BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 7853393)

  • 1. Intramolecular transmission of the ATP regulatory signal in Escherichia coli aspartate transcarbamylase: specific involvement of a clustered set of amino acid interactions at an interface between regulatory and catalytic subunits.
    De Staercke C; Van Vliet F; Xi XG; Rani CS; Ladjimi M; Jacobs A; Triniolles F; Hervé G; Cunin R
    J Mol Biol; 1995 Feb; 246(1):132-43. PubMed ID: 7853393
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intramolecular signal transmission in enterobacterial aspartate transcarbamylases II. Engineering co-operativity and allosteric regulation in the aspartate transcarbamylase of Erwinia herbicola.
    Cunin R; Rani CS; Van Vliet F; Wild JR; Wales M
    J Mol Biol; 1999 Dec; 294(5):1401-11. PubMed ID: 10600394
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The activation of Escherichia coli aspartate transcarbamylase by ATP. Specific involvement of helix H2' at the hydrophobic interface between the two domains of the regulatory chains.
    Xi XG; De Staercke C; Van Vliet F; Triniolles F; Jacobs A; Stas PP; Ladjimi MM; Simon V; Cunin R; Hervé G
    J Mol Biol; 1994 Sep; 242(2):139-49. PubMed ID: 8089837
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterotropic interactions in Escherichia coli aspartate transcarbamylase. Subunit interfaces involved in CTP inhibition and ATP activation.
    Xi XG; van Vliet F; Ladjimi MM; de Wannemaeker B; de Staercke C; Glansdorff N; Piérard A; Cunin R; Hervé G
    J Mol Biol; 1991 Aug; 220(3):789-99. PubMed ID: 1870132
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Divergent allosteric patterns verify the regulatory paradigm for aspartate transcarbamylase.
    Wales ME; Madison LL; Glaser SS; Wild JR
    J Mol Biol; 1999 Dec; 294(5):1387-400. PubMed ID: 10600393
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric regulation in a family of enterobacterial aspartate transcarbamylases: intramolecular transmission of regulatory signals in chimeric enzymes.
    Cunin R; Wales ME; Van Vliet F; De Staercke C; Scapozza L; Rani CS; Wild JR
    J Mol Biol; 1996 Sep; 262(2):258-69. PubMed ID: 8831792
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The N-terminus of the regulatory chain of Escherichia coli aspartate transcarbamoylase is important for both nucleotide binding and heterotropic effects.
    Sakash JB; Kantrowitz ER
    Biochemistry; 1998 Jan; 37(1):281-8. PubMed ID: 9425049
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of allosteric: zinc interdomain region of the regulatory subunit in the allosteric regulation of aspartate transcarbamoylase from Escherichia coli.
    Rastogi VK; Swanson R; Hartberg YM; Wales ME; Wild JR
    Arch Biochem Biophys; 1998 Jun; 354(2):215-24. PubMed ID: 9637729
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Weakening of the interface between adjacent catalytic chains promotes domain closure in Escherichia coli aspartate transcarbamoylase.
    Baker DP; Fetler L; Keiser RT; Vachette P; Kantrowitz ER
    Protein Sci; 1995 Feb; 4(2):258-67. PubMed ID: 7757014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the regulatory site of Escherichia coli aspartate transcarbamoylase by site-specific mutagenesis.
    Zhang Y; Kantrowitz ER
    Biochemistry; 1992 Jan; 31(3):792-8. PubMed ID: 1731936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Site-directed alterations to the geometry of the aspartate transcarbamoylase zinc domain: selective alteration to regulation by heterotropic ligands, isoelectric point, and stability in urea.
    Strang CJ; Wales ME; Brown DM; Wild JR
    Biochemistry; 1993 Apr; 32(16):4156-67. PubMed ID: 8476846
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterotropic interactions in aspartate transcarbamoylase: turning allosteric ATP activation into inhibition as a consequence of a single tyrosine to phenylalanine mutation.
    Van Vliet F; Xi XG; De Staercke C; de Wannemaeker B; Jacobs A; Cherfils J; Ladjimi MM; Hervé G; Cunin R
    Proc Natl Acad Sci U S A; 1991 Oct; 88(20):9180-3. PubMed ID: 1924381
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
    Stevens RC; Gouaux JE; Lipscomb WN
    Biochemistry; 1990 Aug; 29(33):7691-701. PubMed ID: 2271528
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synergistic inhibition of Escherichia coli aspartate transcarbamylase by CTP and UTP: binding studies using continuous-flow dialysis.
    England P; Hervé G
    Biochemistry; 1992 Oct; 31(40):9725-32. PubMed ID: 1390749
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of two purified mutants of Escherichia coli aspartate transcarbamylase with single amino acid substitutions.
    Silver RS; Daigneault JP; Teague PD; Kantrowitz ER
    J Mol Biol; 1983 Aug; 168(4):729-45. PubMed ID: 6350607
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aspartate transcarbamylase from the hyperthermophilic archaeon Pyrococcus abyssi. Insights into cooperative and allosteric mechanisms.
    Van Boxstael S; Maes D; Cunin R
    FEBS J; 2005 Jun; 272(11):2670-83. PubMed ID: 15943802
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discrimination between nucleotide effector responses of aspartate transcarbamoylase due to a single site substitution in the allosteric binding site.
    Corder TS; Wild JR
    J Biol Chem; 1989 May; 264(13):7425-30. PubMed ID: 2651439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Threonine 82 in the regulatory chain is important for nucleotide affinity and for the allosteric stabilization of Escherichia coli aspartate transcarbamoylase.
    Williams MK; Kantrowitz ER
    Biochim Biophys Acta; 1998 Dec; 1429(1):249-58. PubMed ID: 9920401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The allosteric activator Mg-ATP modifies the quaternary structure of the R-state of Escherichia coli aspartate transcarbamylase without altering the T<-->R equilibrium.
    Fetler L; Vachette P
    J Mol Biol; 2001 Jun; 309(3):817-32. PubMed ID: 11397099
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lysine-60 in the regulatory chain of Escherichia coli aspartate transcarbamoylase is important for the discrimination between CTP and ATP.
    Zhang Y; Kantrowitz ER
    Biochemistry; 1989 Sep; 28(18):7313-8. PubMed ID: 2510822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.