162 related articles for article (PubMed ID: 7847874)
1. Anti-influenza virus activity of the neuraminidase inhibitor 4-guanidino-Neu5Ac2en in cell culture and in human respiratory epithelium.
Hayden FG; Rollins BS; Madren LK
Antiviral Res; 1994 Oct; 25(2):123-31. PubMed ID: 7847874
[TBL] [Abstract][Full Text] [Related]
2. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro.
Woods JM; Bethell RC; Coates JA; Healy N; Hiscox SA; Pearson BA; Ryan DM; Ticehurst J; Tilling J; Walcott SM
Antimicrob Agents Chemother; 1993 Jul; 37(7):1473-9. PubMed ID: 8363379
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor.
Sidwell RW; Huffman JH; Barnard DL; Bailey KW; Wong MH; Morrison A; Syndergaard T; Kim CU
Antiviral Res; 1998 Feb; 37(2):107-20. PubMed ID: 9588843
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of replication of avian influenza viruses by the neuraminidase inhibitor 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid.
Gubareva LV; Penn CR; Webster RG
Virology; 1995 Oct; 212(2):323-30. PubMed ID: 7571401
[TBL] [Abstract][Full Text] [Related]
5. Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en.
Staschke KA; Colacino JM; Baxter AJ; Air GM; Bansal A; Hornback WJ; Munroe JE; Laver WG
Virology; 1995 Dec; 214(2):642-6. PubMed ID: 8553569
[TBL] [Abstract][Full Text] [Related]
6. Neuraminidase inhibitor-rimantadine combinations exert additive and synergistic anti-influenza virus effects in MDCK cells.
Govorkova EA; Fang HB; Tan M; Webster RG
Antimicrob Agents Chemother; 2004 Dec; 48(12):4855-63. PubMed ID: 15561867
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and influenza virus sialidase inhibitory activity of analogues of 4-Guanidino-Neu5Ac2en (Zanamivir) modified in the glycerol side-chain.
Andrews DM; Cherry PC; Humber DC; Jones PS; Keeling SP; Martin PF; Shaw CD; Swanson S
Eur J Med Chem; 1999; 34(7-8):563-74. PubMed ID: 11278042
[TBL] [Abstract][Full Text] [Related]
8. Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.
Gubareva LV; Robinson MJ; Bethell RC; Webster RG
J Virol; 1997 May; 71(5):3385-90. PubMed ID: 9094607
[TBL] [Abstract][Full Text] [Related]
9. Zanamivir. A potent and selective inhibitor of influenza A and B viruses.
Aoki FY; Hayden FG
Clin Pharmacokinet; 1999; 36 Suppl 1():v-ix. PubMed ID: 10429834
[No Abstract] [Full Text] [Related]
10. Selection of influenza A and B viruses for resistance to 4-guanidino-Neu5Ac2en in cell culture.
Colacino JM; Laver WG; Air GM
J Infect Dis; 1997 Aug; 176 Suppl 1():S66-8. PubMed ID: 9240698
[TBL] [Abstract][Full Text] [Related]
11. Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en.
McKimm-Breschkin JL; Blick TJ; Sahasrabudhe A; Tiong T; Marshall D; Hart GJ; Bethell RC; Penn CR
Antimicrob Agents Chemother; 1996 Jan; 40(1):40-6. PubMed ID: 8787876
[TBL] [Abstract][Full Text] [Related]
12. Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities.
Smee DF; Huffman JH; Morrison AC; Barnard DL; Sidwell RW
Antimicrob Agents Chemother; 2001 Mar; 45(3):743-8. PubMed ID: 11181354
[TBL] [Abstract][Full Text] [Related]
13. Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection.
Mendel DB; Tai CY; Escarpe PA; Li W; Sidwell RW; Huffman JH; Sweet C; Jakeman KJ; Merson J; Lacy SA; Lew W; Williams MA; Zhang L; Chen MS; Bischofberger N; Kim CU
Antimicrob Agents Chemother; 1998 Mar; 42(3):640-6. PubMed ID: 9517945
[TBL] [Abstract][Full Text] [Related]
14. Efficacy of zanamivir against avian influenza A viruses that possess genes encoding H5N1 internal proteins and are pathogenic in mammals.
Leneva IA; Goloubeva O; Fenton RJ; Tisdale M; Webster RG
Antimicrob Agents Chemother; 2001 Apr; 45(4):1216-24. PubMed ID: 11257037
[TBL] [Abstract][Full Text] [Related]
15. Phenotypic drug susceptibility assay for influenza virus neuraminidase inhibitors.
McSharry JJ; McDonough AC; Olson BA; Drusano GL
Clin Diagn Lab Immunol; 2004 Jan; 11(1):21-8. PubMed ID: 14715540
[TBL] [Abstract][Full Text] [Related]
16. Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en.
Gubareva LV; Bethell R; Hart GJ; Murti KG; Penn CR; Webster RG
J Virol; 1996 Mar; 70(3):1818-27. PubMed ID: 8627706
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.
Masuda T; Yoshida S; Arai M; Kaneko S; Yamashita M; Honda T
Chem Pharm Bull (Tokyo); 2003 Dec; 51(12):1386-98. PubMed ID: 14646315
[TBL] [Abstract][Full Text] [Related]
18. Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en.
Blick TJ; Tiong T; Sahasrabudhe A; Varghese JN; Colman PM; Hart GJ; Bethell RC; McKimm-Breschkin JL
Virology; 1995 Dec; 214(2):475-84. PubMed ID: 8553549
[TBL] [Abstract][Full Text] [Related]
19. [Study of the antiviral activity of Russian anti-influenza agents in cell culture and animal models].
Leneva IA; Fediakina IT; Eropkin MIu; Gudova NV; Romanovskaia AA; Danilenko DM; Vinogradova SM; Lepeshkin AIu; Shestopalov AM
Vopr Virusol; 2010; 55(3):19-27. PubMed ID: 20608077
[TBL] [Abstract][Full Text] [Related]
20. Comparison of efficacies of RWJ-270201, zanamivir, and oseltamivir against H5N1, H9N2, and other avian influenza viruses.
Govorkova EA; Leneva IA; Goloubeva OG; Bush K; Webster RG
Antimicrob Agents Chemother; 2001 Oct; 45(10):2723-32. PubMed ID: 11557461
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
