BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 7852344)

  • 1. Primer terminus stabilization at the phi 29 DNA polymerase active site. Mutational analysis of conserved motif KXY.
    Blasco MA; Méndez J; Lázaro JM; Blanco L; Salas M
    J Biol Chem; 1995 Feb; 270(6):2735-40. PubMed ID: 7852344
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phi 29 DNA polymerase active site. The conserved amino acid motif "Kx3NSxYG" is involved in template-primer binding and dNTP selection.
    Blasco MA; Lázaro JM; Blanco L; Salas M
    J Biol Chem; 1993 Aug; 268(22):16763-70. PubMed ID: 8344956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phi 29 DNA polymerase active site. Residue ASP249 of conserved amino acid motif "Dx2SLYP" is critical for synthetic activities.
    Blasco MA; Lázaro JM; Blanco L; Salas M
    J Biol Chem; 1993 Nov; 268(32):24106-13. PubMed ID: 8226957
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ø29 DNA polymerase residue Lys383, invariant at motif B of DNA-dependent polymerases, is involved in dNTP binding.
    Saturno J; Lázaro JM; Esteban FJ; Blanco L; Salas M
    J Mol Biol; 1997 Jun; 269(3):313-25. PubMed ID: 9199402
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR.
    Méndez J; Blanco L; Lázaro JM; Salas M
    J Biol Chem; 1994 Nov; 269(47):30030-8. PubMed ID: 7962004
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A highly conserved lysine residue in phi29 DNA polymerase is important for correct binding of the templating nucleotide during initiation of phi29 DNA replication.
    Truniger V; Lázaro JM; Blanco L; Salas M
    J Mol Biol; 2002 Apr; 318(1):83-96. PubMed ID: 12054770
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Two positively charged residues of phi29 DNA polymerase, conserved in protein-primed DNA polymerases, are involved in stabilisation of the incoming nucleotide.
    Truniger V; Lázaro JM; Salas M
    J Mol Biol; 2004 Jan; 335(2):481-94. PubMed ID: 14672657
    [TBL] [Abstract][Full Text] [Related]  

  • 8. phi29 DNA polymerase residue Phe128 of the highly conserved (S/T)Lx(2)h motif is required for a stable and functional interaction with the terminal protein.
    Rodríguez I; Lázaro JM; Salas M; de Vega M
    J Mol Biol; 2003 Jan; 325(1):85-97. PubMed ID: 12473453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Primer-terminus stabilization at the 3'-5' exonuclease active site of phi29 DNA polymerase. Involvement of two amino acid residues highly conserved in proofreading DNA polymerases.
    de Vega M; Lazaro JM; Salas M; Blanco L
    EMBO J; 1996 Mar; 15(5):1182-92. PubMed ID: 8605889
    [TBL] [Abstract][Full Text] [Related]  

  • 10. phi29 DNA polymerase residue Ser122, a single-stranded DNA ligand for 3'-5' exonucleolysis, is required to interact with the terminal protein.
    de Vega M; Blanco L; Salas M
    J Biol Chem; 1998 Oct; 273(44):28966-77. PubMed ID: 9786901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A conserved insertion in protein-primed DNA polymerases is involved in primer terminus stabilisation.
    Dufour E; Rodríguez I; Lázaro JM; de Vega M; Salas M
    J Mol Biol; 2003 Aug; 331(4):781-94. PubMed ID: 12909010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Site-directed mutagenesis at the Exo III motif of phi 29 DNA polymerase; overlapping structural domains for the 3'-5' exonuclease and strand-displacement activities.
    Soengas MS; Esteban JA; Lázaro JM; Bernad A; Blasco MA; Salas M; Blanco L
    EMBO J; 1992 Nov; 11(11):4227-37. PubMed ID: 1396603
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein.
    Dufour E; Méndez J; Lázaro JM; de Vega M; Blanco L; Salas M
    J Mol Biol; 2000 Dec; 304(3):289-300. PubMed ID: 11090274
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding.
    Blasco MA; Lázaro JM; Bernad A; Blanco L; Salas M
    J Biol Chem; 1992 Sep; 267(27):19427-34. PubMed ID: 1527062
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization and mapping of the pyrophosphorolytic activity of the phage phi 29 DNA polymerase. Involvement of amino acid motifs highly conserved in alpha-like DNA polymerases.
    Blasco MA; Bernad A; Blanco L; Salas M
    J Biol Chem; 1991 Apr; 266(12):7904-9. PubMed ID: 1850426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. phi 29 DNA polymerase residue Leu384, highly conserved in motif B of eukaryotic type DNA replicases, is involved in nucleotide insertion fidelity.
    Truniger V; Lázaro JM; de Vega M; Blanco L; Salas M
    J Biol Chem; 2003 Aug; 278(35):33482-91. PubMed ID: 12805385
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A DNA binding motif coordinating synthesis and degradation in proofreading DNA polymerases.
    Truniger V; Lázaro JM; Salas M; Blanco L
    EMBO J; 1996 Jul; 15(13):3430-41. PubMed ID: 8670845
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Motif A of bacteriophage T4 DNA polymerase: role in primer extension and DNA replication fidelity. Isolation of new antimutator and mutator DNA polymerases.
    Reha-Krantz LJ; Nonay RL
    J Biol Chem; 1994 Feb; 269(8):5635-43. PubMed ID: 8119900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and functional studies on phi 29 DNA polymerase.
    Blasco MA; Esteban JA; Méndez J; Blanco L; Salas M
    Chromosoma; 1992; 102(1 Suppl):S32-8. PubMed ID: 1291240
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal protein.
    Eisenbrandt R; Lázaro JM; Salas M; de Vega M
    Nucleic Acids Res; 2002 Mar; 30(6):1379-86. PubMed ID: 11884636
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.