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26. Mg(2+)-dependent conformational changes in the hammerhead ribozyme. Menger M; Tuschl T; Eckstein F; Porschke D Biochemistry; 1996 Nov; 35(47):14710-6. PubMed ID: 8942631 [TBL] [Abstract][Full Text] [Related]
27. A covalent crosslink converts the hammerhead ribozyme from a ribonuclease to an RNA ligase. Stage-Zimmermann TK; Uhlenbeck OC Nat Struct Biol; 2001 Oct; 8(10):863-7. PubMed ID: 11573091 [TBL] [Abstract][Full Text] [Related]
28. Mechanistic characterization of the HDV genomic ribozyme: assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism. Nakano S; Proctor DJ; Bevilacqua PC Biochemistry; 2001 Oct; 40(40):12022-38. PubMed ID: 11580278 [TBL] [Abstract][Full Text] [Related]
29. Substitution of the 2'-hydroxyl group at position 2.1 by an amino group interferes with Mg(2+) binding and efficient cleavage by hammerhead ribozyme. Sioud M; Leirdal M Biochem Biophys Res Commun; 1999 Aug; 262(2):461-6. PubMed ID: 10462497 [TBL] [Abstract][Full Text] [Related]
30. Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism. Dahm SC; Derrick WB; Uhlenbeck OC Biochemistry; 1993 Dec; 32(48):13040-5. PubMed ID: 8241158 [TBL] [Abstract][Full Text] [Related]
31. A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate. Simorre JP; Legault P; Hangar AB; Michiels P; Pardi A Biochemistry; 1997 Jan; 36(3):518-25. PubMed ID: 9012667 [TBL] [Abstract][Full Text] [Related]
32. Diffusely bound Mg2+ ions slightly reorient stems I and II of the hammerhead ribozyme to increase the probability of formation of the catalytic core. Rueda D; Wick K; McDowell SE; Walter NG Biochemistry; 2003 Aug; 42(33):9924-36. PubMed ID: 12924941 [TBL] [Abstract][Full Text] [Related]
33. Evidence for processivity and two-step binding of the RNA substrate from studies of J1/2 mutants of the Tetrahymena ribozyme. Herschlag D Biochemistry; 1992 Feb; 31(5):1386-99. PubMed ID: 1736996 [TBL] [Abstract][Full Text] [Related]
34. Importance of magnesium ions in the mechanism of catalysis by a hammerhead ribozyme: strictly linear relationship between the ribozyme activity and the concentration of magnesium ions. Inoue A; Takagi Y; Taira K Magnes Res; 2003 Sep; 16(3):210-7. PubMed ID: 14596326 [TBL] [Abstract][Full Text] [Related]
35. Temperature-dependent change in the rate-determining step in a reaction catalyzed by a hammerhead ribozyme. Takagi Y; Taira K FEBS Lett; 1995 Mar; 361(2-3):273-6. PubMed ID: 7698337 [TBL] [Abstract][Full Text] [Related]
36. In vitro optimization of truncated stem-loop II variants of the hammerhead ribozyme for cleavage in low concentrations of magnesium under non-turnover conditions. Zillmann M; Limauro SE; Goodchild J RNA; 1997 Jul; 3(7):734-47. PubMed ID: 9214657 [TBL] [Abstract][Full Text] [Related]
37. Low-magnesium, trans-cleavage activity by type III, tertiary stabilized hammerhead ribozymes with stem 1 discontinuities. Burke DH; Greathouse ST BMC Biochem; 2005 Aug; 6():14. PubMed ID: 16095542 [TBL] [Abstract][Full Text] [Related]
38. Structure of the ribozyme substrate hairpin of Neurospora VS RNA: a close look at the cleavage site. Michiels PJ; Schouten CH; Hilbers CW; Heus HA RNA; 2000 Dec; 6(12):1821-32. PubMed ID: 11142381 [TBL] [Abstract][Full Text] [Related]
39. Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding. Koizumi M; Ohtsuka E Biochemistry; 1991 May; 30(21):5145-50. PubMed ID: 2036380 [TBL] [Abstract][Full Text] [Related]