These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 7973659)

  • 1. Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits.
    Miyazaki T; Kawahara A; Fujii H; Nakagawa Y; Minami Y; Liu ZJ; Oishi I; Silvennoinen O; Witthuhn BA; Ihle JN
    Science; 1994 Nov; 266(5187):1045-7. PubMed ID: 7973659
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.
    Kirken RA; Rui H; Malabarba MG; Howard OM; Kawamura M; O'Shea JJ; Farrar WL
    Cytokine; 1995 Oct; 7(7):689-700. PubMed ID: 8580378
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID.
    Russell SM; Johnston JA; Noguchi M; Kawamura M; Bacon CM; Friedmann M; Berg M; McVicar DW; Witthuhn BA; Silvennoinen O
    Science; 1994 Nov; 266(5187):1042-5. PubMed ID: 7973658
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction.
    Kawahara A; Minami Y; Miyazaki T; Ihle JN; Taniguchi T
    Proc Natl Acad Sci U S A; 1995 Sep; 92(19):8724-8. PubMed ID: 7568005
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation.
    Liu KD; Gaffen SL; Goldsmith MA; Greene WC
    Curr Biol; 1997 Nov; 7(11):817-26. PubMed ID: 9382798
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation.
    Nelson BH; McIntosh BC; Rosencrans LL; Greenberg PD
    Proc Natl Acad Sci U S A; 1997 Mar; 94(5):1878-83. PubMed ID: 9050873
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.
    Fujii H; Nakagawa Y; Schindler U; Kawahara A; Mori H; Gouilleux F; Groner B; Ihle JN; Minami Y; Miyazaki T
    Proc Natl Acad Sci U S A; 1995 Jun; 92(12):5482-6. PubMed ID: 7777534
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.
    Zhu MH; Berry JA; Russell SM; Leonard WJ
    J Biol Chem; 1998 Apr; 273(17):10719-25. PubMed ID: 9553136
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.
    Nelson BH; Lord JD; Greenberg PD
    Mol Cell Biol; 1996 Jan; 16(1):309-17. PubMed ID: 8524310
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins).
    Nielsen M; Svejgaard A; Röpke C; Nordahl M; Odum N
    Proc Natl Acad Sci U S A; 1995 Nov; 92(24):10995-9. PubMed ID: 7479924
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line.
    Higuchi M; Asao H; Tanaka N; Oda K; Takeshita T; Nakamura M; Van Snick J; Sugamura K
    Eur J Immunol; 1996 Jun; 26(6):1322-7. PubMed ID: 8647212
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of IL-2 signaling.
    Higuchi M; Asao H; Tanaka N; Oda K; Takeshita T; Sugamura K
    Leukemia; 1997 Apr; 11 Suppl 3():416-7. PubMed ID: 9209410
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IL-2 signaling involves recruitment and activation of multiple protein tyrosine kinases by the IL-2 receptor.
    Taniguchi T; Miyazaki T; Minami Y; Kawahara A; Fujii H; Nakagawa Y; Hatakeyama M; Liu ZJ
    Ann N Y Acad Sci; 1995 Sep; 766():235-44. PubMed ID: 7486666
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor gammac chain in the Jak3-independent signal transduction.
    Tsujino S; Miyazaki T; Kawahara A; Maeda M; Taniguchi T; Fujii H
    Genes Cells; 1999 Jun; 4(6):363-73. PubMed ID: 10421845
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential substrate recognition capabilities of Janus family protein tyrosine kinases within the interleukin 2 receptor (IL2R) system: Jak3 as a potential molecular target for treatment of leukemias with a hyperactive Jak-Stat signaling machinery.
    Witthuhn BA; Williams MD; Kerawalla H; Uckun FM
    Leuk Lymphoma; 1999 Jan; 32(3-4):289-97. PubMed ID: 10037026
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Convergence of signaling transduced by prolactin (PRL)/cytokine chimeric receptors on PRL-responsive gene transcription.
    Ferrag F; Chiarenza A; Goffin V; Kelly PA
    Mol Endocrinol; 1996 Apr; 10(4):451-60. PubMed ID: 8721989
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interleukin-2 (IL-2) upregulates BAG-1 gene expression through serine-rich region within IL-2 receptor beta c chain.
    Adachi M; Sekiya M; Torigoe T; Takayama S; Reed JC; Miyazaki T; Minami Y; Taniguchi T; Imai K
    Blood; 1996 Dec; 88(11):4118-23. PubMed ID: 8943845
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.
    Tanaka N; Asao H; Ohbo K; Ishii N; Takeshita T; Nakamura M; Sasaki H; Sugamura K
    Proc Natl Acad Sci U S A; 1994 Jul; 91(15):7271-5. PubMed ID: 8041779
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the interleukin 2 receptor: a possible role for tyrosine phosphatases.
    Ellery JM; Kempshall SJ; Nicholls PJ
    Cell Signal; 2000 Jun; 12(6):367-73. PubMed ID: 10889465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Possible mechanism for the alpha subunit of the interleukin-2 receptor (CD25) to influence interleukin-2 receptor signal transduction.
    Ellery JM; Nicholls PJ
    Immunol Cell Biol; 2002 Aug; 80(4):351-7. PubMed ID: 12121224
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.