These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 7858500)

  • 1. Apoptosis induced by DNA topoisomerase I and II inhibitors in human leukemic HL-60 cells.
    Solary E; Bertrand R; Pommier Y
    Leuk Lymphoma; 1994 Sep; 15(1-2):21-32. PubMed ID: 7858500
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
    Bertrand R; Solary E; Jenkins J; Pommier Y
    Exp Cell Res; 1993 Aug; 207(2):388-97. PubMed ID: 7688316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of phorbol ester treatment on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells.
    Zwelling LA; Chan D; Hinds M; Mayes J; Silberman LE; Blick M
    Cancer Res; 1988 Dec; 48(23):6625-33. PubMed ID: 2846155
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Apoptosis of human leukemic cells induced by topoisomerase I and II inhibitors].
    Solary E; Dubrez L; Eymin B; Bertrand R; Pommier Y
    Bull Cancer; 1996 Mar; 83(3):205-12. PubMed ID: 8695922
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential GADD45, p21CIP1/WAF1, MCL-1 and topoisomerase II gene induction and secondary DNA fragmentation after camptothecin-induced DNA damage in two mutant p53 human colon cancer cell lines.
    Goldwasser F; Bae I; Fornace AJ; Pommier Y
    Oncol Res; 1996; 8(7-8):317-23. PubMed ID: 8938795
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bcl-2 prevents topoisomerase II inhibitor GL331-induced apoptosis is mediated by down-regulation of poly(ADP-ribose)polymerase activity.
    Kuo ML; Shen SC; Yang CH; Chuang SE; Cheng AL; Huang TS
    Oncogene; 1998 Oct; 17(17):2225-34. PubMed ID: 9811453
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Altered susceptibility of differentiating HL-60 cells to apoptosis induced by antitumor drugs.
    Del Bino G; Li X; Traganos F; Darzynkiewicz Z
    Leukemia; 1994 Feb; 8(2):281-8. PubMed ID: 7508535
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors.
    Dubrez L; Goldwasser F; Genne P; Pommier Y; Solary E
    Leukemia; 1995 Jun; 9(6):1013-24. PubMed ID: 7596166
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors.
    Solary E; Bertrand R; Kohn KW; Pommier Y
    Blood; 1993 Mar; 81(5):1359-68. PubMed ID: 8382972
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bax-alpha promotes apoptosis induced by cancer chemotherapy and accelerates the activation of caspase 3-like cysteine proteases in p53 double mutant B lymphoma Namalwa cells.
    Schmitt E; Steyaert A; Cimoli G; Bertrand R
    Cell Death Differ; 1998 Jun; 5(6):506-16. PubMed ID: 10200502
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA.
    Shou J; Ali-Osman F; Multani AS; Pathak S; Fedi P; Srivenugopal KS
    Oncogene; 2002 Jan; 21(6):878-89. PubMed ID: 11840333
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Topoisomerase inhibitor-induced apoptosis accompanied by down-regulation of Bcl-2 in human lung cancer cells.
    Oizumi S; Isobe H; Ogura S; Ishida T; Yamazaki K; Nishimura M; Kawakami Y; Dosaka-Akita H
    Anticancer Res; 2002; 22(6C):4029-37. PubMed ID: 12553028
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells.
    Jacob S; Aguado M; Fallik D; Praz F
    Cancer Res; 2001 Sep; 61(17):6555-62. PubMed ID: 11522654
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased cytotoxicity of an unusual DNA topoisomerase II inhibitor compound C-1305 toward HeLa cells with downregulated PARP-1 activity results from re-activation of the p53 pathway and modulation of mitotic checkpoints.
    Sabisz M; Wesierska-Gadek J; Skladanowski A
    Biochem Pharmacol; 2010 May; 79(10):1387-97. PubMed ID: 20067769
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I.
    Yu CC; Pan SL; Chao SW; Liu SP; Hsu JL; Yang YC; Li TK; Huang WJ; Guh JH
    Biochem Pharmacol; 2014 Aug; 90(3):320-30. PubMed ID: 24915421
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents.
    Gorczyca W; Gong J; Ardelt B; Traganos F; Darzynkiewicz Z
    Cancer Res; 1993 Jul; 53(13):3186-92. PubMed ID: 8319228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA topoisomerase II inhibition by peroxisomicine A(1) and its radical metabolite induces apoptotic cell death of HL-60 and HL-60/MX2 human leukemia cells.
    Lansiaux A; Laine W; Baldeyrou B; Mahieu C; Wattez N; Vezin H; Martinez FJ; PiƱeyro A; Bailly C
    Chem Res Toxicol; 2001 Jan; 14(1):16-24. PubMed ID: 11170504
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA topoisomerase I as a site of action for 10-hydroxycamptothecin in human promyelocytic leukemia cells.
    Ling YH; Andersson BS; Nelson JA
    Cancer Biochem Biophys; 1990 Jan; 11(1):23-30. PubMed ID: 2159843
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differentiation induction of human promyelocytic leukemia cells by 10-hydroxycamptothecin, a DNA topoisomerase I inhibitor.
    Ling YH; Tseng MT; Nelson JA
    Differentiation; 1991 Mar; 46(2):135-41. PubMed ID: 1648523
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.
    Jarvis WD; Turner AJ; Povirk LF; Traylor RS; Grant S
    Cancer Res; 1994 Apr; 54(7):1707-14. PubMed ID: 7511048
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.