These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Pentamidine transport and sensitivity in brucei-group trypanosomes. Damper D; Patton CL J Protozool; 1976 May; 23(2):349-56. PubMed ID: 6797 [TBL] [Abstract][Full Text] [Related]
4. Antitrypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-L-methionine. Byers TL; Bush TL; McCann PP; Bitonti AJ Biochem J; 1991 Mar; 274 ( Pt 2)(Pt 2):527-33. PubMed ID: 1672500 [TBL] [Abstract][Full Text] [Related]
5. Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter. de Koning HP; Jarvis SM Acta Trop; 2001 Dec; 80(3):245-50. PubMed ID: 11700182 [TBL] [Abstract][Full Text] [Related]
6. A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats. Anene BM; Ezeokonkwo RC; Mmesirionye TI; Tettey JN; Brock JM; Barrett MP; De Koning HP Parasitology; 2006 Jan; 132(Pt 1):127-33. PubMed ID: 16393361 [TBL] [Abstract][Full Text] [Related]
7. Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei. Carter NS; Berger BJ; Fairlamb AH J Biol Chem; 1995 Nov; 270(47):28153-7. PubMed ID: 7499305 [TBL] [Abstract][Full Text] [Related]
8. In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei. Bacchi CJ; Garofalo J; Mockenhaupt D; McCann PP; Diekema KA; Pegg AE; Nathan HC; Mullaney EA; Chunosoff L; Sjoerdsma A; Hutner SH Mol Biochem Parasitol; 1983 Mar; 7(3):209-25. PubMed ID: 6193423 [TBL] [Abstract][Full Text] [Related]
9. Effects of intermediates of methionine metabolism and nucleoside analogs on S-adenosylmethionine transport by Trypanosoma brucei brucei and a drug-resistant Trypanosoma brucei rhodesiense. Goldberg B; Rattendi D; Lloyd D; Sufrin JR; Bacchi CJ Biochem Pharmacol; 1998 Jul; 56(1):95-103. PubMed ID: 9698093 [TBL] [Abstract][Full Text] [Related]
10. Polyamine metabolism: a potential therapeutic target in trypanosomes. Bacchi CJ; Nathan HC; Hutner SH; McCann PP; Sjoerdsma A Science; 1980 Oct; 210(4467):332-4. PubMed ID: 6775372 [TBL] [Abstract][Full Text] [Related]
11. Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals. De Koning HP Mol Pharmacol; 2001 Mar; 59(3):586-92. PubMed ID: 11179454 [TBL] [Abstract][Full Text] [Related]
12. Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone). Bitonti AJ; Dumont JA; McCann PP Biochem J; 1986 Aug; 237(3):685-9. PubMed ID: 3800910 [TBL] [Abstract][Full Text] [Related]
13. Effects of polyamines on two strains of Trypanosoma brucei in infected rats and in vitro culture. Nishimura K; Yanase T; Araki N; Ohnishi Y; Kozaki S; Shima K; Asakura M; Samosomsuk W; Yamasaki S J Parasitol; 2006 Apr; 92(2):211-7. PubMed ID: 16729674 [TBL] [Abstract][Full Text] [Related]
14. Regulated expression of an essential allosteric activator of polyamine biosynthesis in African trypanosomes. Willert EK; Phillips MA PLoS Pathog; 2008 Oct; 4(10):e1000183. PubMed ID: 18949025 [TBL] [Abstract][Full Text] [Related]
15. Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. Munday JC; Eze AA; Baker N; Glover L; Clucas C; Aguinaga Andrés D; Natto MJ; Teka IA; McDonald J; Lee RS; Graf FE; Ludin P; Burchmore RJ; Turner CM; Tait A; MacLeod A; Mäser P; Barrett MP; Horn D; De Koning HP J Antimicrob Chemother; 2014 Mar; 69(3):651-63. PubMed ID: 24235095 [TBL] [Abstract][Full Text] [Related]
16. Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs. Nnadi CO; Ebiloma GU; Black JA; Nwodo NJ; Lemgruber L; Schmidt TJ; de Koning HP Molecules; 2019 Jan; 24(2):. PubMed ID: 30642032 [TBL] [Abstract][Full Text] [Related]
17. Pentamidine uptake and resistance in pathogenic protozoa: past, present and future. Bray PG; Barrett MP; Ward SA; de Koning HP Trends Parasitol; 2003 May; 19(5):232-9. PubMed ID: 12763430 [TBL] [Abstract][Full Text] [Related]
18. Regulation and function of polyamines in African trypanosomes. Willert E; Phillips MA Trends Parasitol; 2012 Feb; 28(2):66-72. PubMed ID: 22192816 [TBL] [Abstract][Full Text] [Related]