BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 7920658)

  • 1. Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism.
    Duprez L; Parma J; Van Sande J; Allgeier A; Leclère J; Schvartz C; Delisle MJ; Decoulx M; Orgiazzi J; Dumont J
    Nat Genet; 1994 Jul; 7(3):396-401. PubMed ID: 7920658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.
    Parma J; Duprez L; Van Sande J; Cochaux P; Gervy C; Mockel J; Dumont J; Vassart G
    Nature; 1993 Oct; 365(6447):649-51. PubMed ID: 8413627
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
    Parma J; Van Sande J; Swillens S; Tonacchera M; Dumont J; Vassart G
    Mol Endocrinol; 1995 Jun; 9(6):725-33. PubMed ID: 8592518
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Constitutively activating mutations of the thyrotropin receptor and thyroid disease.
    Führer D; Holzapfel HP; Wonerow P; Paschke R
    Eur J Med Res; 1996 Jul; 1(10):460-4. PubMed ID: 9438142
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Constitutively activating TSH receptor mutations as the cause of toxic thyroid adenoma, multinodular toxic goiter and autosomal dominant non autoimmune hyperthyroidism.
    Paschke R
    Exp Clin Endocrinol Diabetes; 1996; 104 Suppl 4():129-32. PubMed ID: 8981020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Somatic mutations in the VI transmembrane segment of the thyrotropin receptor constitutively activate cAMP signalling in thyroid hyperfunctioning adenomas.
    Porcellini A; Ciullo I; Pannain S; Fenzi G; Avvedimento E
    Oncogene; 1995 Sep; 11(6):1089-93. PubMed ID: 7566968
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Non-autoimmune hyperthyroidism and hyperfunctioning thyroid adenomas caused by activating mutation of the thyrotropin receptor].
    Kosugi S
    Nihon Rinsho; 2002 Feb; 60(2):291-6. PubMed ID: 11857916
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pathology of the TSH receptor.
    Duprez L; Parma J; Van Sande J; Rodien P; Sabine C; Abramowicz M; Dumont JE; Vassart G
    J Pediatr Endocrinol Metab; 1999 Apr; 12 Suppl 1():295-302. PubMed ID: 10698593
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TSH receptor mutation V509A causes familial hyperthyroidism by release of interhelical constraints between transmembrane helices TMH3 and TMH5.
    Karges B; Krause G; Homoki J; Debatin KM; de Roux N; Karges W
    J Endocrinol; 2005 Aug; 186(2):377-85. PubMed ID: 16079263
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Mutations in the thyrotropin receptor gene in the pathogenesis of toxic thyroid adenomas, toxic goiter nodules and autosomal dominant hyperthyroidism].
    Derwahl M
    Z Arztl Fortbild Qualitatssich; 1999 Apr; 93 Suppl 1():25-8. PubMed ID: 10355046
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the cAMP and MAPK pathways in the transformation of mouse 3T3 fibroblasts by a TSHR gene constitutively activated by point mutation.
    Du Villard JA; Wicker R; Crespo P; Russo D; Filetti S; Gutkind JS; Sarasin A; Suárez HG
    Oncogene; 2000 Oct; 19(42):4896-905. PubMed ID: 11039907
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas.
    Jaeschke H; Mueller S; Eszlinger M; Paschke R
    Clin Endocrinol (Oxf); 2010 Dec; 73(6):815-20. PubMed ID: 20846293
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
    Paschke R; Tonacchera M; Van Sande J; Parma J; Vassart G
    J Clin Endocrinol Metab; 1994 Dec; 79(6):1785-9. PubMed ID: 7989485
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Subclinical hyperthyroidism due to a thyrotropin receptor (TSHR) gene mutation (S505R).
    Pohlenz J; Pfarr N; Krüger S; Hesse V
    Acta Paediatr; 2006 Dec; 95(12):1685-7. PubMed ID: 17129985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Premature birth and low birth weight associated with nonautoimmune hyperthyroidism due to an activating thyrotropin receptor gene mutation.
    Vaidya B; Campbell V; Tripp JH; Spyer G; Hattersley AT; Ellard S
    Clin Endocrinol (Oxf); 2004 Jun; 60(6):711-8. PubMed ID: 15163335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Point mutations of the thyrotropin receptor determining structural requirements for its ability to bind thyrotropin and to stimulate adenylate cyclase activity.
    Gustavsson B; Westermark B; Heldin NE
    Biochem Biophys Res Commun; 1994 Mar; 199(2):612-8. PubMed ID: 8135801
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New pathophysiological mechanisms for hyperthyroidism.
    Vassart G
    Horm Res; 1997; 48 Suppl 4():47-50. PubMed ID: 9350447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia.
    Tonacchera M; Van Sande J; Cetani F; Swillens S; Schvartz C; Winiszewski P; Portmann L; Dumont JE; Vassart G; Parma J
    J Clin Endocrinol Metab; 1996 Feb; 81(2):547-54. PubMed ID: 8636266
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a new thyrotropin receptor germline mutation (Leu629Phe) in a family with neonatal onset of autosomal dominant nonautoimmune hyperthyroidism.
    Führer D; Wonerow P; Willgerodt H; Paschke R
    J Clin Endocrinol Metab; 1997 Dec; 82(12):4234-8. PubMed ID: 9398746
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas.
    Castro I; Lima L; Seoane R; Lado-Abeal J
    Thyroid; 2009 Jun; 19(6):645-9. PubMed ID: 19499991
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.