BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 7970720)

  • 1. Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2.
    Janes PW; Daly RJ; deFazio A; Sutherland RL
    Oncogene; 1994 Dec; 9(12):3601-8. PubMed ID: 7970720
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of the Grb2 gene in human breast cancer cell lines.
    Daly RJ; Binder MD; Sutherland RL
    Oncogene; 1994 Sep; 9(9):2723-7. PubMed ID: 8058337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells.
    Tari AM; Hung MC; Li K; Lopez-Berestein G
    Oncogene; 1999 Feb; 18(6):1325-32. PubMed ID: 10022814
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Significance of the Grb2 and son of sevenless (Sos) proteins in human bladder cancer cell lines.
    Watanabe T; Shinohara N; Moriya K; Sazawa A; Kobayashi Y; Ogiso Y; Takiguchi M; Yasuda J; Koyanagi T; Kuzumaki N; Hashimoto A
    IUBMB Life; 2000 Apr; 49(4):317-20. PubMed ID: 10995035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p21Ras activation by the guanine nucleotide exchange factor Sos, requires the Sos/Grb2 interaction and a second ligand-dependent signal involving the Sos N-terminus.
    Byrne JL; Paterson HF; Marshall CJ
    Oncogene; 1996 Nov; 13(10):2055-65. PubMed ID: 8950972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Association of Grb2 with Sos and Ras with Raf-1 upon gamma irradiation of breast cancer cells.
    Suy S; Anderson WB; Dent P; Chang E; Kasid U
    Oncogene; 1997 Jul; 15(1):53-61. PubMed ID: 9233777
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos.
    Buday L; Warne PH; Downward J
    Oncogene; 1995 Oct; 11(7):1327-31. PubMed ID: 7478553
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.
    Gale NW; Kaplan S; Lowenstein EJ; Schlessinger J; Bar-Sagi D
    Nature; 1993 May; 363(6424):88-92. PubMed ID: 8386805
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
    Li N; Batzer A; Daly R; Yajnik V; Skolnik E; Chardin P; Bar-Sagi D; Margolis B; Schlessinger J
    Nature; 1993 May; 363(6424):85-8. PubMed ID: 8479541
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.
    Zhang T; Ma J; Cao X
    Biochem J; 2003 Dec; 376(Pt 2):457-64. PubMed ID: 14498832
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
    Egan SE; Giddings BW; Brooks MW; Buday L; Sizeland AM; Weinberg RA
    Nature; 1993 May; 363(6424):45-51. PubMed ID: 8479536
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new function for phospholipase C-gamma1: coupling to the adaptor protein GRB2.
    Pei Z; Maloney JA; Yang L; Williamson JR
    Arch Biochem Biophys; 1997 Sep; 345(1):103-10. PubMed ID: 9281317
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc.
    Kranenburg O; Verlaan I; Hordijk PL; Moolenaar WH
    EMBO J; 1997 Jun; 16(11):3097-105. PubMed ID: 9214627
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
    Hu Y; Bowtell DD
    Oncogene; 1996 May; 12(9):1865-72. PubMed ID: 8649846
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insulin-induced dissociation of Sos from Grb2 does not contribute to the down regulation of Ras activation.
    Corbalan-Garcia S; Degenhardt KR; Bar-Sagi D
    Oncogene; 1996 Mar; 12(5):1063-8. PubMed ID: 8649797
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor.
    Basu T; Warne PH; Downward J
    Oncogene; 1994 Dec; 9(12):3483-91. PubMed ID: 7970708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2.
    Xu XX; Yi T; Tang B; Lambeth JD
    Oncogene; 1998 Mar; 16(12):1561-9. PubMed ID: 9569023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Grb2-associated docking protein in EGF- and insulin-receptor signalling.
    Holgado-Madruga M; Emlet DR; Moscatello DK; Godwin AK; Wong AJ
    Nature; 1996 Feb; 379(6565):560-4. PubMed ID: 8596638
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.
    Rozakis-Adcock M; McGlade J; Mbamalu G; Pelicci G; Daly R; Li W; Batzer A; Thomas S; Brugge J; Pelicci PG; Schlessinger J; Pawson T
    Nature; 1992 Dec; 360(6405):689-92. PubMed ID: 1465135
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Grb2 downregulation leads to Akt inactivation in heregulin-stimulated and ErbB2-overexpressing breast cancer cells.
    Lim SJ; Lopez-Berestein G; Hung MC; Lupu R; Tari AM
    Oncogene; 2000 Dec; 19(54):6271-6. PubMed ID: 11175341
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.