These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 7949373)

  • 1. Involvement of CYP2D6, CYP3A4, and other cytochrome P-450 isozymes in N-dealkylation reactions.
    Coutts RT; Su P; Baker GB
    J Pharmacol Toxicol Methods; 1994 Aug; 31(4):177-86. PubMed ID: 7949373
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase.
    Masubuchi Y; Hosokawa S; Horie T; Suzuki T; Ohmori S; Kitada M; Narimatsu S
    Drug Metab Dispos; 1994; 22(6):909-15. PubMed ID: 7895609
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol.
    Fang J; Baker GB; Silverstone PH; Coutts RT
    Cell Mol Neurobiol; 1997 Apr; 17(2):227-33. PubMed ID: 9140699
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol.
    Pan LP; De Vriendt C; Belpaire FM
    Pharmacogenetics; 1998 Oct; 8(5):383-9. PubMed ID: 9825830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of three cytochrome P450 isozymes involved in N-demethylation of citalopram enantiomers in human liver microsomes.
    Rochat B; Amey M; Gillet M; Meyer UA; Baumann P
    Pharmacogenetics; 1997 Feb; 7(1):1-10. PubMed ID: 9110356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Involvement of CYP3A4 in the metabolism of bromperidol in vitro.
    Sato S; Someya T; Shioiri O; Koitabashi T; Inoue Y
    Pharmacol Toxicol; 2000 Mar; 86(3):145-8. PubMed ID: 10752674
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Capillary electrophoretic investigation of the enantioselective metabolism of propafenone by human cytochrome P-450 SUPERSOMES: Evidence for atypical kinetics by CYP2D6 and CYP3A4.
    Afshar M; Thormann W
    Electrophoresis; 2006 Apr; 27(8):1526-36. PubMed ID: 16609933
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stereoselective differences in the cytochrome P450-dependent dealkylation and demethylenation of N-methyl-benzodioxolyl-butanamine (MBDB, Eden) enantiomers.
    Meyer MR; Peters FT; Maurer HH
    Biochem Pharmacol; 2009 Jun; 77(11):1725-34. PubMed ID: 19428327
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human buprenorphine N-dealkylation is catalyzed by cytochrome P450 3A4.
    Kobayashi K; Yamamoto T; Chiba K; Tani M; Shimada N; Ishizaki T; Kuroiwa Y
    Drug Metab Dispos; 1998 Aug; 26(8):818-21. PubMed ID: 9698298
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro.
    Störmer E; Brockmöller J; Roots I; Schmider J
    Psychopharmacology (Berl); 2000 Sep; 151(4):312-20. PubMed ID: 11026737
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes.
    Crewe HK; Ellis SW; Lennard MS; Tucker GT
    Biochem Pharmacol; 1997 Jan; 53(2):171-8. PubMed ID: 9037249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.
    Botsch S; Gautier JC; Beaune P; Eichelbaum M; Kroemer HK
    Mol Pharmacol; 1993 Jan; 43(1):120-6. PubMed ID: 8423765
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is N-demethylated by cytochromes P450 2D6, 1A2 and 3A4--implications for susceptibility to Parkinson's disease.
    Coleman T; Ellis SW; Martin IJ; Lennard MS; Tucker GT
    J Pharmacol Exp Ther; 1996 May; 277(2):685-90. PubMed ID: 8627546
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs.
    Brandes LJ; Queen GM; LaBella FS
    Cancer Chemother Pharmacol; 2000; 45(4):298-304. PubMed ID: 10755318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of imipramine in vitro by isozyme CYP2D6 expressed in a human cell line, and observations on metabolite stability.
    Coutts RT; Su P; Baker GB; Daneshtalab M
    J Chromatogr; 1993 Jun; 615(2):265-72. PubMed ID: 8335704
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
    Bakken GV; Molden E; Knutsen K; Lunder N; Hermann M
    Drug Metab Dispos; 2012 Sep; 40(9):1778-84. PubMed ID: 22688609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Application of liquid chromatography/mass spectrometry in accelerating the identification of human liver cytochrome P450 isoforms involved in the metabolism of iloperidone.
    Mutlib AE; Klein JT
    J Pharmacol Exp Ther; 1998 Sep; 286(3):1285-93. PubMed ID: 9732390
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation.
    Tateishi T; Krivoruk Y; Ueng YF; Wood AJ; Guengerich FP; Wood M
    Anesth Analg; 1996 Jan; 82(1):167-72. PubMed ID: 8712396
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol.
    Pan LP; Wijnant P; De Vriendt C; Rosseel MT; Belpaire FM
    Br J Clin Pharmacol; 1997 Dec; 44(6):557-64. PubMed ID: 9431831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of human cytochrome P450 isoforms interacting with pimozide.
    Desta Z; Kerbusch T; Soukhova N; Richard E; Ko JW; Flockhart DA
    J Pharmacol Exp Ther; 1998 May; 285(2):428-37. PubMed ID: 9580580
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.