BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 7872687)

  • 1. Role of cytochrome P-450 isoenzymes in the bioactivation of hydroxy anthraquinones.
    Fratta D; Simi S; Rainaldi G; Gervasi PG
    Anticancer Res; 1994; 14(6B):2597-603. PubMed ID: 7872687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Superoxide anion production and toxicity in V79 cells of six hydroxy-anthraquinones.
    Mian M; Fratta D; Rainaldi G; Simi S; Mariani T; Benetti D; Gervasi PG
    Anticancer Res; 1991; 11(3):1071-6. PubMed ID: 1653552
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C; Gelboin HV; Park SS; Pearce R; Parkinson A; Kupfer D
    Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes. Bioactivation to genotoxic metabolites.
    Mueller SO; Stopper H; Dekant W
    Drug Metab Dispos; 1998 Jun; 26(6):540-6. PubMed ID: 9616189
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
    Keyes SR; Fracasso PM; Heimbrook DC; Rockwell S; Sligar SG; Sartorelli AC
    Cancer Res; 1984 Dec; 44(12 Pt 1):5638-43. PubMed ID: 6437671
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.
    Foroozesh M; Primrose G; Guo Z; Bell LC; Alworth WL; Guengerich FP
    Chem Res Toxicol; 1997 Jan; 10(1):91-102. PubMed ID: 9074808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M; Shindo M; Shimada T
    Drug Metab Dispos; 2001 Feb; 29(2):200-5. PubMed ID: 11159812
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reduction of 3'-azido-2',3'-dideoxynucleosides to their 3'-amino metabolite is mediated by cytochrome P-450 and NADPH-cytochrome P-450 reductase in rat liver microsomes.
    Cretton EM; Sommadossi JP
    Drug Metab Dispos; 1993; 21(5):946-50. PubMed ID: 7902260
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of superoxide dismutase on hydroxylase activity and hydrogen peroxide formation in anthranilamide hydroxylation by a rat liver microsomal monooxygenase system.
    Ohta Y; Ishiguro I; Naito J; Shinohara R
    Biochem Int; 1984 May; 8(5):617-27. PubMed ID: 6477624
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.
    Buetler TM; Bammler TK; Hayes JD; Eaton DL
    Cancer Res; 1996 May; 56(10):2306-13. PubMed ID: 8625305
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytochrome P450 2B1-mediated one-electron reduction of adriamycin: a study with rat liver microsomes and purified enzymes.
    Goeptar AR; Te Koppele JM; Lamme EK; Piqué JM; Vermeulen NP
    Mol Pharmacol; 1993 Dec; 44(6):1267-77. PubMed ID: 8264564
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM; Oudshoorn MJ; Van Ommen B; Haenen GR; Van Bladeren PJ
    Chem Res Toxicol; 1996 Dec; 9(8):1249-56. PubMed ID: 8951226
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Denitrosation of the anti-cancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea catalyzed by microsomal glutathione S-transferase and cytochrome P450 monooxygenases.
    Weber GF; Waxman DJ
    Arch Biochem Biophys; 1993 Dec; 307(2):369-78. PubMed ID: 8274024
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H; Nakano M; Imai Y; Ueng YF; Guengerich FP; Shimada T
    Arch Biochem Biophys; 1996 Jan; 325(2):174-82. PubMed ID: 8561495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adriamycin activation and oxygen free radical formation in human breast tumor cells: protective role of glutathione peroxidase in adriamycin resistance.
    Sinha BK; Mimnaugh EG; Rajagopalan S; Myers CE
    Cancer Res; 1989 Jul; 49(14):3844-8. PubMed ID: 2544260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolic activation of the nitroaromatic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies.
    Berson A; Wolf C; Chachaty C; Fisch C; Fau D; Eugene D; Loeper J; Gauthier JC; Beaune P; Pompon D
    J Pharmacol Exp Ther; 1993 Apr; 265(1):366-72. PubMed ID: 8386241
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.
    Shaw PM; Hosea NA; Thompson DV; Lenius JM; Guengerich FP
    Arch Biochem Biophys; 1997 Dec; 348(1):107-15. PubMed ID: 9390180
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells.
    Schneider A; Schmalix WA; Siruguri V; de Groene EM; Horbach GJ; Kleingeist B; Lang D; Böcker R; Belloc C; Beaune P; Greim H; Doehmer J
    Arch Biochem Biophys; 1996 Aug; 332(2):295-304. PubMed ID: 8806738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of the flavoprotein inhibitor, diphenyleneiodonium sulfate, on ex vivo organic nitrate tolerance in the rat.
    Ratz JD; McGuire JJ; Anderson DJ; Bennett BM
    J Pharmacol Exp Ther; 2000 May; 293(2):569-77. PubMed ID: 10773030
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.