BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 7937748)

  • 1. One disulfide bond in front of the second heavy chain constant region is necessary and sufficient for effector functions of human IgG3 without a genetic hinge.
    Michaelsen TE; Brekke OH; Aase A; Sandin RH; Bremnes B; Sandlie I
    Proc Natl Acad Sci U S A; 1994 Sep; 91(20):9243-7. PubMed ID: 7937748
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The extended hinge region of IgG3 is not required for high phagocytic capacity mediated by Fc gamma receptors, but the heavy chains must be disulfide bonded.
    Aase A; Sandlie I; Norderhaug L; Brekke OH; Michaelsen TE
    Eur J Immunol; 1993 Jul; 23(7):1546-51. PubMed ID: 8325331
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of complement by an IgG molecule without a genetic hinge.
    Brekke OH; Michaelsen TE; Sandin R; Sandlie I
    Nature; 1993 Jun; 363(6430):628-30. PubMed ID: 8510754
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antibody dependent cell-mediated cytotoxicity induced by chimeric mouse-human IgG subclasses and IgG3 antibodies with altered hinge region.
    Michaelsen TE; Aase A; Norderhaug L; Sandlie I
    Mol Immunol; 1992 Mar; 29(3):319-26. PubMed ID: 1557042
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human IgG3 can adopt the disulfide bond pattern characteristic for IgG1 without resembling it in complement mediated cell lysis.
    Brekke OH; Bremnes B; Sandin R; Aase A; Michaelsen TE; Sandlie I
    Mol Immunol; 1993 Nov; 30(16):1419-25. PubMed ID: 8232327
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequence of ovine Ig gamma 2 constant region heavy chain cDNA and molecular modelling of ruminant IgG isotypes.
    Clarkson CA; Beale D; Coadwell JW; Symons DB
    Mol Immunol; 1993 Sep; 30(13):1195-204. PubMed ID: 8413324
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino acid differences in the N-terminus of C(H)2 influence the relative abilities of IgG2 and IgG3 to activate complement.
    Sensel MG; Kane LM; Morrison SL
    Mol Immunol; 1997 Oct; 34(14):1019-29. PubMed ID: 9488053
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancement of complement activation and cytolysis of human IgG3 by deletion of hinge exons.
    Michaelsen TE; Aase A; Westby C; Sandlie I
    Scand J Immunol; 1990 Nov; 32(5):517-28. PubMed ID: 2125362
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The influence of the hinge region length in binding of human IgG to human Fcgamma receptors.
    Redpath S; Michaelsen TE; Sandlie I; Clark MR
    Hum Immunol; 1998 Nov; 59(11):720-7. PubMed ID: 9796740
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antigen binding and biological activities of engineered mutant chimeric antibodies with human tumor specificities.
    Gillies SD; Wesolowski JS
    Hum Antibodies Hybridomas; 1990; 1(1):47-54. PubMed ID: 2129419
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of inter-heavy and light chain disulfide bonds in the effector functions of human immunoglobulin IgG1.
    Dorai H; Wesolowski JS; Gillies SD
    Mol Immunol; 1992 Dec; 29(12):1487-91. PubMed ID: 1454066
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The structural requirements for complement activation by IgG: does it hinge on the hinge?
    Brekke OH; Michaelsen TE; Sandlie I
    Immunol Today; 1995 Feb; 16(2):85-90. PubMed ID: 7888072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chimeric mouse human IgG3 antibodies with an IgG4-like hinge region induce complement-mediated lysis more efficiently than IgG3 with normal hinge.
    Norderhaug L; Brekke OH; Bremnes B; Sandin R; Aase A; Michaelsen TE; Sandlie I
    Eur J Immunol; 1991 Oct; 21(10):2379-84. PubMed ID: 1915551
    [TBL] [Abstract][Full Text] [Related]  

  • 14. C1q binding to chimeric monoclonal IgG3 antibodies consisting of mouse variable regions and human constant regions with shortened hinge containing 15 to 47 amino acids.
    Sandlie I; Aase A; Westby C; Michaelsen TE
    Eur J Immunol; 1989 Sep; 19(9):1599-603. PubMed ID: 2792180
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human IgG isotype-specific amino acid residues affecting complement-mediated cell lysis and phagocytosis.
    Brekke OH; Michaelsen TE; Aase A; Sandin RH; Sandlie I
    Eur J Immunol; 1994 Oct; 24(10):2542-7. PubMed ID: 7925582
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mapping and comparison of the interaction sites on the Fc region of IgG responsible for triggering antibody dependent cellular cytotoxicity (ADCC) through different types of human Fc gamma receptor.
    Sarmay G; Lund J; Rozsnyay Z; Gergely J; Jefferis R
    Mol Immunol; 1992 May; 29(5):633-9. PubMed ID: 1533898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies of aglycosylated chimeric mouse-human IgG. Role of carbohydrate in the structure and effector functions mediated by the human IgG constant region.
    Tao MH; Morrison SL
    J Immunol; 1989 Oct; 143(8):2595-601. PubMed ID: 2507634
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The inter-heavy chain disulfide bonds of IgG4 are in equilibrium with intra-chain disulfide bonds.
    Schuurman J; Perdok GJ; Gorter AD; Aalberse RC
    Mol Immunol; 2001 Jan; 38(1):1-8. PubMed ID: 11483205
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The hinge as a spacer contributes to covalent assembly and is required for function of IgG.
    Coloma MJ; Trinh KR; Wims LA; Morrison SL
    J Immunol; 1997 Jan; 158(2):733-40. PubMed ID: 8992989
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inheritance of a large deletion within the human immunoglobulin heavy chain constant region gene complex and immunological implications.
    Hendriks RW; van Tol MJ; de Lange GG; Schuurman RK
    Scand J Immunol; 1989 May; 29(5):535-41. PubMed ID: 2567054
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.