BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 7841337)

  • 1. Formation of NADP(H) analogs of tobacco-specific nitrosamines in rat liver and pancreatic microsomes.
    Peterson LA; Ng DK; Stearns RA; Hecht SS
    Chem Res Toxicol; 1994; 7(5):599-608. PubMed ID: 7841337
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
    Collazo NR; Sultatos LG
    Biochem Pharmacol; 1995 Nov; 50(11):1933-41. PubMed ID: 8615875
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P; Kalscheuer S; Hochalter JB; Villalta PW; Hecht SS
    Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
    Staretz ME; Murphy SE; Patten CJ; Nunes MG; Koehl W; Amin S; Koenig LA; Guengerich FP; Hecht SS
    Drug Metab Dispos; 1997 Feb; 25(2):154-62. PubMed ID: 9029045
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P; Kenney PM; Hochalter JB; Wang M; Hecht SS
    Carcinogenesis; 1999 Aug; 20(8):1577-82. PubMed ID: 10426810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols.
    Trushin N; Leder G; El-Bayoumy K; Hoffmann D; Beger HG; Henne-Bruns D; Ramadani M; Prokopczyk B
    Langenbecks Arch Surg; 2008 Jul; 393(4):571-9. PubMed ID: 18259773
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K; Trushin N; Hecht SS; Stoner GD
    Carcinogenesis; 1991 Jun; 12(6):1029-34. PubMed ID: 2044181
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Formation and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers in vitro in mouse, rat and human tissues.
    Upadhyaya P; Carmella SG; Guengerich FP; Hecht SS
    Carcinogenesis; 2000 Jun; 21(6):1233-8. PubMed ID: 10837015
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Staretz ME; Koenig LA; Hecht SS
    Carcinogenesis; 1997 Sep; 18(9):1715-22. PubMed ID: 9328166
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.
    Belinsky SA; White CM; Trushin N; Hecht SS
    Carcinogenesis; 1989 Dec; 10(12):2269-74. PubMed ID: 2591016
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intestinal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats: Sex difference, inducibility and inhibition by phenethylisothiocyanate.
    Schulze J; Malone A; Richter E
    Carcinogenesis; 1995 Aug; 16(8):1733-40. PubMed ID: 7634397
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
    Prokopczyk B; Trushin N; Leszczynska J; Waggoner SE; El-Bayoumy K
    Carcinogenesis; 2001 Jan; 22(1):107-14. PubMed ID: 11159748
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung.
    Atalla A; Maser E
    Toxicology; 1999 Nov; 139(1-2):155-66. PubMed ID: 10614696
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of a glucuronide metabolite of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its dose-dependent excretion in the urine of mice and rats.
    Morse MA; Eklind KI; Toussaint M; Amin SG; Chung FL
    Carcinogenesis; 1990 Oct; 11(10):1819-23. PubMed ID: 2208595
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
    Guo Z; Smith TJ; Thomas PE; Yang CS
    Arch Biochem Biophys; 1992 Oct; 298(1):279-86. PubMed ID: 1524438
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Ma B; Zarth AT; Carlson ES; Villalta PW; Upadhyaya P; Stepanov I; Hecht SS
    Chem Res Toxicol; 2018 Jan; 31(1):48-57. PubMed ID: 29131934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA and hemoglobin alkylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Hecht SS; Trushin N
    Carcinogenesis; 1988 Sep; 9(9):1665-8. PubMed ID: 3409470
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Schrader E; Hirsch-Ernst KI; Richter E; Foth H
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar; 357(3):336-43. PubMed ID: 9550307
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of a glucuronide conjugate of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats.
    Atawodi SE; Michelsen K; Richter E
    Arch Toxicol; 1994; 69(1):14-7. PubMed ID: 7717849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG; Borukhova A; Akerkar SA; Hecht SS
    Cancer Epidemiol Biomarkers Prev; 1997 Feb; 6(2):113-20. PubMed ID: 9037562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.