BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 7821752)

  • 1. Identification of specificity-determining residues in antibodies.
    Padlan EA; Abergel C; Tipper JP
    FASEB J; 1995 Jan; 9(1):133-9. PubMed ID: 7821752
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
    Li Y; Li H; Smith-Gill SJ; Mariuzza RA
    Biochemistry; 2000 May; 39(21):6296-309. PubMed ID: 10828942
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural significance of sequence variability in antibody complementarity-determining regions.
    Abergel C; Tipper JP; Padlan EA
    Res Immunol; 1994 Jan; 145(1):49-53. PubMed ID: 8008969
    [No Abstract]   [Full Text] [Related]  

  • 4. Systematic exploration of the antigen binding activity of synthetic peptides isolated from the variable regions of immunoglobulins.
    Laune D; Molina F; Ferrieres G; Mani JC; Cohen P; Simon D; Bernardi T; Piechaczyk M; Pau B; Granier C
    J Biol Chem; 1997 Dec; 272(49):30937-44. PubMed ID: 9388240
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antibody framework residues affecting the conformation of the hypervariable loops.
    Foote J; Winter G
    J Mol Biol; 1992 Mar; 224(2):487-99. PubMed ID: 1560463
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mutational analysis of the binding of two different proteins to the same antibody.
    Dall'Acqua W; Goldman ER; Eisenstein E; Mariuzza RA
    Biochemistry; 1996 Jul; 35(30):9667-76. PubMed ID: 8703938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular modeling of antibody-combining sites.
    Webster DM; Rees AR
    Methods Mol Biol; 1995; 51():17-49. PubMed ID: 7581695
    [No Abstract]   [Full Text] [Related]  

  • 8. Comparison of surface accessible residues in human and murine immunoglobulin Fv domains. Implication for humanization of murine antibodies.
    Pedersen JT; Henry AH; Searle SJ; Guild BC; Roguska M; Rees AR
    J Mol Biol; 1994 Jan; 235(3):959-73. PubMed ID: 7507176
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of an anti-digoxin antibody binding site by site-directed in vitro mutagenesis.
    Near RI; Mudgett-Hunter M; Novotny J; Bruccoleri R; Ng SC
    Mol Immunol; 1993 Mar; 30(4):369-77. PubMed ID: 8455637
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Three-dimensional structure of an antigen-antibody complex at 2.8 A resolution.
    Amit AG; Mariuzza RA; Phillips SE; Poljak RJ
    Science; 1986 Aug; 233(4765):747-53. PubMed ID: 2426778
    [TBL] [Abstract][Full Text] [Related]  

  • 11. "Superhumanized" antibodies: reduction of immunogenic potential by complementarity-determining region grafting with human germline sequences: application to an anti-CD28.
    Tan P; Mitchell DA; Buss TN; Holmes MA; Anasetti C; Foote J
    J Immunol; 2002 Jul; 169(2):1119-25. PubMed ID: 12097421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Energy-based analysis and prediction of the orientation between light- and heavy-chain antibody variable domains.
    Narayanan A; Sellers BD; Jacobson MP
    J Mol Biol; 2009 May; 388(5):941-53. PubMed ID: 19324053
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The His-probe method: effects of histidine residues introduced into the complementarity-determining regions of antibodies on antigen-antibody interactions at different pH values.
    Ito W; Sakato N; Fujio H; Yutani K; Arata Y; Kurosawa Y
    FEBS Lett; 1992 Aug; 309(1):85-8. PubMed ID: 1511750
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bovine IgM antibodies with exceptionally long complementarity-determining region 3 of the heavy chain share unique structural properties conferring restricted VH + Vlambda pairings.
    Saini SS; Farrugia W; Ramsland PA; Kaushik AK
    Int Immunol; 2003 Jul; 15(7):845-53. PubMed ID: 12807823
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The predicted structure of immunoglobulin D1.3 and its comparison with the crystal structure.
    Chothia C; Lesk AM; Levitt M; Amit AG; Mariuzza RA; Phillips SE; Poljak RJ
    Science; 1986 Aug; 233(4765):755-8. PubMed ID: 3090684
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Systematic classification of CDR-L3 in antibodies: implications of the light chain subtypes and the VL-VH interface.
    Kuroda D; Shirai H; Kobori M; Nakamura H
    Proteins; 2009 Apr; 75(1):139-46. PubMed ID: 18798566
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Grafting of "abbreviated" complementarity-determining regions containing specificity-determining residues essential for ligand contact to engineer a less immunogenic humanized monoclonal antibody.
    De Pascalis R; Iwahashi M; Tamura M; Padlan EA; Gonzales NR; Santos AD; Giuliano M; Schuck P; Schlom J; Kashmiri SV
    J Immunol; 2002 Sep; 169(6):3076-84. PubMed ID: 12218124
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Automated identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes.
    Ofran Y; Schlessinger A; Rost B
    J Immunol; 2008 Nov; 181(9):6230-5. PubMed ID: 18941213
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.
    Guddat LW; Shan L; Broomell C; Ramsland PA; Fan Z; Anchin JM; Linthicum DS; Edmundson AB
    J Mol Biol; 2000 Sep; 302(4):853-72. PubMed ID: 10993728
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites.
    Kabat EA; Wu TT
    J Immunol; 1991 Sep; 147(5):1709-19. PubMed ID: 1908882
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.