BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

374 related articles for article (PubMed ID: 7887900)

  • 1. Two sequences flanking the major autophosphorylation site of the insulin receptor are essential for tyrosine kinase activation.
    Leconte I; Clauser E
    Biochem J; 1995 Mar; 306 ( Pt 2)(Pt 2):465-72. PubMed ID: 7887900
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.
    Wilden PA; Kahn CR; Siddle K; White MF
    J Biol Chem; 1992 Aug; 267(23):16660-8. PubMed ID: 1322912
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The level of insulin receptor tyrosine kinase activity modulates the activities of phosphatidylinositol 3-kinase, microtubule-associated protein, and S6 kinases.
    Wilden PA; Kahn CR
    Mol Endocrinol; 1994 May; 8(5):558-67. PubMed ID: 8058065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Replacement of the conserved tyrosine 1210 by phenylalanine in the insulin receptor affects insulin-induced dephosphorylation of focal adhesion kinase but leaves other responses intact.
    Van der Zon GC; Ouwens DM; Dorrestijn J; Maassen JA
    Biochemistry; 1996 Aug; 35(32):10377-82. PubMed ID: 8756693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
    Ando A; Momomura K; Tobe K; Yamamoto-Honda R; Sakura H; Tamori Y; Kaburagi Y; Koshio O; Akanuma Y; Yazaki Y
    J Biol Chem; 1992 Jun; 267(18):12788-96. PubMed ID: 1618780
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-linked oligosaccharide chains of the insulin receptor beta subunit are essential for transmembrane signaling.
    Leconte I; Auzan C; Debant A; Rossi B; Clauser E
    J Biol Chem; 1992 Aug; 267(24):17415-23. PubMed ID: 1324936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Substitution of the insulin receptor transmembrane domain with the c-neu/erbB2 transmembrane domain constitutively activates the insulin receptor kinase in vitro.
    Yamada K; Goncalves E; Kahn CR; Shoelson SE
    J Biol Chem; 1992 Jun; 267(18):12452-61. PubMed ID: 1352286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytoplasmic juxtamembrane region of the insulin receptor: a critical role in ATP binding, endogenous substrate phosphorylation, and insulin-stimulated bioeffects in CHO cells.
    Backer JM; Schroeder GG; Cahill DA; Ullrich A; Siddle K; White MF
    Biochemistry; 1991 Jul; 30(26):6366-72. PubMed ID: 1647198
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin. Evidence that IRS-1 phosphorylation is not sufficient for normal insulin action.
    Krook A; Moller DE; Dib K; O'Rahilly S
    J Biol Chem; 1996 Mar; 271(12):7134-40. PubMed ID: 8636149
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies.
    Wilden PA; Siddle K; Haring E; Backer JM; White MF; Kahn CR
    J Biol Chem; 1992 Jul; 267(19):13719-27. PubMed ID: 1320027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The functions of the human insulin receptor are affected in different ways by mutation of each of the four N-glycosylation sites in the beta subunit.
    Leconte I; Carpentier JL; Clauser E
    J Biol Chem; 1994 Jul; 269(27):18062-71. PubMed ID: 8027066
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of an autoinhibitory domain in the insulin receptor tyrosine kinase.
    Filipek A; Soderling TR
    Mol Cell Biochem; 1993 Mar; 120(2):103-10. PubMed ID: 8487750
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of Ser(1275) and Ser(1309) as autophosphorylation sites of the human insulin receptor in intact cells.
    Tennagels N; Telting D; Parvaresch S; Maassen JA; Klein HW
    Biochem Biophys Res Commun; 2001 Mar; 282(2):387-93. PubMed ID: 11401470
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human insulin receptor mutated at threonine 1336 functions normally in Chinese hamster ovary cells.
    Ahn J; Rosen OM; Donner DB
    J Biol Chem; 1993 Aug; 268(22):16839-44. PubMed ID: 8393875
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The insulin receptor with phenylalanine replacing tyrosine-1146 provides evidence for separate signals regulating cellular metabolism and growth.
    Wilden PA; Backer JM; Kahn CR; Cahill DA; Schroeder GJ; White MF
    Proc Natl Acad Sci U S A; 1990 May; 87(9):3358-62. PubMed ID: 2159147
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substitution of the erbB-2 oncoprotein transmembrane domain activates the insulin receptor and modulates the action of insulin and insulin-receptor substrate 1.
    Cheatham B; Shoelson SE; Yamada K; Goncalves E; Kahn CR
    Proc Natl Acad Sci U S A; 1993 Aug; 90(15):7336-40. PubMed ID: 7688476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.
    De Fea K; Roth RA
    Biochemistry; 1997 Oct; 36(42):12939-47. PubMed ID: 9335553
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptor.
    Macaulay SL; Polites M; Hewish DR; Ward CW
    Biochem J; 1994 Oct; 303 ( Pt 2)(Pt 2):575-81. PubMed ID: 7980420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities.
    Couet J; Sargiacomo M; Lisanti MP
    J Biol Chem; 1997 Nov; 272(48):30429-38. PubMed ID: 9374534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin-stimulated phosphorylation of recombinant pp120/HA4, an endogenous substrate of the insulin receptor tyrosine kinase.
    Najjar SM; Philippe N; Suzuki Y; Ignacio GA; Formisano P; Accili D; Taylor SI
    Biochemistry; 1995 Jul; 34(29):9341-9. PubMed ID: 7626603
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.