apr; 41(17):5637-43. PubMed ID: 11969425 [TBL] [Abstract][Full Text] [Related]
7. Evaluation by site-directed mutagenesis of aspartic acid residues in the metal site of pig heart NADP-dependent isocitrate dehydrogenase. Grodsky NB; Soundar S; Colman RF Biochemistry; 2000 Mar; 39(9):2193-200. PubMed ID: 10694384 [TBL] [Abstract][Full Text] [Related]
8. Identification by mutagenesis of arginines in the substrate binding site of the porcine NADP-dependent isocitrate dehydrogenase. Soundar S; Danek BL; Colman RF J Biol Chem; 2000 Feb; 275(8):5606-12. PubMed ID: 10681542 [TBL] [Abstract][Full Text] [Related]
10. Synthesis, kinetics, and structural studies of a photolabile caged isocitrate: a catalytic trigger for isocitrate dehydrogenase. Brubaker MJ; Dyer DH; Stoddard B; Koshland DE Biochemistry; 1996 Mar; 35(9):2854-64. PubMed ID: 8608121 [TBL] [Abstract][Full Text] [Related]
11. Crystal structure of porcine mitochondrial NADP+-dependent isocitrate dehydrogenase complexed with Mn2+ and isocitrate. Insights into the enzyme mechanism. Ceccarelli C; Grodsky NB; Ariyaratne N; Colman RF; Bahnson BJ J Biol Chem; 2002 Nov; 277(45):43454-62. PubMed ID: 12207025 [TBL] [Abstract][Full Text] [Related]
12. Determinants of performance in the isocitrate dehydrogenase of Escherichia coli. Dean AM; Shiau AK; Koshland DE Protein Sci; 1996 Feb; 5(2):341-7. PubMed ID: 8745412 [TBL] [Abstract][Full Text] [Related]
13. Location of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase. Huang YC; Colman RF J Biol Chem; 2005 Aug; 280(34):30349-53. PubMed ID: 15975917 [TBL] [Abstract][Full Text] [Related]
14. Thr373, Asp375, and Lys260 are in the coenzyme site of porcine NADP-dependent isocitrate dehydrogenase. Lee P; Colman RF Arch Biochem Biophys; 2006 Jun; 450(2):183-90. PubMed ID: 16712772 [TBL] [Abstract][Full Text] [Related]
15. Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability. Karlström M; Stokke R; Steen IH; Birkeland NK; Ladenstein R J Mol Biol; 2005 Jan; 345(3):559-77. PubMed ID: 15581899 [TBL] [Abstract][Full Text] [Related]
16. Structure of a highly NADP+-specific isocitrate dehydrogenase. Sidhu NS; Delbaere LT; Sheldrick GM Acta Crystallogr D Biol Crystallogr; 2011 Oct; 67(Pt 10):856-69. PubMed ID: 21931217 [TBL] [Abstract][Full Text] [Related]
17. Active site mutants of Escherichia coli dethiobiotin synthetase: effects of mutations on enzyme catalytic and structural properties. Yang G; Sandalova T; Lohman K; Lindqvist Y; Rendina AR Biochemistry; 1997 Apr; 36(16):4751-60. PubMed ID: 9125495 [TBL] [Abstract][Full Text] [Related]
18. Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction. Peng Y; Zhong C; Huang W; Ding J Protein Sci; 2008 Sep; 17(9):1542-54. PubMed ID: 18552125 [TBL] [Abstract][Full Text] [Related]
19. Evolution of a transition state: role of Lys100 in the active site of isocitrate dehydrogenase. Miller SP; Gonçalves S; Matias PM; Dean AM Chembiochem; 2014 May; 15(8):1145-53. PubMed ID: 24797066 [TBL] [Abstract][Full Text] [Related]
20. Ser95, Asn97, and Thr78 are important for the catalytic function of porcine NADP-dependent isocitrate dehydrogenase. Kim TK; Colman RF Protein Sci; 2005 Jan; 14(1):140-7. PubMed ID: 15576556 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]