280 related articles for article (PubMed ID: 7969166)
1. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
Monica K; LeBrun DP; Dedera DA; Brown R; Cleary ML
Mol Cell Biol; 1994 Dec; 14(12):8304-14. PubMed ID: 7969166
[TBL] [Abstract][Full Text] [Related]
2. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.
Chang CP; de Vivo I; Cleary ML
Mol Cell Biol; 1997 Jan; 17(1):81-8. PubMed ID: 8972188
[TBL] [Abstract][Full Text] [Related]
3. Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.
Lu Q; Wright DD; Kamps MP
Mol Cell Biol; 1994 Jun; 14(6):3938-48. PubMed ID: 7910944
[TBL] [Abstract][Full Text] [Related]
4. An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1.
Calvo KR; Knoepfler P; McGrath S; Kamps MP
Oncogene; 1999 Dec; 18(56):8033-43. PubMed ID: 10637514
[TBL] [Abstract][Full Text] [Related]
5. DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation.
Kamps MP; Wright DD; Lu Q
Oncogene; 1996 Jan; 12(1):19-30. PubMed ID: 8552391
[TBL] [Abstract][Full Text] [Related]
6. E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts.
Fu X; Kamps MP
Mol Cell Biol; 1997 Mar; 17(3):1503-12. PubMed ID: 9032278
[TBL] [Abstract][Full Text] [Related]
7. The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements.
Knoepfler PS; Kamps MP
Oncogene; 1997 May; 14(21):2521-31. PubMed ID: 9191052
[TBL] [Abstract][Full Text] [Related]
8. Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias.
LeBrun DP; Cleary ML
Oncogene; 1994 Jun; 9(6):1641-7. PubMed ID: 8183558
[TBL] [Abstract][Full Text] [Related]
9. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
Lu Q; Knoepfler PS; Scheele J; Wright DD; Kamps MP
Mol Cell Biol; 1995 Jul; 15(7):3786-95. PubMed ID: 7791786
[TBL] [Abstract][Full Text] [Related]
10. [Identification of proteins associated with transcription factors HOXA9 and E2A-PBX1 by tandem affinity purification].
Shestakova EA; Boutin M; Bourassa S; Bonneil E; Bijl JJ
Mol Biol (Mosk); 2017; 51(3):490-501. PubMed ID: 28707666
[TBL] [Abstract][Full Text] [Related]
11. Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1.
Knoepfler PS; Calvo KR; Chen H; Antonarakis SE; Kamps MP
Proc Natl Acad Sci U S A; 1997 Dec; 94(26):14553-8. PubMed ID: 9405651
[TBL] [Abstract][Full Text] [Related]
12. Selective repression of transcriptional activators by Pbx1 does not require the homeodomain.
Lu Q; Kamps MP
Proc Natl Acad Sci U S A; 1996 Jan; 93(1):470-4. PubMed ID: 8552663
[TBL] [Abstract][Full Text] [Related]
13. E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia.
Pi WC; Wang J; Shimada M; Lin JW; Geng H; Lee YL; Lu R; Li D; Wang GG; Roeder RG; Chen WY
Blood; 2020 Jul; 136(1):11-23. PubMed ID: 32276273
[TBL] [Abstract][Full Text] [Related]
14. Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.
Smith KS; Jacobs Y; Chang CP; Cleary ML
Oncogene; 1997 Jun; 14(24):2917-26. PubMed ID: 9205098
[TBL] [Abstract][Full Text] [Related]
15. Critical role for a single leucine residue in leukemia induction by E2A-PBX1.
Bayly R; Murase T; Hyndman BD; Savage R; Nurmohamed S; Munro K; Casselman R; Smith SP; LeBrun DP
Mol Cell Biol; 2006 Sep; 26(17):6442-52. PubMed ID: 16914730
[TBL] [Abstract][Full Text] [Related]
16. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.
Kamps MP; Look AT; Baltimore D
Genes Dev; 1991 Mar; 5(3):358-68. PubMed ID: 1672117
[TBL] [Abstract][Full Text] [Related]
17. Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins.
Chang CP; Jacobs Y; Nakamura T; Jenkins NA; Copeland NG; Cleary ML
Mol Cell Biol; 1997 Oct; 17(10):5679-87. PubMed ID: 9315626
[TBL] [Abstract][Full Text] [Related]
18. Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia.
McWhirter JR; Neuteboom ST; Wancewicz EV; Monia BP; Downing JR; Murre C
Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11464-9. PubMed ID: 10500199
[TBL] [Abstract][Full Text] [Related]
19. E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells.
Bayly R; Chuen L; Currie RA; Hyndman BD; Casselman R; Blobel GA; LeBrun DP
J Biol Chem; 2004 Dec; 279(53):55362-71. PubMed ID: 15507449
[TBL] [Abstract][Full Text] [Related]
20. Oncoprotein E2A-Pbx1 immortalizes a myeloid progenitor in primary marrow cultures without abrogating its factor-dependence.
Kamps MP; Wright DD
Oncogene; 1994 Nov; 9(11):3159-66. PubMed ID: 7936638
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]