BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 7834794)

  • 1. Microsomal and peroxidase activation of 4-hydroxy-tamoxifen to form DNA adducts: comparison with DNA adducts formed in Sprague-Dawley rats treated with tamoxifen.
    Pathak DN; Pongracz K; Bodell WJ
    Carcinogenesis; 1995 Jan; 16(1):11-5. PubMed ID: 7834794
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA adduct formation by tamoxifen with rat and human liver microsomal activation systems.
    Pathak DN; Bodell WJ
    Carcinogenesis; 1994 Mar; 15(3):529-32. PubMed ID: 8118938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of the tamoxifen derivative metabolite E to form DNA adducts: comparison with the adducts formed by microsomal activation of tamoxifen.
    Pongracz K; Pathak DN; Nakamura T; Burlingame AL; Bodell WJ
    Cancer Res; 1995 Jul; 55(14):3012-5. PubMed ID: 7606720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen.
    Pathak DN; Pongracz K; Bodell WJ
    Carcinogenesis; 1996 Sep; 17(9):1785-90. PubMed ID: 8824496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.
    Randerath K; Moorthy B; Mabon N; Sriram P
    Carcinogenesis; 1994 Oct; 15(10):2087-94. PubMed ID: 7955037
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Production of 8-hydroxy-2'-deoxguanosine in DNA by microsomal activation of tamoxifen and 4-hydroxytamoxifen.
    Ye Q; Bodell WJ
    Carcinogenesis; 1996 Aug; 17(8):1747-50. PubMed ID: 8761436
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Formation of DNA adducts by microsomal and peroxidase activation of p-cresol: role of quinone methide in DNA adduct formation.
    Gaikwad NW; Bodell WJ
    Chem Biol Interact; 2001 Dec; 138(3):217-29. PubMed ID: 11714480
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tamoxifen metabolic activation: comparison of DNA adducts formed by microsomal and chemical activation of tamoxifen and 4-hydroxytamoxifen with DNA adducts formed in vivo.
    Moorthy B; Sriram P; Pathak DN; Bodell WJ; Randerath K
    Cancer Res; 1996 Jan; 56(1):53-7. PubMed ID: 8548775
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tamoxifen-DNA adduct formation in rat liver determined by immunoassay and 32P-postlabeling.
    Divi RL; Osborne MR; Hewer A; Phillips DH; Poirier MC
    Cancer Res; 1999 Oct; 59(19):4829-33. PubMed ID: 10519392
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA adducts caused by tamoxifen and toremifene in human microsomal system and lymphocytes in vitro.
    Hemminki K; Widlak P; Hou SM
    Carcinogenesis; 1995 Jul; 16(7):1661-4. PubMed ID: 7614704
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Immunohistochemical localization and semi-quantitation of hepatic tamoxifen-DNA adducts in rats exposed orally to tamoxifen.
    Divi RL; Dragan YP; Pitot HC; Poirier MC
    Carcinogenesis; 2001 Oct; 22(10):1693-9. PubMed ID: 11577011
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peroxidase-mediated dealkylation of tamoxifen, detected by electrospray ionization-mass spectrometry, and activation to form DNA adducts.
    Gaikwad NW; Bodell WJ
    Free Radic Biol Med; 2012 Jan; 52(2):340-7. PubMed ID: 22064363
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 32P-postlabeling analysis of benzo[a]pyrene-DNA adducts formed in vitro and in vivo.
    Bodell WJ; Devanesan PD; Rogan EG; Cavalieri EL
    Chem Res Toxicol; 1989; 2(5):312-5. PubMed ID: 2519823
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats.
    Phillips DH; Hewer A; White IN; Farmer PB
    Carcinogenesis; 1994 May; 15(5):793-5. PubMed ID: 8200077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence that the catechol 3,4-Dihydroxytamoxifen is a proximate intermediate to the reactive species binding covalently to proteins.
    Dehal SS; Kupfer D
    Cancer Res; 1996 Mar; 56(6):1283-90. PubMed ID: 8640815
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formation of tamoxifen-DNA adducts via O-sulfonation, not O-acetylation, of alpha-hydroxytamoxifen in rat and human livers.
    Kim SY; Laxmi YR; Suzuki N; Ogura K; Watabe T; Duffel MW; Shibutani S
    Drug Metab Dispos; 2005 Nov; 33(11):1673-8. PubMed ID: 16099924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Examination of microsomal cytochrome P450-catalyzed in vitro activation of o-phenylphenol to DNA binding metabolite(s) by 32P-postlabeling technique.
    Pathak DN; Roy D
    Carcinogenesis; 1992 Sep; 13(9):1593-7. PubMed ID: 1394845
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 32P-postlabeling analysis of adducts generated by peroxidase-mediated binding of N-hydroxy-4-acetylaminobiphenyl to DNA.
    Hatcher JF; Swaminathan S
    Carcinogenesis; 1995 Sep; 16(9):2149-57. PubMed ID: 7554068
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxidation of eugenol to form DNA adducts and 8-hydroxy-2'-deoxyguanosine: role of quinone methide derivative in DNA adduct formation.
    Bodell WJ; Ye Q; Pathak DN; Pongracz K
    Carcinogenesis; 1998 Mar; 19(3):437-43. PubMed ID: 9525278
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Formation of tamoxifen-DNA adducts in multiple organs of adult female cynomolgus monkeys dosed with tamoxifen for 30 days.
    Schild LJ; Divi RL; Beland FA; Churchwell MI; Doerge DR; Gamboa da Costa G; Marques MM; Poirier MC
    Cancer Res; 2003 Sep; 63(18):5999-6003. PubMed ID: 14522927
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.