BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 7918411)

  • 1. Reactions catalyzed by 5-aminoimidazole ribonucleotide carboxylases from Escherichia coli and Gallus gallus: a case for divergent catalytic mechanisms.
    Firestine SM; Poon SW; Mueller EJ; Stubbe J; Davisson VJ
    Biochemistry; 1994 Oct; 33(39):11927-34. PubMed ID: 7918411
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme.
    Firestine SM; Davisson VJ
    Biochemistry; 1994 Oct; 33(39):11917-26. PubMed ID: 7918410
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical role of the Cryptococcus neoformans ADE2 protein in fungal de novo purine biosynthesis.
    Firestine SM; Misialek S; Toffaletti DL; Klem TJ; Perfect JR; Davisson VJ
    Arch Biochem Biophys; 1998 Mar; 351(1):123-34. PubMed ID: 9500840
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evidence for the direct transfer of the carboxylate of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N5-CAIR mutase.
    Meyer E; Kappock TJ; Osuji C; Stubbe J
    Biochemistry; 1999 Mar; 38(10):3012-8. PubMed ID: 10074353
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N5-carboxyaminoimidazole ribonucleotide: evidence for a new intermediate and two new enzymatic activities in the de novo purine biosynthetic pathway of Escherichia coli.
    Mueller EJ; Meyer E; Rudolph J; Davisson VJ; Stubbe J
    Biochemistry; 1994 Mar; 33(8):2269-78. PubMed ID: 8117684
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cloning of a chicken liver cDNA encoding 5-aminoimidazole ribonucleotide carboxylase and 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase by functional complementation of Escherichia coli pur mutants.
    Chen ZD; Dixon JE; Zalkin H
    Proc Natl Acad Sci U S A; 1990 Apr; 87(8):3097-101. PubMed ID: 1691501
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway.
    Meyer E; Leonard NJ; Bhat B; Stubbe J; Smith JM
    Biochemistry; 1992 Jun; 31(21):5022-32. PubMed ID: 1534690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase.
    Firestine SM; Wu W; Youn H; Davisson VJ
    Bioorg Med Chem; 2009 Jan; 17(2):794-803. PubMed ID: 19095456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily.
    Thoden JB; Kappock TJ; Stubbe J; Holden HM
    Biochemistry; 1999 Nov; 38(47):15480-92. PubMed ID: 10569930
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural organization of de novo purine biosynthesis enzymes in plants: 5-aminoimidazole ribonucleotide carboxylase and 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase cDNAs from Vigna aconitifolia.
    Chapman KA; Delauney AJ; Kim JH; Verma DP
    Plant Mol Biol; 1994 Jan; 24(2):389-95. PubMed ID: 8111040
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural analysis of the active site geometry of N5-carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
    Thoden JB; Holden HM; Firestine SM
    Biochemistry; 2008 Dec; 47(50):13346-53. PubMed ID: 19053251
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
    Škerlová J; Unterlass J; Göttmann M; Marttila P; Homan E; Helleday T; Jemth AS; Stenmark P
    J Biol Chem; 2020 Aug; 295(33):11656-11668. PubMed ID: 32571877
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis.
    Hoskins AA; Morar M; Kappock TJ; Mathews II; Zaugg JB; Barder TE; Peng P; Okamoto A; Ealick SE; Stubbe J
    Biochemistry; 2007 Mar; 46(10):2842-55. PubMed ID: 17298082
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Isatins Inhibit N
    Streeter CC; Lin Q; Firestine SM
    Biochemistry; 2019 Apr; 58(17):2260-2268. PubMed ID: 30964980
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical and structural studies of N5-carboxyaminoimidazole ribonucleotide mutase from the acidophilic bacterium Acetobacter aceti.
    Constantine CZ; Starks CM; Mill CP; Ransome AE; Karpowicz SJ; Francois JA; Goodman RA; Kappock TJ
    Biochemistry; 2006 Jul; 45(27):8193-208. PubMed ID: 16819818
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of a chemical modification on the hydrated adenosine intermediate produced by adenosine deaminase and a model reaction for a potential mechanism of action of 5-aminoimidazole ribonucleotide carboxylase.
    Groziak MP; Huan ZW; Ding H; Meng Z; Stevens WC; Robinson PD
    J Med Chem; 1997 Oct; 40(21):3336-45. PubMed ID: 9341908
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.
    Brugarolas P; Duguid EM; Zhang W; Poor CB; He C
    Acta Crystallogr D Biol Crystallogr; 2011 Aug; 67(Pt 8):707-15. PubMed ID: 21795812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Treponema denticola PurE Is a bacterial AIR carboxylase.
    Tranchimand S; Starks CM; Mathews II; Hockings SC; Kappock TJ
    Biochemistry; 2011 May; 50(21):4623-37. PubMed ID: 21548610
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway.
    Mathews II; Kappock TJ; Stubbe J; Ealick SE
    Structure; 1999 Nov; 7(11):1395-406. PubMed ID: 10574791
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase.
    Dewal MB; Firestine SM
    Biochemistry; 2013 Sep; 52(37):6559-67. PubMed ID: 23899325
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.