BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

406 related articles for article (PubMed ID: 7895609)

  • 1. Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase.
    Masubuchi Y; Hosokawa S; Horie T; Suzuki T; Ohmori S; Kitada M; Narimatsu S
    Drug Metab Dispos; 1994; 22(6):909-15. PubMed ID: 7895609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
    Yoshimoto K; Echizen H; Chiba K; Tani M; Ishizaki T
    Br J Clin Pharmacol; 1995 Apr; 39(4):421-31. PubMed ID: 7640150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CYP1A2 and CYP2D6 4-hydroxylate propranolol and both reactions exhibit racial differences.
    Johnson JA; Herring VL; Wolfe MS; Relling MV
    J Pharmacol Exp Ther; 2000 Sep; 294(3):1099-105. PubMed ID: 10945865
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P450 enzymes involved in the enhancement of propranolol N-desisopropylation after repeated administration of propranolol in rats.
    Narimatsu S; Mochida M; Matsumoto T; Masubuchi Y; Horie T; Nagata K; Funae Y; Cho AK; Suzuki T
    Chem Biol Interact; 1996 Sep; 101(3):207-24. PubMed ID: 8870689
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    Ball SE; Ahern D; Scatina J; Kao J
    Br J Clin Pharmacol; 1997 Jun; 43(6):619-26. PubMed ID: 9205822
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of human cytochrome P450 isoforms involved in the 7-hydroxylation of chlorpromazine by human liver microsomes.
    Yoshii K; Kobayashi K; Tsumuji M; Tani M; Shimada N; Chiba K
    Life Sci; 2000; 67(2):175-84. PubMed ID: 10901285
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
    Suzuki T; Fujita S; Narimatsu S; Masubuchi Y; Tachibana M; Ohta S; Hirobe M
    FASEB J; 1992 Jan; 6(2):771-6. PubMed ID: 1537468
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193.
    Machinist JM; Mayer MD; Shet MS; Ferrero JL; Rodrigues AD
    Drug Metab Dispos; 1995 Oct; 23(10):1163-74. PubMed ID: 8654206
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
    Yamazaki H; Inoue K; Shaw PM; Checovich WJ; Guengerich FP; Shimada T
    J Pharmacol Exp Ther; 1997 Nov; 283(2):434-42. PubMed ID: 9353355
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.
    Botsch S; Gautier JC; Beaune P; Eichelbaum M; Kroemer HK
    Mol Pharmacol; 1993 Jan; 43(1):120-6. PubMed ID: 8423765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.
    von Moltke LL; Greenblatt DJ; Grassi JM; Granda BW; Venkatakrishnan K; Schmider J; Harmatz JS; Shader RI
    J Pharm Pharmacol; 1998 Sep; 50(9):997-1004. PubMed ID: 9811160
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of phenacetin O-deethylase activity by alpha-naphthoflavone in human liver microsomes.
    Nakajima M; Kobayashi K; Oshima K; Shimada N; Tokudome S; Chiba K; Yokoi T
    Xenobiotica; 1999 Sep; 29(9):885-98. PubMed ID: 10548449
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro.
    Störmer E; Brockmöller J; Roots I; Schmider J
    Psychopharmacology (Berl); 2000 Sep; 151(4):312-20. PubMed ID: 11026737
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regioselective contribution of the cytochrome P-450 2D subfamily to propranolol metabolism in rat liver microsomes.
    Masubuchi Y; Kagimoto N; Narimatsu S; Fujita S; Suzuki T
    Drug Metab Dispos; 1993; 21(6):1012-6. PubMed ID: 7905378
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is N-demethylated by cytochromes P450 2D6, 1A2 and 3A4--implications for susceptibility to Parkinson's disease.
    Coleman T; Ellis SW; Martin IJ; Lennard MS; Tucker GT
    J Pharmacol Exp Ther; 1996 May; 277(2):685-90. PubMed ID: 8627546
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective deficiency of debrisoquine 4-hydroxylase activity in mouse liver microsomes.
    Masubuchi Y; Iwasa T; Hosokawa S; Suzuki T; Horie T; Imaoka S; Funae Y; Narimatsu S
    J Pharmacol Exp Ther; 1997 Sep; 282(3):1435-41. PubMed ID: 9316857
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Involvement of a cytochrome P4502D subfamily in human liver microsomal bunitrolol 4-hydroxylation.
    Narimatsu S; Masubuchi Y; Hosokawa S; Ohmori S; Kitada M; Suzuki T
    Biol Pharm Bull; 1994 Jun; 17(6):803-7. PubMed ID: 7951142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Variable contribution of CYP2D6 to the N-dealkylation of S-(-)-propranolol by human liver microsomes.
    Rowland K; Ellis SW; Lennard MS; Tucker GT
    Br J Clin Pharmacol; 1996 Sep; 42(3):390-3. PubMed ID: 8877032
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.
    Yumibe N; Huie K; Chen KJ; Snow M; Clement RP; Cayen MN
    Biochem Pharmacol; 1996 Jan; 51(2):165-72. PubMed ID: 8615885
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.