223 related articles for article (PubMed ID: 7932569)
1. Antipodal alpha-N-(methyl through decyl)-N-normetazocines (5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphans): in vitro and in vivo properties.
May EL; Aceto MD; Bowman ER; Bentley C; Martin BR; Harris LS; Medzihradsky F; Mattson MV; Jacobson AE
J Med Chem; 1994 Sep; 37(20):3408-18. PubMed ID: 7932569
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues.
May EL; Jacobson AE; Mattson MV; Traynor JR; Woods JH; Harris LS; Bowman ER; Aceto MD
J Med Chem; 2000 Dec; 43(26):5030-6. PubMed ID: 11150174
[TBL] [Abstract][Full Text] [Related]
3. DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity.
Gengo PJ; Pettit HO; O'Neill SJ; Wei K; McNutt R; Bishop MJ; Chang KJ
J Pharmacol Exp Ther; 2003 Dec; 307(3):1221-6. PubMed ID: 14534368
[TBL] [Abstract][Full Text] [Related]
4. 2,5-Dimethyl-2'-hydroxy-9 alpha- and 9 beta-(3-methylbutyl)-6,7-benzomorphans and N-substituted compounds in the 9 alpha-(3-methylbutyl) series: chemistry, pharmacology, and biochemistry.
Jacobson AE; Rice KC; Burke TR; Lupinacci L; Mattson MV; Aceto MD; Harris LS
J Pharm Sci; 1987 Mar; 76(3):248-52. PubMed ID: 3035172
[TBL] [Abstract][Full Text] [Related]
5. Some pharmacological properties of a newly synthesized 3-acetoxy-6 beta-acetylthio-10-oxo-N-cyclopropylmethyl-dihydronormorphine (KT-95).
Hosoki R; Niizawa S; Koike K; Sagara T; Kanematsu K; Takayanagi I
Arch Int Pharmacodyn Ther; 1996; 331(2):136-52. PubMed ID: 8937625
[TBL] [Abstract][Full Text] [Related]
6. Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists.
Katsura Y; Zhang X; Homma K; Rice KC; Calderon SN; Rothman RB; Yamamura HI; Davis P; Flippen-Anderson JL; Xu H; Becketts K; Foltz EJ; Porreca F
J Med Chem; 1997 Aug; 40(18):2936-47. PubMed ID: 9288176
[TBL] [Abstract][Full Text] [Related]
7. Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes.
Emmerson PJ; Liu MR; Woods JH; Medzihradsky F
J Pharmacol Exp Ther; 1994 Dec; 271(3):1630-7. PubMed ID: 7996478
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
Ananthan S; Johnson CA; Carter RL; Clayton SD; Rice KC; Xu H; Davis P; Porreca F; Rothman RB
J Med Chem; 1998 Jul; 41(15):2872-81. PubMed ID: 9667975
[TBL] [Abstract][Full Text] [Related]
9. Influence of spatial orientation of the C-6-OH group in ring C of morphine derivatives on opioid activity.
Friedmann T; Tóth Z; Hosztafi S; Simon CS; Makleit S; Fürst S
Arch Int Pharmacodyn Ther; 1994; 328(1):16-25. PubMed ID: 7893188
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence.
Neumeyer JL; Bidlack JM; Zong R; Bakthavachalam V; Gao P; Cohen DJ; Negus SS; Mello NK
J Med Chem; 2000 Jan; 43(1):114-22. PubMed ID: 10633042
[TBL] [Abstract][Full Text] [Related]
11. Effects of sigma ligands on the cloned mu-, delta- and kappa-opioid receptors co-expressed with G-protein-activated K+ (GIRK) channel in Xenopus oocytes.
Kobayashi T; Ikeda K; Ichikawa T; Togashi S; Kumanishi T
Br J Pharmacol; 1996 Sep; 119(1):73-80. PubMed ID: 8872359
[TBL] [Abstract][Full Text] [Related]
12. Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic.
De Souza EB; Schmidt WK; Kuhar MJ
J Pharmacol Exp Ther; 1988 Jan; 244(1):391-402. PubMed ID: 2826773
[TBL] [Abstract][Full Text] [Related]
13. 8-Carboxamidocyclazocine: a long-acting, novel benzomorphan.
Bidlack JM; Cohen DJ; McLaughlin JP; Lou R; Ye Y; Wentland MP
J Pharmacol Exp Ther; 2002 Jul; 302(1):374-80. PubMed ID: 12065740
[TBL] [Abstract][Full Text] [Related]
14. Opioid receptor ligands in the neonatal rat spinal cord: binding and in vitro depression of the nociceptive responses.
James IF; Bettaney J; Perkins MN; Ketchum SB; Dray A
Br J Pharmacol; 1990 Mar; 99(3):503-8. PubMed ID: 2158845
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and sigma binding properties of 1'- and 3'-halo- and 1',3'-dihalo-N-normetazocine analogues.
Danso-Danquah R; Bai X; Zhang X; Mascarella SW; Williams W; Sine B; Bowen WD; Carroll FI
J Med Chem; 1995 Jul; 38(15):2986-9. PubMed ID: 7636861
[TBL] [Abstract][Full Text] [Related]
16. Methylated analogues of methyl (R)-4-(3,4-dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as highly potent kappa-receptor agonists: stereoselective synthesis, opioid-receptor affinity, receptor selectivity, and functional studies.
Soukara S; Maier CA; Predoiu U; Ehret A; Jackisch R; Wünsch B
J Med Chem; 2001 Aug; 44(17):2814-26. PubMed ID: 11495592
[TBL] [Abstract][Full Text] [Related]
17. Enantiomeric N-substituted N-normetazocines: a comparative study of affinities at sigma, PCP, and mu opioid receptors.
Carroll FI; Abraham P; Parham K; Bai X; Zhang X; Brine GA; Mascarella SW; Martin BR; May EL; Sauss C
J Med Chem; 1992 Jul; 35(15):2812-8. PubMed ID: 1322987
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of (+)-(1'R,2'S) and (1'S,2'R)-6,11-dimethyl-1,2,3,4,5,6 -hexahydro-3-[[2'-(alkoxycarbonyl)-2'-phenylcyclopropyl]methyl]-2 ,6 -methano-3-benzazocin-8-ol. Comparison of the affinities for sigma 1 and opioid receptors with in the diastereoisomeric MPCB and CCB.
Ronsisvalle G; Prezzavento O; Pasquinucci L; Pappalardo MS; Marrazzo A; Vittorio F; Carboni L; Spampinato S
Farmaco; 1997; 52(6-7):471-6. PubMed ID: 9372600
[TBL] [Abstract][Full Text] [Related]
19. Selective protection and functionalization of morphine: synthesis and opioid receptor binding properties of 3-amino-3-desoxymorphine derivatives.
Wentland MP; Duan W; Cohen DJ; Bidlack JM
J Med Chem; 2000 Sep; 43(19):3558-65. PubMed ID: 11000010
[TBL] [Abstract][Full Text] [Related]
20. Evaluation of a series of N-alkyl benzomorphans in cell lines expressing transfected delta- and mu-opioid receptors.
Abood ME; Noel MA; Carter RC; Harris LS
Biochem Pharmacol; 1995 Sep; 50(6):851-9. PubMed ID: 7575648
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
