BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 7850919)

  • 1. Cytotoxic and biochemical implications of combining AZT and AG-331.
    Pressacco J; Mitrovski B; Erlichman C
    Cancer Chemother Pharmacol; 1995; 35(5):387-90. PubMed ID: 7850919
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biochemical modulation of iododeoxyuridine by N6-[4-(morpholinosulfonyl)benzyl]-N6-methyl-2,6-diaminobenz[cd]indole glucuronate (AG-331) leading to enhanced cytotoxicity.
    Pressacco J; Mitrovski B; Hedley DW; Tsang R; Erlichman C
    Biochem Pharmacol; 1995 Jun; 50(1):55-60. PubMed ID: 7605345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combination studies with 3'-azido-3'-deoxythymidine (AZT) plus ICI D1694. Cytotoxic and biochemical effects.
    Pressacco J; Erlichman C
    Biochem Pharmacol; 1993 Dec; 46(11):1989-97. PubMed ID: 8267649
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ICI D1694 and idoxuridine: a synergistic antitumor combination.
    Pressacco J; Hedley DW; Erlichman C
    Cancer Res; 1994 Jul; 54(14):3772-8. PubMed ID: 8033097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of thymidylate synthase inhibition on thymidine kinase activity and nucleoside transporter expression.
    Pressacco J; Mitrovski B; Erlichman C; Hedley DW
    Cancer Res; 1995 Apr; 55(7):1505-8. PubMed ID: 7882359
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8.
    Darnowski JW; Goulette FA
    Biochem Pharmacol; 1994 Nov; 48(9):1797-805. PubMed ID: 7980649
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Azidothymidine-induced cytotoxicity and incorporation into DNA in the human colon tumor cell line HCT-8 is enhanced by methotrexate in vitro and in vivo.
    Tosi P; Calabresi P; Goulette FA; Renaud CA; Darnowski JW
    Cancer Res; 1992 Aug; 52(15):4069-73. PubMed ID: 1638518
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil +/- leucovorin in MGH-U1 cells.
    Erlichman C; Mitrovski B
    Cancer Chemother Pharmacol; 1994; 34(1):51-6. PubMed ID: 8174202
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study.
    Jackman AL; Taylor GA; Gibson W; Kimbell R; Brown M; Calvert AH; Judson IR; Hughes LR
    Cancer Res; 1991 Oct; 51(20):5579-86. PubMed ID: 1913676
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-Fluorouracil enhances azidothymidine cytotoxicity: in vitro, in vivo, and biochemical studies.
    Brunetti I; Falcone A; Calabresi P; Goulette FA; Darnowski JW
    Cancer Res; 1990 Jul; 50(13):4026-31. PubMed ID: 2354452
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biochemical effects of folate-based inhibitors of thymidylate synthase in MGH-U1 cells.
    Mitrovski B; Pressacco J; Mandelbaum S; Erlichman C
    Cancer Chemother Pharmacol; 1994; 35(2):109-14. PubMed ID: 7987985
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biological activity of a novel rationally designed lipophilic thymidylate synthase inhibitor.
    O'Connor BM; Webber S; Jackson RC; Galivan J; Rhee MS
    Cancer Chemother Pharmacol; 1994; 34(3):225-9. PubMed ID: 8004755
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Time dependence of DNA lesions and growth inhibition by ICI D1694, a new quinazoline antifolate thymidylate synthase inhibitor.
    Yin MB; Guimaraes MA; Zhang ZG; Arredondo MA; Rustum YM
    Cancer Res; 1992 Nov; 52(21):5900-5. PubMed ID: 1394217
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effect of recombinant human granulocyte-macrophage colony-stimulating factor (rGM-CSF) on 3'-azido-3'-deoxythymidine (AZT)-mediated biochemical and cytotoxic effects on normal human myeloid progenitor cells.
    Bhalla K; Birkhofer M; Grant S; Graham G
    Exp Hematol; 1989 Jan; 17(1):17-20. PubMed ID: 2783247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine.
    Gao WY; Johns DG; Tanaka M; Mitsuya H
    Mol Pharmacol; 1999 Mar; 55(3):535-40. PubMed ID: 10051538
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Quantitative analysis of 3'-azido-3'-deoxythymidine incorporation into DNA in human colon tumor cells.
    Sharma M; Jain R; Ionescu E; Darnowski JW
    Bioconjug Chem; 1995; 6(5):536-40. PubMed ID: 8974451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro uptake, anabolism, and cellular retention of 1843U89 and other benzoquinazoline inhibitors of thymidylate synthase.
    Hanlon MH; Ferone R
    Cancer Res; 1996 Jul; 56(14):3301-6. PubMed ID: 8764125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of the cytotoxicity of 3'-azido-3'-deoxythymidine and methotrexate after transduction of folate receptor cDNA into human cervical carcinoma: identification of a correlation between folate receptor expression and thymidine kinase activity.
    Sun XL; Jayaram HN; Gharehbaghi K; Li QJ; Xiao X; Antony AC
    Cancer Res; 1999 Feb; 59(4):940-6. PubMed ID: 10029088
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human recombinant interferon alpha-2a plus 3'-azido-3'-deoxythymidine. Synergistic growth inhibition with evidence of impaired DNA repair in human colon adenocarcinoma cells.
    Darnowski JW; Davol PA; Goulette FA
    Biochem Pharmacol; 1997 Feb; 53(4):571-80. PubMed ID: 9105409
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.