BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 7852193)

  • 1. Differential effect of duocarmycin A and its novel derivative DU-86 on DNA strand breaks in HeLa S3 cells.
    Okamoto A; Asai A; Saito H; Okabe M; Gomi K
    Jpn J Cancer Res; 1994 Dec; 85(12):1304-11. PubMed ID: 7852193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of DNA fragmentation in human uterine cervix carcinoma HeLa S3 cells treated with duocarmycins or other antitumor agents by pulse field gel electrophoresis.
    Okamoto A; Okabe M; Gomi K
    Jpn J Cancer Res; 1993 Jan; 84(1):93-8. PubMed ID: 8449832
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anticellular and antitumor activity of duocarmycins, novel antitumor antibiotics.
    Gomi K; Kobayashi E; Miyoshi K; Ashizawa T; Okamoto A; Ogawa T; Katsumata S; Mihara A; Okabe M; Hirata T
    Jpn J Cancer Res; 1992 Jan; 83(1):113-20. PubMed ID: 1544867
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characteristics of antitumor activity of KW-2189, a novel water-soluble derivative of duocarmycin, against murine and human tumors.
    Kobayashi E; Okamoto A; Asada M; Okabe M; Nagamura S; Asai A; Saito H; Gomi K; Hirata T
    Cancer Res; 1994 May; 54(9):2404-10. PubMed ID: 8162588
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel antitumor antibiotic, KW-2189 is activated by carboxyl esterase and induces DNA strand breaks in human small cell lung cancer cells.
    Ogasawara H; Nishio K; Takeda Y; Ohmori T; Kubota N; Funayama Y; Ohira T; Kuraishi Y; Isogai Y; Saijo N
    Jpn J Cancer Res; 1994 Apr; 85(4):418-25. PubMed ID: 8200853
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The reversible DNA-alkylating activity of duocarmycin and its analogues.
    Asai A; Nagamura S; Saito H; Takahashi I; Nakano H
    Nucleic Acids Res; 1994 Jan; 22(1):88-93. PubMed ID: 8127659
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence-selective guanine reactivity by duocarmycin A.
    Mitchell MA; Weiland KL; Aristoff PA; Johnson PD; Dooley TP
    Chem Res Toxicol; 1993; 6(4):421-4. PubMed ID: 8374036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Duocarmycins, potent antitumor antibiotics produced by Streptomyces sp. structures and chemistry.
    Yasuzawa T; Muroi K; Ichimura M; Takahashi I; Ogawa T; Takahashi K; Sano H; Saitoh Y
    Chem Pharm Bull (Tokyo); 1995 Mar; 43(3):378-91. PubMed ID: 7774022
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA sequence selective adenine alkylation, mechanism of adduct repair, and in vivo antitumor activity of the novel achiral seco-amino-cyclopropylbenz[e]indolone analogue of duocarmycin AS-I-145.
    Kiakos K; Sato A; Asao T; McHugh PJ; Lee M; Hartley JA
    Mol Cancer Ther; 2007 Oct; 6(10):2708-18. PubMed ID: 17938264
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Concerted DNA recognition and novel site-specific alkylation by duocarmycin A with distamycin A.
    Yamamoto K; Sugiyama H; Kawanishi S
    Biochemistry; 1993 Feb; 32(4):1059-66. PubMed ID: 8424935
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
    Ichimura M; Ogawa T; Takahashi K; Mihara A; Takahashi I; Nakano H
    Oncol Res; 1993; 5(4-5):165-71. PubMed ID: 8305742
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient guanine alkylation through cooperative heterodimeric formation of duocarmycin A and distamycin A.
    Isomura M; Sugiyama H; Saito I
    Nucleic Acids Symp Ser; 1995; (34):47-8. PubMed ID: 8841545
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemistry of drug-induced DNA lesions.
    Saito I
    Toxicol Lett; 1993 Apr; 67(1-3):3-15. PubMed ID: 8451767
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro enhancement of antitumor activity of a water-soluble duocarmycin derivative, KW-2189, by caffeine-mediated DNA-repair inhibition in human lung cancer cells.
    Ogasawara H; Nishio K; Ishida T; Arioka H; Fukuoka K; Saijo N
    Jpn J Cancer Res; 1997 Nov; 88(11):1033-7. PubMed ID: 9439677
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole analogues of duocarmycin B2.
    Nagamura S; Kobayashi E; Gomi K; Saito H
    Bioorg Med Chem; 1996 Aug; 4(8):1379-91. PubMed ID: 8879561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distamycin A enhances the cytotoxicity of duocarmycin A and suppresses duocarmycin A-induced apoptosis in human lung carcinoma cells.
    Hirota M; Fujiwara T; Mineshita S; Sugiyama H; Teraoka H
    Int J Biochem Cell Biol; 2007; 39(5):988-96. PubMed ID: 17321782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antitumor activity of duocarmycin derivatives.
    Nagamura S; Kanda Y; Kobayashi E; Gomi K; Saito H
    Chem Pharm Bull (Tokyo); 1995 Sep; 43(9):1530-5. PubMed ID: 7586077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Duocarmycins--natures prodrugs?
    Searcey M
    Curr Pharm Des; 2002; 8(15):1375-89. PubMed ID: 12052214
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Substituent effects within the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065.
    Boger DL; Stauffer F; Hedrick MP
    Bioorg Med Chem Lett; 2001 Aug; 11(15):2021-4. PubMed ID: 11454471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site specific covalent alkylation of DNA by antitumor antibiotics, duocarmycin A and kapurimycin A3.
    Sugiyama H; Lam CK; Hosoda M; Saito I
    Nucleic Acids Symp Ser; 1991; (25):75-6. PubMed ID: 1842103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.