These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 7891724)

  • 1. AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation.
    Datta K; Franke TF; Chan TO; Makris A; Yang SI; Kaplan DR; Morrison DK; Golemis EA; Tsichlis PN
    Mol Cell Biol; 1995 Apr; 15(4):2304-10. PubMed ID: 7891724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The SH2-like Akt homology (AH) domain of c-akt is present in multiple copies in the genome of vertebrate and invertebrate eucaryotes. Cloning and characterization of the Drosophila melanogaster c-akt homolog Dakt1.
    Franke TF; Tartof KD; Tsichlis PN
    Oncogene; 1994 Jan; 9(1):141-8. PubMed ID: 8302573
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase.
    Franke TF; Yang SI; Chan TO; Datta K; Kazlauskas A; Morrison DK; Kaplan DR; Tsichlis PN
    Cell; 1995 Jun; 81(5):727-36. PubMed ID: 7774014
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Akt activation by growth factors is a multiple-step process: the role of the PH domain.
    Bellacosa A; Chan TO; Ahmed NN; Datta K; Malstrom S; Stokoe D; McCormick F; Feng J; Tsichlis P
    Oncogene; 1998 Jul; 17(3):313-25. PubMed ID: 9690513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate.
    Franke TF; Kaplan DR; Cantley LC; Toker A
    Science; 1997 Jan; 275(5300):665-8. PubMed ID: 9005852
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2.
    Mitsuuchi Y; Johnson SW; Sonoda G; Tanno S; Golemis EA; Testa JR
    Oncogene; 1999 Sep; 18(35):4891-8. PubMed ID: 10490823
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation.
    Kohn AD; Takeuchi F; Roth RA
    J Biol Chem; 1996 Sep; 271(36):21920-6. PubMed ID: 8702995
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role for the adaptor protein Grb10 in the activation of Akt.
    Jahn T; Seipel P; Urschel S; Peschel C; Duyster J
    Mol Cell Biol; 2002 Feb; 22(4):979-91. PubMed ID: 11809791
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct activation mechanisms of protein kinase B by growth-factor stimulation and heat-shock treatment.
    Matsuzaki H; Yamamoto T; Kikkawa U
    Biochemistry; 2004 Apr; 43(14):4284-93. PubMed ID: 15065872
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells.
    Datta K; Bellacosa A; Chan TO; Tsichlis PN
    J Biol Chem; 1996 Nov; 271(48):30835-9. PubMed ID: 8940066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular modeling studies of the Akt PH domain and its interaction with phosphoinositides.
    Rong SB; Hu Y; Enyedy I; Powis G; Meuillet EJ; Wu X; Wang R; Wang S; Kozikowski AP
    J Med Chem; 2001 Mar; 44(6):898-908. PubMed ID: 11300871
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport.
    Kitamura T; Ogawa W; Sakaue H; Hino Y; Kuroda S; Takata M; Matsumoto M; Maeda T; Konishi H; Kikkawa U; Kasuga M
    Mol Cell Biol; 1998 Jul; 18(7):3708-17. PubMed ID: 9632753
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PKB/Akt interacts with inosine-5' monophosphate dehydrogenase through its pleckstrin homology domain.
    Ingley E; Hemmings BA
    FEBS Lett; 2000 Aug; 478(3):253-9. PubMed ID: 10930578
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate.
    Thomas CC; Deak M; Alessi DR; van Aalten DM
    Curr Biol; 2002 Jul; 12(14):1256-62. PubMed ID: 12176338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family.
    Laine J; Künstle G; Obata T; Noguchi M
    J Biol Chem; 2002 Feb; 277(5):3743-51. PubMed ID: 11707444
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues.
    Meuillet EJ; Mahadevan D; Vankayalapati H; Berggren M; Williams R; Coon A; Kozikowski AP; Powis G
    Mol Cancer Ther; 2003 Apr; 2(4):389-99. PubMed ID: 12700283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.
    Powell DJ; Hajduch E; Kular G; Hundal HS
    Mol Cell Biol; 2003 Nov; 23(21):7794-808. PubMed ID: 14560023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct specificity in the binding of inositol phosphates by pleckstrin homology domains of pleckstrin, RAC-protein kinase, diacylglycerol kinase and a new 130 kDa protein.
    Takeuchi H; Kanematsu T; Misumi Y; Sakane F; Konishi H; Kikkawa U; Watanabe Y; Katan M; Hirata M
    Biochim Biophys Acta; 1997 Dec; 1359(3):275-85. PubMed ID: 9434133
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Threonine phosphorylation of the beta 3 integrin cytoplasmic tail, at a site recognized by PDK1 and Akt/PKB in vitro, regulates Shc binding.
    Kirk RI; Sanderson MR; Lerea KM
    J Biol Chem; 2000 Oct; 275(40):30901-6. PubMed ID: 10896934
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors.
    Barnett SF; Defeo-Jones D; Fu S; Hancock PJ; Haskell KM; Jones RE; Kahana JA; Kral AM; Leander K; Lee LL; Malinowski J; McAvoy EM; Nahas DD; Robinson RG; Huber HE
    Biochem J; 2005 Jan; 385(Pt 2):399-408. PubMed ID: 15456405
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.