111 related articles for article (PubMed ID: 7843134)
1. Induction of lung-specific DNA damage by metabolically methylated arsenics via the production of free radicals.
Yamanaka K; Okada S
Environ Health Perspect; 1994 Sep; 102 Suppl 3(Suppl 3):37-40. PubMed ID: 7843134
[TBL] [Abstract][Full Text] [Related]
2. Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenics, is for the major part likely due to its peroxyl radical.
Yamanaka K; Hoshino M; Okamoto M; Sawamura R; Hasegawa A; Okada S
Biochem Biophys Res Commun; 1990 Apr; 168(1):58-64. PubMed ID: 2158319
[TBL] [Abstract][Full Text] [Related]
3. DNA-strand breaks induced by dimethylarsinic acid, a metabolite of inorganic arsenics, are strongly enhanced by superoxide anion radicals.
Rin K; Kawaguchi K; Yamanaka K; Tezuka M; Oku N; Okada S
Biol Pharm Bull; 1995 Jan; 18(1):45-8. PubMed ID: 7735248
[TBL] [Abstract][Full Text] [Related]
4. Dimethylated arsenics induce DNA strand breaks in lung via the production of active oxygen in mice.
Yamanaka K; Hasegawa A; Sawamura R; Okada S
Biochem Biophys Res Commun; 1989 Nov; 165(1):43-50. PubMed ID: 2590239
[TBL] [Abstract][Full Text] [Related]
5. Cellular response to oxidative damage in lung induced by the administration of dimethylarsinic acid, a major metabolite of inorganic arsenics, in mice.
Yamanaka K; Hasegawa A; Sawamura R; Okada S
Toxicol Appl Pharmacol; 1991 Apr; 108(2):205-13. PubMed ID: 2017750
[TBL] [Abstract][Full Text] [Related]
6. Crosslink formation between DNA and nuclear proteins by in vivo and in vitro exposure of cells to dimethylarsinic acid.
Yamanaka K; Tezuka M; Kato K; Hasegawa A; Okada S
Biochem Biophys Res Commun; 1993 Mar; 191(3):1184-91. PubMed ID: 8466494
[TBL] [Abstract][Full Text] [Related]
7. DNA strand breaks in mammalian tissues induced by methylarsenics.
Yamanaka K; Hasegawa A; Sawamura R; Okada S
Biol Trace Elem Res; 1989; 21():413-7. PubMed ID: 2484622
[TBL] [Abstract][Full Text] [Related]
8. Involvement of preferential formation of apurinic/apyrimidinic sites in dimethylarsenic-induced DNA strand breaks and DNA-protein crosslinks in cultured alveolar epithelial cells.
Yamanaka K; Hayashi H; Kato K; Hasegawa A; Okada S
Biochem Biophys Res Commun; 1995 Feb; 207(1):244-9. PubMed ID: 7857272
[TBL] [Abstract][Full Text] [Related]
9. The role of active arsenic species produced by metabolic reduction of dimethylarsinic acid in genotoxicity and tumorigenesis.
Yamanaka K; Kato K; Mizoi M; An Y; Takabayashi F; Nakano M; Hoshino M; Okada S
Toxicol Appl Pharmacol; 2004 Aug; 198(3):385-93. PubMed ID: 15276418
[TBL] [Abstract][Full Text] [Related]
10. Metabolic methylation is a possible genotoxicity-enhancing process of inorganic arsenics.
Yamanaka K; Hayashi H; Tachikawa M; Kato K; Hasegawa A; Oku N; Okada S
Mutat Res; 1997 Nov; 394(1-3):95-101. PubMed ID: 9434848
[TBL] [Abstract][Full Text] [Related]
11. Gene damage induced in human alveolar type II (L-132) cells by exposure to dimethylarsinic acid.
Tezuka M; Hanioka K; Yamanaka K; Okada S
Biochem Biophys Res Commun; 1993 Mar; 191(3):1178-83. PubMed ID: 7682063
[TBL] [Abstract][Full Text] [Related]
12. Oral exposure of dimethylarsinic acid, a main metabolite of inorganic arsenics, in mice leads to an increase in 8-Oxo-2'-deoxyguanosine level, specifically in the target organs for arsenic carcinogenesis.
Yamanaka K; Takabayashi F; Mizoi M; An Y; Hasegawa A; Okada S
Biochem Biophys Res Commun; 2001 Sep; 287(1):66-70. PubMed ID: 11549254
[TBL] [Abstract][Full Text] [Related]
13. Mutagenicity of dimethylated metabolites of inorganic arsenics.
Yamanaka K; Ohba H; Hasegawa A; Sawamura R; Okada S
Chem Pharm Bull (Tokyo); 1989 Oct; 37(10):2753-6. PubMed ID: 2692857
[TBL] [Abstract][Full Text] [Related]
14. DNA damage induced in cultured human alveolar (L-132) cells by exposure to dimethylarsinic acid.
Kato K; Hayashi H; Hasegawa A; Yamanaka K; Okada S
Environ Health Perspect; 1994 Sep; 102 Suppl 3(Suppl 3):285-8. PubMed ID: 7843116
[TBL] [Abstract][Full Text] [Related]
15. Metallothionein (I/II) suppresses genotoxicity caused by dimethylarsinic acid.
Jia G; Sone H; Nishimura N; Satoh M; Tohyama C
Int J Oncol; 2004 Aug; 25(2):325-33. PubMed ID: 15254729
[TBL] [Abstract][Full Text] [Related]
16. Role of Cu/Zn-superoxide dismutase in xenobiotic activation. II. Biological effects resulting from the Cu/Zn-superoxide dismutase-accelerated oxidation of the benzene metabolite 1,4-hydroquinone.
Li Y; Kuppusamy P; Zweir JL; Trush MA
Mol Pharmacol; 1996 Mar; 49(3):412-21. PubMed ID: 8643080
[TBL] [Abstract][Full Text] [Related]
17. Preferential increase of heterochromatin in venular endothelium of lung in mice after administration of dimethylarsinic acid, a major metabolite of inorganic arsenics.
Nakano M; Yamanaka K; Hasegawa A; Sawamura R; Okada S
Carcinogenesis; 1992 Mar; 13(3):391-3. PubMed ID: 1547528
[TBL] [Abstract][Full Text] [Related]
18. Dimethylarsine likely acts as a mouse-pulmonary tumor initiator via the production of dimethylarsine radical and/or its peroxy radical.
Yamanaka K; Kato K; Mizoi M; An Y; Nakanao M; Hoshino M; Okada S
Life Sci; 2009 Apr; 84(17-18):627-33. PubMed ID: 26324994
[TBL] [Abstract][Full Text] [Related]
19. Dimethylarsinic acid, a main metabolite of inorganic arsenics, has tumorigenicity and progression effects in the pulmonary tumors of A/J mice.
Hayashi H; Kanisawa M; Yamanaka K; Ito T; Udaka N; Ohji H; Okudela K; Okada S; Kitamura H
Cancer Lett; 1998 Mar; 125(1-2):83-8. PubMed ID: 9566700
[TBL] [Abstract][Full Text] [Related]
20. Dimethylarsenics reveal DNA damage induced by superoxide anion radicals.
Kawaguchi K; Oku N; Rin K; Yamanaka K; Okada S
Biol Pharm Bull; 1996 Apr; 19(4):551-3. PubMed ID: 8860956
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
