254 related articles for article (PubMed ID: 7910944)
1. Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.
Lu Q; Wright DD; Kamps MP
Mol Cell Biol; 1994 Jun; 14(6):3938-48. PubMed ID: 7910944
[TBL] [Abstract][Full Text] [Related]
2. An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1.
Calvo KR; Knoepfler P; McGrath S; Kamps MP
Oncogene; 1999 Dec; 18(56):8033-43. PubMed ID: 10637514
[TBL] [Abstract][Full Text] [Related]
3. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
Monica K; LeBrun DP; Dedera DA; Brown R; Cleary ML
Mol Cell Biol; 1994 Dec; 14(12):8304-14. PubMed ID: 7969166
[TBL] [Abstract][Full Text] [Related]
4. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.
Kamps MP; Look AT; Baltimore D
Genes Dev; 1991 Mar; 5(3):358-68. PubMed ID: 1672117
[TBL] [Abstract][Full Text] [Related]
5. Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias.
LeBrun DP; Cleary ML
Oncogene; 1994 Jun; 9(6):1641-7. PubMed ID: 8183558
[TBL] [Abstract][Full Text] [Related]
6. The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements.
Knoepfler PS; Kamps MP
Oncogene; 1997 May; 14(21):2521-31. PubMed ID: 9191052
[TBL] [Abstract][Full Text] [Related]
7. DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein.
Inaba T; Shapiro LH; Funabiki T; Sinclair AE; Jones BG; Ashmun RA; Look AT
Mol Cell Biol; 1994 May; 14(5):3403-13. PubMed ID: 8164688
[TBL] [Abstract][Full Text] [Related]
8. Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia.
Van Dijk MA; Voorhoeve PM; Murre C
Proc Natl Acad Sci U S A; 1993 Jul; 90(13):6061-5. PubMed ID: 8327485
[TBL] [Abstract][Full Text] [Related]
9. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
Lu Q; Knoepfler PS; Scheele J; Wright DD; Kamps MP
Mol Cell Biol; 1995 Jul; 15(7):3786-95. PubMed ID: 7791786
[TBL] [Abstract][Full Text] [Related]
10. New E2A/PBX1 fusion transcript in a patient with t(1;19)(q23;p13) acute lymphoblastic leukemia.
Numata S; Kato K; Horibe K
Leukemia; 1993 Sep; 7(9):1441-4. PubMed ID: 8103813
[TBL] [Abstract][Full Text] [Related]
11. Different molecular consequences of the 1;19 chromosomal translocation in childhood B-cell precursor acute lymphoblastic leukemia.
Privitera E; Kamps MP; Hayashi Y; Inaba T; Shapiro LH; Raimondi SC; Behm F; Hendershot L; Carroll AJ; Baltimore D
Blood; 1992 Apr; 79(7):1781-8. PubMed ID: 1348433
[TBL] [Abstract][Full Text] [Related]
12. DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation.
Kamps MP; Wright DD; Lu Q
Oncogene; 1996 Jan; 12(1):19-30. PubMed ID: 8552391
[TBL] [Abstract][Full Text] [Related]
13. The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias.
Hunger SP; Galili N; Carroll AJ; Crist WM; Link MP; Cleary ML
Blood; 1991 Feb; 77(4):687-93. PubMed ID: 1671560
[TBL] [Abstract][Full Text] [Related]
14. Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1.
Knoepfler PS; Calvo KR; Chen H; Antonarakis SE; Kamps MP
Proc Natl Acad Sci U S A; 1997 Dec; 94(26):14553-8. PubMed ID: 9405651
[TBL] [Abstract][Full Text] [Related]
15. Monoclonal antibodies specific to the acute lymphoblastic leukemia t(1;19)-associated E2A/pbx1 chimeric protein: characterization and diagnostic utility.
Sang BC; Shi L; Dias P; Liu L; Wei J; Wang ZX; Monell CR; Behm F; Gruenwald S
Blood; 1997 Apr; 89(8):2909-14. PubMed ID: 9108411
[TBL] [Abstract][Full Text] [Related]
16. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.
Chang CP; de Vivo I; Cleary ML
Mol Cell Biol; 1997 Jan; 17(1):81-8. PubMed ID: 8972188
[TBL] [Abstract][Full Text] [Related]
17. Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins.
Chang CP; Jacobs Y; Nakamura T; Jenkins NA; Copeland NG; Cleary ML
Mol Cell Biol; 1997 Oct; 17(10):5679-87. PubMed ID: 9315626
[TBL] [Abstract][Full Text] [Related]
18. [E2A gene in t(1;19)-ALL].
Hayashi Y
Nihon Rinsho; 1992 Jun; 50(6):1369-73. PubMed ID: 1355570
[TBL] [Abstract][Full Text] [Related]
19. E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice.
Kamps MP; Baltimore D
Mol Cell Biol; 1993 Jan; 13(1):351-7. PubMed ID: 8093327
[TBL] [Abstract][Full Text] [Related]
20. Establishment of a novel cell line (TS-2) of pre-B acute lymphoblastic leukemia with a t(1;19) not involving the E2A gene.
Yoshinari M; Imaizumi M; Eguchi M; Ogasawara M; Saito T; Suzuki H; Koizumi Y; Cui Y; Sato A; Saisho T; Ichinohasama R; Matsubara Y; Kamada N; Iinuma K
Cancer Genet Cytogenet; 1998 Mar; 101(2):95-102. PubMed ID: 9494609
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
