BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

484 related articles for article (PubMed ID: 7954469)

  • 1. Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
    Dirven HA; van Ommen B; van Bladeren PJ
    Cancer Res; 1994 Dec; 54(23):6215-20. PubMed ID: 7954469
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of human glutathione S-transferase isoenzymes in the formation of glutathione conjugates of the alkylating cytostatic drug thiotepa.
    Dirven HA; Dictus EL; Broeders NL; van Ommen B; van Bladeren PJ
    Cancer Res; 1995 Apr; 55(8):1701-6. PubMed ID: 7712478
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases.
    Dirven HA; Megens L; Oudshoorn MJ; Dingemanse MA; van Ommen B; van Bladeren PJ
    Chem Res Toxicol; 1995; 8(7):979-86. PubMed ID: 8555414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glutathione conjugation with phosphoramide mustard and cyclophosphamide. A mechanistic study using tandem mass spectrometry.
    Yuan ZM; Smith PB; Brundrett RB; Colvin M; Fenselau C
    Drug Metab Dispos; 1991; 19(3):625-9. PubMed ID: 1680629
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.
    Bogaards JJ; Venekamp JC; van Bladeren PJ
    Chem Res Toxicol; 1997 Mar; 10(3):310-7. PubMed ID: 9084911
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of human glutathione S-transferases in the inactivation of reactive metabolites of clozapine.
    Dragovic S; Boerma JS; van Bergen L; Vermeulen NP; Commandeur JN
    Chem Res Toxicol; 2010 Sep; 23(9):1467-76. PubMed ID: 20849150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.
    Geroni C; Marchini S; Cozzi P; Galliera E; Ragg E; Colombo T; Battaglia R; Howard M; D'Incalci M; Broggini M
    Cancer Res; 2002 Apr; 62(8):2332-6. PubMed ID: 11956092
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selectivity of rat and human glutathione S-transferases in activation of ethylene dibromide by glutathione conjugation and DNA binding and induction of unscheduled DNA synthesis in human hepatocytes.
    Cmarik JL; Inskeep PB; Meredith MJ; Meyer DJ; Ketterer B; Guengerich FP
    Cancer Res; 1990 May; 50(9):2747-52. PubMed ID: 2328501
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The interaction of glutathione with 4-hydroxycyclophosphamide and phosphoramide mustard, studied by 31P nuclear magnetic resonance spectroscopy.
    Dirven HA; Venekamp JC; van Ommen B; van Bladeren PJ
    Chem Biol Interact; 1994 Dec; 93(3):185-96. PubMed ID: 7923439
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of human mu or alpha class glutathione S-transferases in stably transfected human MCF-7 breast cancer cells: effect on cellular sensitivity to cytotoxic agents.
    Townsend AJ; Tu CP; Cowan KH
    Mol Pharmacol; 1992 Feb; 41(2):230-6. PubMed ID: 1538704
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa.
    Srivastava SK; Singhal SS; Hu X; Awasthi YC; Zimniak P; Singh SV
    Arch Biochem Biophys; 1999 Jun; 366(1):89-94. PubMed ID: 10334868
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives.
    Fujioka K; Casida JE
    Chem Res Toxicol; 2007 Aug; 20(8):1211-7. PubMed ID: 17645302
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced expressions of glucose-6-phosphate dehydrogenase and cytosolic aldehyde dehydrogenase and elevation of reduced glutathione level in cyclophosphamide-resistant human leukemia cells.
    Tsukamoto N; Chen J; Yoshida A
    Blood Cells Mol Dis; 1998 Jun; 24(2):231-8. PubMed ID: 9714700
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conversion of 4-hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein mediated by bifunctional catalysis.
    Low JE; Borch RF; Sladek NE
    Cancer Res; 1982 Mar; 42(3):830-7. PubMed ID: 7059981
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glutathione-dependent biotransformation of the alkylating drug thiotepa and transport of its metabolite monoglutathionylthiotepa in human MCF-7 breast cancer cells.
    Cnubben NH; Rommens AJ; Oudshoorn MJ; Van Bladeren PJ
    Cancer Res; 1998 Oct; 58(20):4616-23. PubMed ID: 9788613
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specificity of isozymes of murine hepatic glutathione S-transferase for the conjugation of glutathione with L-phenylalanine mustard.
    Bolton MG; Colvin OM; Hilton J
    Cancer Res; 1991 May; 51(9):2410-5. PubMed ID: 2015603
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases.
    Tang W; Borel AG; Abbott FS
    Drug Metab Dispos; 1996 Apr; 24(4):436-46. PubMed ID: 8801059
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glutathione S-transferase enzyme expression in hematopoietic cell lines implies a differential protective role for T1 and A1 isoenzymes in erythroid and for M1 in lymphoid lineages.
    Wang L; Groves MJ; Hepburn MD; Bowen DT
    Haematologica; 2000 Jun; 85(6):573-9. PubMed ID: 10870112
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of glutathione in cellular resistance to alkylating agents.
    Colvin OM; Friedman HS; Gamcsik MP; Fenselau C; Hilton J
    Adv Enzyme Regul; 1993; 33():19-26. PubMed ID: 8356908
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2).
    Paumi CM; Smitherman PK; Townsend AJ; Morrow CS
    Biochemistry; 2004 Mar; 43(8):2345-52. PubMed ID: 14979731
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.