103 related articles for article (PubMed ID: 7837221)
1. Pyrrolo[1,2-a]benzimidazole-based quinones and iminoquinones. The role of the 3-substituent on cytotoxicity.
Schulz WG; Islam I; Skibo EB
J Med Chem; 1995 Jan; 38(1):109-18. PubMed ID: 7837221
[TBL] [Abstract][Full Text] [Related]
2. Studies of pyrrolo[1,2-alpha]benzimidazolequinone DT-diaphorase substrate activity, topoisomerase II inhibition activity, and DNA reductive alkylation.
Skibo EB; Gordon S; Bess L; Boruah R; Heileman MJ
J Med Chem; 1997 Apr; 40(9):1327-39. PubMed ID: 9135030
[TBL] [Abstract][Full Text] [Related]
3. Chemistry of the pyrrolo[1,2-alpha]benzimidazole antitumor agents: influence of the 7-substituent on the ability to alkylate DNA and inhibit topoisomerase II.
Zhou R; Skibo EB
J Med Chem; 1996 Oct; 39(21):4321-31. PubMed ID: 8863809
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of topoisomerase II based on the benzodiimidazole and dipyrroloimidazobenzimidazole ring systems: controlling DT-diaphorase reductive inactivation with steric bulk.
Schulz WG; Skibo EB
J Med Chem; 2000 Feb; 43(4):629-38. PubMed ID: 10691689
[TBL] [Abstract][Full Text] [Related]
5. Structure-activity studies of benzimidazole-based DNA-cleaving agents. Comparison of benzimidazole, pyrrolobenzimidazole, and tetrahydropyridobenzimidazole analogues.
Skibo EB; Islam I; Heileman MJ; Schulz WG
J Med Chem; 1994 Jan; 37(1):78-92. PubMed ID: 8289204
[TBL] [Abstract][Full Text] [Related]
6. Design of highly active analogues of the pyrrolo[1,2-a]benzimidazole antitumor agents.
Craigo WA; LeSueur BW; Skibo EB
J Med Chem; 1999 Aug; 42(17):3324-33. PubMed ID: 10464019
[TBL] [Abstract][Full Text] [Related]
7. Pyrrolo[1,2-a]benzimidazole-based aziridinyl quinones. A new class of DNA cleaving agent exhibiting G and A base specificity.
Skibo EB; Schulz WG
J Med Chem; 1993 Oct; 36(21):3050-5. PubMed ID: 8230090
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and antiproliferative activity of decarbonyl luotonin analogues.
Almansour AI; Arumugam N; Suresh Kumar R; Mahalingam SM; Sau S; Bianchini G; Menéndez JC; Altaf M; Ghabbour HA
Eur J Med Chem; 2017 Sep; 138():932-941. PubMed ID: 28753517
[TBL] [Abstract][Full Text] [Related]
9. A comparison of the cytotoxic and physical properties of aziridinyl quinone derivatives based on the pyrrolo[1,2-a]benzimidazole and pyrrolo[1,2-a]indole ring systems.
Boruah RC; Skibo EB
J Med Chem; 1994 May; 37(11):1625-31. PubMed ID: 8201596
[TBL] [Abstract][Full Text] [Related]
10. COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.
Fagan V; Bonham S; Carty MP; Saenz-Méndez P; Eriksson LA; Aldabbagh F
Bioorg Med Chem; 2012 May; 20(10):3223-32. PubMed ID: 22522008
[TBL] [Abstract][Full Text] [Related]
11. Pyrrolobenzimidazoles linked to heterocycles and peptides. Design of DNA base pair specific phosphate hydrolyzing agents and novel cytotoxic agents.
Ghodousi A; Huang X; Cheng Z; Skibo EB
J Med Chem; 2004 Jan; 47(1):90-100. PubMed ID: 14695823
[TBL] [Abstract][Full Text] [Related]
12. Studies on quinones. Part 45: novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines.
Valderrama JA; Ibacache JA; Arancibia V; Rodriguez J; Theoduloz C
Bioorg Med Chem; 2009 Apr; 17(7):2894-901. PubMed ID: 19269832
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and antitumor evaluation of 8-phenylaminopyrimido[4,5-c]isoquinolinequinones.
Vásquez D; Rodríguez JA; Theoduloz C; Verrax J; Calderon PB; Valderrama JA
Bioorg Med Chem Lett; 2009 Sep; 19(17):5060-2. PubMed ID: 19631536
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and in vitro cytotoxic evaluation of some thiazolylbenzimidazole derivatives.
Luo Y; Xiao F; Qian S; Lu W; Yang B
Eur J Med Chem; 2011 Jan; 46(1):417-22. PubMed ID: 21115212
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity.
Kamal A; Ramulu P; Srinivas O; Ramesh G; Kumar PP
Bioorg Med Chem Lett; 2004 Sep; 14(18):4791-4. PubMed ID: 15324909
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and antitumor cytotoxicity of novel bis-benzimidazoles.
Singh AK; Lown JW
Anticancer Drug Des; 2000 Aug; 15(4):265-75. PubMed ID: 11200502
[TBL] [Abstract][Full Text] [Related]
17. Benzimidazole condensed ring systems. XII. Synthesis and anticancer evaluation of certain pyrido[1,2-a]benzimidazole derivatives.
el-Hawash SA; Badawey el-S A; Kappe T
Pharmazie; 1999 May; 54(5):341-6. PubMed ID: 10368827
[TBL] [Abstract][Full Text] [Related]
18. Heterocyclic quinones with potential antitumor activity. 2. Synthesis and antitumor activity of some benzimidazole-4,7-dione derivatives.
Antonini I; Claudi F; Cristalli G; Franchetti P; Grifantini M; Martelli S
J Med Chem; 1988 Jan; 31(1):260-4. PubMed ID: 3336025
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of 6-aziridinylbenzimidazole derivatives and their in vitro antitumor activities.
Ahn CM; Kim SK; Han JL
Arch Pharm Res; 1998 Oct; 21(5):599-609. PubMed ID: 9875502
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of new benzimidazole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates with efficient DNA-binding affinity and potent cytotoxicity.
Kamal A; Kumar PP; Sreekanth K; Seshadri BN; Ramulu P
Bioorg Med Chem Lett; 2008 Apr; 18(8):2594-8. PubMed ID: 18378445
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
