These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 7893471)

  • 21. Beta-galactosidases (Escherichia coli) with double substitutions show that Tyr-503 acts independently of Glu-461 but cooperatively with Glu-537.
    Roth NJ; Penner RM; Huber RE
    J Protein Chem; 2003 Nov; 22(7-8):663-8. PubMed ID: 14714733
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Multiple replacements establish the importance of tyrosine-503 in beta-galactosidase (Escherichia coli).
    Ring M; Huber RE
    Arch Biochem Biophys; 1990 Dec; 283(2):342-50. PubMed ID: 2125820
    [TBL] [Abstract][Full Text] [Related]  

  • 23. [Site-directed mutagenesis of Lac Z gene in Escherichia coli and the kinetic properties of the mutated enzymes].
    Chu X; Bai Y; Yuan J
    Wei Sheng Wu Xue Bao; 1994 Jun; 34(3):206-12. PubMed ID: 7975556
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Site specific mutants of beta-galactosidase show that Tyr-503 is unimportant in Mg2+ binding but that Glu-461 is very important and may be a ligand to Mg2+.
    Edwards RA; Cupples CG; Huber RE
    Biochem Biophys Res Commun; 1990 Aug; 171(1):33-7. PubMed ID: 2118347
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structure-reactivity relationships for beta-galactosidase (Escherichia coli, lac Z). 2. Reactions of the galactosyl-enzyme intermediate with alcohols and azide ion.
    Richard JP; Westerfeld JG; Lin S; Beard J
    Biochemistry; 1995 Sep; 34(37):11713-24. PubMed ID: 7547903
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Beta-galactosidase (Escherichia coli) has a second catalytically important Mg2+ site.
    Sutendra G; Wong S; Fraser ME; Huber RE
    Biochem Biophys Res Commun; 2007 Jan; 352(2):566-70. PubMed ID: 17126292
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mutational analysis of Thermus caldophilus GK24 beta-glycosidase: role of His119 in substrate binding and enzyme activity.
    Oh EJ; Lee YJ; Chol JJ; Seo MS; Lee MS; Kim GA; Kwon ST
    J Microbiol Biotechnol; 2008 Feb; 18(2):287-94. PubMed ID: 18309273
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structural basis for the altered activity of Gly794 variants of Escherichia coli beta-galactosidase.
    Juers DH; Hakda S; Matthews BW; Huber RE
    Biochemistry; 2003 Nov; 42(46):13505-11. PubMed ID: 14621996
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Substitution for Asn460 cripples β-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
    Wheatley RW; Kappelhoff JC; Hahn JN; Dugdale ML; Dutkoski MJ; Tamman SD; Fraser ME; Huber RE
    Arch Biochem Biophys; 2012 May; 521(1-2):51-61. PubMed ID: 22446164
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Functional properties of beta-galactosidase from mutant strain 13 PO of Escherichia coli.
    Deschavanne PJ; Viratelle OM; Yon JM
    Proc Natl Acad Sci U S A; 1978 Apr; 75(4):1892-6. PubMed ID: 25441
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Key amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic β-galactosidase.
    Laye VJ; Karan R; Kim JM; Pecher WT; DasSarma P; DasSarma S
    Proc Natl Acad Sci U S A; 2017 Nov; 114(47):12530-12535. PubMed ID: 29109294
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis.
    Zhang S; Bagshaw R; Hilson W; Oho Y; Hinek A; Clarke JT; Callahan JW
    Biochem J; 2000 Jun; 348 Pt 3(Pt 3):621-32. PubMed ID: 10839995
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effects of galactose and glucose on the hydrolysis reaction of a thermostable beta-galactosidase from Caldicellulosiruptor saccharolyticus.
    Park AR; Oh DK
    Appl Microbiol Biotechnol; 2010 Feb; 85(5):1427-35. PubMed ID: 19662397
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A solvent-isotope-effect study of proton transfer during catalysis by Escherichia coli (lacZ) beta-galactosidase.
    Selwood T; Sinnott ML
    Biochem J; 1990 Jun; 268(2):317-23. PubMed ID: 2114090
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry.
    Lo S; Dugdale ML; Jeerh N; Ku T; Roth NJ; Huber RE
    Protein J; 2010 Jan; 29(1):26-31. PubMed ID: 19936901
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Substrates with charged P1 residues are efficiently hydrolyzed by serine carboxypeptidases when S3-P1 interactions are facilitated.
    Olesen K; Breddam K
    Biochemistry; 1997 Oct; 36(40):12235-41. PubMed ID: 9315861
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Importance of hydroxyls at positions 3, 4, and 6 for binding to the "galactose" site of beta-galactosidase (Escherichia coli).
    Huber RE; Gaunt MT
    Arch Biochem Biophys; 1983 Jan; 220(1):263-71. PubMed ID: 6402986
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The properties of beta-galactosidases (Escherichia coli) with halogenated tyrosines.
    Ring M; Huber RE
    Biochem Cell Biol; 1993; 71(3-4):127-32. PubMed ID: 8398070
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Role of residues 104, 164, 166, 238 and 240 in the substrate profile of PER-1 beta-lactamase hydrolysing third-generation cephalosporins.
    Bouthors AT; Dagoneau-Blanchard N; Naas T; Nordmann P; Jarlier V; Sougakoff W
    Biochem J; 1998 Mar; 330 ( Pt 3)(Pt 3):1443-9. PubMed ID: 9494118
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli).
    Dugdale ML; Dymianiw DL; Minhas BK; D'Angelo I; Huber RE
    Biochem Cell Biol; 2010 Oct; 88(5):861-9. PubMed ID: 20921997
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.