117 related articles for article (PubMed ID: 7932593)
1. Synthesis and 5-lipoxygenase inhibitory activities of some novel 2-substituted 5-benzofuran hydroxamic acids.
Ohemeng KA; Appollina MA; Nguyen VN; Schwender CF; Singer M; Steber M; Ansell J; Argentieri D; Hageman W
J Med Chem; 1994 Oct; 37(21):3663-7. PubMed ID: 7932593
[TBL] [Abstract][Full Text] [Related]
2. Novel bishydroxamic acids as 5-lipoxygenase inhibitors.
Ohemeng KA; Nguyen VN; Schwender CF; Singer M; Steber M; Ansell J; Hageman W
Bioorg Med Chem; 1994 Mar; 2(3):187-93. PubMed ID: 7922131
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and structure-activity relationships of a novel class of 5-lipoxygenase inhibitors. 2-(Phenylmethyl)-4-hydroxy-3,5-dialkylbenzofurans: the development of L-656,224.
Lau CK; Bélanger PC; Scheigetz J; Dufresne C; Williams HW; Maycock AL; Guindon Y; Bach T; Dallob AL; Denis D
J Med Chem; 1989 Jun; 32(6):1190-7. PubMed ID: 2542553
[TBL] [Abstract][Full Text] [Related]
4. Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors.
Satoh Y; Stanton JL; Hutchison AJ; Libby AH; Kowalski TJ; Lee WH; White DH; Kimble EF
J Med Chem; 1993 Nov; 36(23):3580-94. PubMed ID: 8246226
[TBL] [Abstract][Full Text] [Related]
5. Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid.
Greco MN; Hageman WE; Powell ET; Tighe JJ; Persico FJ
J Med Chem; 1992 Aug; 35(17):3180-3. PubMed ID: 1324317
[TBL] [Abstract][Full Text] [Related]
6. Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 7. Development of a series of substituted N-phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with enhanced hypocholesterolemic activity.
Trivedi BK; Purchase TS; Holmes A; Augelli-Szafran CE; Essenburg AD; Hamelehle KL; Stanfield RL; Bousley RF; Krause BR
J Med Chem; 1994 May; 37(11):1652-9. PubMed ID: 8201599
[TBL] [Abstract][Full Text] [Related]
7. Studies on 5-lipoxygenase inhibitors. I. Synthesis and 5-lipoxygenase-inhibitory activity of novel hydroxamic acid derivatives.
Yatabe T; Kawai Y; Oku T; Tanaka H
Chem Pharm Bull (Tokyo); 1998 Jun; 46(6):966-72. PubMed ID: 9658575
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 1. Synthesis and antimicrobial activity of (benzofuran-2-yl)(3-phenyl-3-methylcyclobutyl) ketoxime derivatives.
Koca M; Servi S; Kirilmis C; Ahmedzade M; Kazaz C; Ozbek B; Otük G
Eur J Med Chem; 2005 Dec; 40(12):1351-8. PubMed ID: 16129517
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of 3-substituted-benzofuran-2-carboxylic esters as a novel class of ischemic cell death inhibitors.
Suh J; Yi KY; Lee YS; Kim E; Yum EK; Yoo SE
Bioorg Med Chem Lett; 2010 Nov; 20(22):6362-5. PubMed ID: 20943387
[TBL] [Abstract][Full Text] [Related]
10. Benzofused hydroxamic acids: useful fragments for the preparation of histone deacetylase inhibitors. Part 2: 7-fluorobenzothiophenes and benzofurans.
Marastoni E; Bartoli S; Berettoni M; Cipollone A; Ettorre A; Fincham CI; Mauro S; Paris M; Porcelloni M; Bigioni M; Binaschi M; Nardelli F; Parlani M; Maggi CA; Paoli P; Rossi P; Fattori D
Bioorg Med Chem Lett; 2015 Apr; 25(7):1603-6. PubMed ID: 25746815
[TBL] [Abstract][Full Text] [Related]
11. Design and synthesis of novel metalloproteinase inhibitors.
Nakatani S; Ikura M; Yamamoto S; Nishita Y; Itadani S; Habashita H; Sugiura T; Ogawa K; Ohno H; Takahashi K; Nakai H; Toda M
Bioorg Med Chem; 2006 Aug; 14(15):5402-22. PubMed ID: 16621578
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and CYP26A1 inhibitory activity of 1-[benzofuran-2-yl-(4-alkyl/aryl-phenyl)-methyl]-1H-triazoles.
Pautus S; Yee SW; Jayne M; Coogan MP; Simons C
Bioorg Med Chem; 2006 Jun; 14(11):3643-53. PubMed ID: 16458519
[TBL] [Abstract][Full Text] [Related]
13. 1,4-Dihydronaphthoquinones, hydroindoloquinones, benzofurans, and benzothiophenes as inhibitors of 5-lipoxygenase. Synthesis and structure-activity studies.
Yamashita A; Schaub RG; Bach MK; White GJ; Toy A; Ghazal NB; Burdick MD; Brashler JR; Holm MS
J Med Chem; 1990 Feb; 33(2):775-81. PubMed ID: 2153828
[TBL] [Abstract][Full Text] [Related]
14. Antioxidant-based inhibitors of leukotriene biosynthesis. The discovery of 6-[1-[2-(hydroxymethyl)phenyl]-1-propen-3-yl]-2,3-dihydro-5- benzofuranol, a potent topical antiinflammatory agent.
Hammond ML; Zambias RA; Chang MN; Jensen NP; McDonald J; Thompson K; Boulton DA; Kopka IE; Hand KM; Opas EE
J Med Chem; 1990 Mar; 33(3):908-18. PubMed ID: 2308140
[TBL] [Abstract][Full Text] [Related]
15. Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase.
Lau CK; Bélanger PC; Dufresne C; Scheigetz J; Therien M; Fitzsimmons B; Young RN; Ford-Hutchinson AW; Riendeau D; Denis D
J Med Chem; 1992 Apr; 35(7):1299-318. PubMed ID: 1313879
[TBL] [Abstract][Full Text] [Related]
16. 5-Lipoxygenase inhibitors: the synthesis and structure-activity relationships of a series of 1-phenyl-3-pyrazolidinones.
Hlasta DJ; Casey FB; Ferguson EW; Gangell SJ; Heimann MR; Jaeger EP; Kullnig RK; Gordon RJ
J Med Chem; 1991 May; 34(5):1560-70. PubMed ID: 1903450
[TBL] [Abstract][Full Text] [Related]
17. Bicyclic N-hydroxyurea inhibitors of 5-lipoxygenase: pharmacodynamic, pharmacokinetic, and in vitro metabolic studies characterizing N-hydroxy-N-(2,3-dihydro-6-(phenylmethoxy)-3-benzofuranyl)urea.
Adams JL; Garigipati RS; Sorenson M; Schmidt SJ; Brian WR; Newton JF; Tyrrell KA; Garver E; Yodis LA; Chabot-Fletcher M; Tzimas M; Webb EF; Breton JJ; Griswold DE
J Med Chem; 1996 Dec; 39(26):5035-46. PubMed ID: 8978834
[TBL] [Abstract][Full Text] [Related]
18. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors.
Crawley GC; Dowell RI; Edwards PN; Foster SJ; McMillan RM; Walker ER; Waterson D; Bird TG; Bruneau P; Giroaeau JM
J Med Chem; 1992 Jul; 35(14):2600-9. PubMed ID: 1321908
[TBL] [Abstract][Full Text] [Related]
19. 7-Substituted 2-phenyl-benzofurans as ER beta selective ligands.
Collini MD; Kaufman DH; Manas ES; Harris HA; Henderson RA; Xu ZB; Unwalla RJ; Miller CP
Bioorg Med Chem Lett; 2004 Oct; 14(19):4925-9. PubMed ID: 15341953
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and Evaluation of Novel Benzofuran Derivatives as Selective SIRT2 Inhibitors.
Zhou Y; Cui H; Yu X; Peng T; Wang G; Wen X; Sun Y; Liu S; Zhang S; Hu L; Wang L
Molecules; 2017 Aug; 22(8):. PubMed ID: 28805748
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]